Dr Marta Milo
Lecturer in Computational Biology
Department of Biomedical Science
The University of Sheffield
Sheffield S10 2TN
Room: Alfred Denny C224a
Telephone: +44 (0) 114 222 4673
email : email@example.com
- 2012-present: Lecturer in Computational Biology
- 2008-2012: Bioinformatics Research Fellow, NIHR Cardiovascular Biomedical Research Unit, Sheffield Teaching Hospitals NHS Trust.
- 2004-2008: Wellcome Trust Research Fellow, University of Sheffield, UK.
- 2003-2004: Postdoctoral Researcher at the Department of Biomedical Science, University of Sheffield, UK.
- 2001-2003: Postdoctoral Fellow at the Dept of Computer Science, University of Sheffield, UK.
- 1996-2000: PhD in Applied Mathematics and Computer Science at the University of Naples 'Federico II'.
- 1995-1996: Computer Science and Statistics Consulting at FORMEZ c/o OLIVETTI Research Centre, Arco Felice, Italy.
- 1994-1995: Qualification in Computer Science and Statistics applied to Public Administrative systems, at FORMEZ c/o OLIVETTI Research Centre, Arco Felice, Italy..
- 1989-1994: Degree in Mathematics, University of Naples "Federico II'', Italy.
- 2000: PhD in Applied Mathematics and Computer Science, The University of Naples, "Federico II"
- 1994: "Laurea" in Mathematics, The University of Naples "Federico II"
To understand and define the source of uncertainty in quantitative biology it is a key aspect for improving sensitivity and accuracy in the analysis of high throughput genomic data. My research interests focus on developing computational tools, pipelines, appropriate experimental designs and protocols to assist in improving accuracy and sensitivity in the analysis of biological data. Major research activities are:
- propagation of uncertainty, associated to low-level data, in downstream analysis of microarray data;
- quantification and inference of gene expression levels using probabilistic models;
- inference of gene networks using regulatory data and gene expression data;
- Integrated approaches for the analysis of Next Generation Sequencing data.
Activities and distinctions
- Member of PUMA project (Propagating Uncertainty in Microarray Analysis)
- Reviewer for leading scientific journals
- Member of Quantitave Biology Group
- Flinn LJ, Keatinge M, Bretaud S, Mortiboys H, Matsui H, De Felice E, Woodroof HI, Brown L, McTighe A, Soellner R, Allen CE, Heath PR, Milo M, Muqit MM, Reichert AS, Köster RW, Ingham PW & Bandmann O (2013) TigarB causes mitochondrial dysfunction and neuronal loss in PINK1 deficiency.. Ann Neurol.
- Knuckles P, Vogt MA, Lugert S, Milo M, Chong MM, Hautbergue GM, Wilson SA, Littman DR & Taylor V (2012) Drosha regulates neurogenesis by controlling neurogenin 2 expression independent of microRNAs.. Nat Neurosci, 15(7), 962-969.
- Knuckles P, Vogt MA, Lugert S, Taylor V, Milo M, Chong MMW, Littman DR, Hautbergue GM & Wilson SA (2012) Drosha regulates neurogenesis by controlling Neurogenin 2 expression independent of microRNAs. Nature Neuroscience, 15(7), 962-969.
- Chen W, Jongkamonwiwat N, Abbas L, Eshtan SJ, Johnson SL, Kuhn S, Milo M, Thurlow JK, Andrews PW, Marcotti W, Moore HD & Rivolta MN (2012) Restoration of auditory evoked responses by human ES-cell-derived otic progenitors.. Nature, 490(7419), 278-282.
- Chen W, Jongkamonwiwat N, Abbas L, Eshtan SJ, Thurlow JK, Andrews PW, Moore HD, Rivolta MN, Johnson SL, Kuhn S, Milo M & Marcotti W (2012) Restoration of auditory evoked responses by human ES-cell-derived otic progenitors. Nature, 490(7419), 278-282.