Recent Publications
Andrews PW | Battaglia G | Borycki AG | Chico TJ | Cooper GJ | Cunliffe VT | Davletov B | Furley AJ | Grundy D | Holley MC | Juusola M | Marcotti W | Miller G | Milo M | Moore H | Nassar MA | Placzek M | Rashbass P | Renshaw SA | Rivolta M | Robson L | Roehl HH | Seward E | Smythe C | Smythe E | Strutt D | van Eeden FJ| Whitfield TT | Whitworth AJ | Winder SJ | Zeidler MP
Andrews PW
The International Stem Cell Initiative, Amps K, Andrews PW, et al.
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage.
Nat Biotechnol. 2011 29:1132-1144.
Sood A, Salih S, Roh D, Lacharme-Lora L, Parry M, Hardiman B, Keehan R, Grummer R, Winterhager E, Gokhale PJ, Andrews PW, Abbott C, Forbes K, Westwood M, Aplin JD, Ingham E, Papageorgiou I, Berry M, Liu J, Dick AD, Garland RJ, Williams N, Singh R, Simon AK, Lewis M, Ham J, Roger L, Baird DM, Crompton LA, Caldwell MA, Swalwell H, Birch-Machin M, Lopez-Castejon G, Randall A, Lin H, Suleiman MS, Evans WH, Newson R, Case CP.
Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness.
Nat Nanotechnol. 2011 6:824-33.
Barbaric I, Jones M, Buchner K, Baker D, Andrews PW, Moore HD.
Pinacidil enhances survival of cryopreserved human embryonic stem cells.
Cryobiology. 2011 63:298-305.
Andrews PW.
Toward safer regenerative medicine.
Nat Biotechnol. 2011 29:803-5. No abstract available.
Tonge PD, Shigeta M, Schroeder T, Andrews PW.
Functionally defined substates within the human embryonic stem cell compartment.
Stem Cell Res. 2011 7:145-53.
Fazeli A, Liew CG, Matin MM, Elliott S, Jeanmeure LF, Wright PC, Moore H, Andrews PW.
Altered patterns of differentiation in karyotypically abnormal human embryonic stem cells.
Int J Dev Biol. 2011 55:175-80.
Wright A, Andrews N, Bardsley K, Nielsen JE, Avery K, Pewsey E, Jones M, Harley D, Nielsen AR, Moore H, Gokhale P, Rajpert-De Meyts E, Andrews PW, Walsh J, Harrison NJ.
Mapping the stem cell state: eight novel human embryonic stem and embryonal carcinoma cell antibodies.
Int J Androl. 2011 34: e175-87;
Goldring CE, Duffy PA, Benvenisty N, Andrews PW, Ben-David U, Eakins R, French N, Hanley NA, Kelly L, Kitteringham NR, Kurth J, Ladenheim D, Laverty H, McBlane J, Narayanan G, Patel S, Reinhardt J, Rossi A, Sharpe M, Park BK.
Assessing the safety of stem cell therapeutics.
Cell Stem Cell. 2011 8:618-28. Review.
Barbaric I, Jones M, Harley DJ, Gokhale PJ, Andrews PW.
High-content screening for chemical modulators of embryonal carcinoma cell differentiation and survival.
J Biomol Screen. 2011 16:603-17.
Battaglia G
Hearnden V, MacNeil S, Battaglia G.
Tracking nanoparticles in three-dimensional tissue-engineered models using confocal laser scanning microscopy.
Methods Mol Biol. 2011;695:41-51.
Flores-Merino MV, Chirasatitsin S, Lopresti C, Reilly GC, Battaglia G, Engler AJ.
Nanoscopic mechanical anisotropy in hydrogel surfaces.
Soft Matter. 2010 6:4466-4470.
Murdoch C, Reeves KJ, Hearnden V, Colley H, Massignani M, Canton I, Madsen J, Blanazs A, Armes SP, Lewis AL, Macneil S, Brown NJ, Thornhill MH, Battaglia G.
Internalization and biodistribution of polymersomes into oral squamous cell carcinoma cells in vitro and in vivo.
Nanomedicine (Lond). 2010 5:1025-36.
Lomas H, Du J, Canton I, Madsen J, Warren N, Armes SP, Lewis AL, Battaglia G.
Efficient encapsulation of plasmid DNA in pH-sensitive PMPC-PDPA polymersomes: study of the effect of PDPA block length on copolymer-DNA binding affinity.
Macromol Biosci. 2010 May 14;10(5):513-30.
Brown L, McArthur SL, Wright PC, Lewis A, Battaglia G.
Polymersome production on a microfluidic platform using pH sensitive block copolymers.
Lab Chip. 2010 May 17. [Epub ahead of print]
Massignani M, Canton I, Sun T, Hearnden V, Macneil S, Blanazs A, Armes SP, Lewis A, Battaglia G.
Enhanced fluorescence imaging of live cells by effective cytosolic delivery of probes.
PLoS One. 2010 May 3;5(5):e10459.
Picard C, Hearnden V, Massignani M, Achouri S, Battaglia G, MacNeil S, Donald A.
A micro-incubator for cell and tissue imaging.
Biotechniques. 2010 Feb;48(2):135-8.
Borycki AG
Borycki AG.
The myotomal basement membrane: Insight into laminin-111 function and its control by Sonic hedgehog signaling.
Cell Adh Migr. 2013 Jan 1;7: 72-81
Balczerski B, Zakaria S, Tucker AS, Borycki AG, Koyama E, Pacifici M, Francis-West P.
Distinct spatiotemporal roles of hedgehog signalling during chick and mouse cranial base and axial skeleton development.
Dev Biol. 2012 Nov 15;371(2):203-14.
Anderson C, Williams VC, Moyon B, Daubas P, Tajbakhsh S, Buckingham ME, Shiroishi T, Hughes SM, Borycki AG.
Sonic hedgehog acts cell-autonomously on muscle precursor cells to generate limb muscle diversity.
Genes Dev. 2012 Sep 15;26(18):2103-17.
Van Hateren NJ, Das RM, Hautbergue GM, Borycki AG, Placzek M, Wilson SA.
FatJ acts via the Hippo mediator Yap1 to restrict the size of neural progenitor cell pools.
Development. 2011 May;138(10):1893-1902.
Coy S, Caamaño JH, Carvajal J, Cleary ML, Borycki AG.
A Novel Gli3 Enhancer Controls the Gli3 Spatiotemporal Expression Pattern through a TALE Homeodomain Protein Binding Site.
Mol Cell Biol. 2011 Apr;31(7):1432-43
Coy SE, Borycki AG.
Expression analysis of TALE family transcription factors during avian development.
Dev Dyn. 2010 Apr;239(4):1234-45.
Anderson C, Thorsteinsdóttir S, Borycki AG.
Sonic hedgehog-dependent synthesis of laminin alpha1 controls basement membrane assembly in the myotome.
Development. 2009 Oct;136(20):3495-504.
Chico TJ
Holden BJ, Bratt DG, Chico TJ.
Molecular control of vascular development in the zebrafish.
Birth Defects Res C Embryo Today. 2011 Jun;93(2):134-40.
Ellam T, Wilkie M, Chamberlain J, Crossman D, Eastell R, Francis S, Chico TJ.
Dietary Phosphate Modulates Atherogenesis and Insulin Resistance in Apolipoprotein E Knockout Mice.
Arterioscler Thromb Vasc Biol. 2011 Jun 2. [Epub ahead of print]
Gray C, Loynes CA, Whyte MK, Crossman DC, Renshaw SA, Chico TJ.
Simultaneous intravital imaging of macrophage and neutrophil behaviour during inflammation using a novel transgenic zebrafish.
Thromb Haemost. 2011 May;105(5):811-9.
Bourke L, Tew GA, Milo M, Crossman DC, Saxton JM, Chico TJ.
Study protocol: a randomised controlled trial investigating the effect of exercise training on peripheral blood gene expression in patients with stable angina.
BMC Public Health. 2010 10:620.
McLeish JA, Chico TJ, Taylor HB, Tucker C, Donaldson K, Brown SB.
Skin exposure to micro- and nano-particles can cause haemostasis in zebrafish larvae.
Thromb Haemost. 2010 Mar 31;103(4):797-807
Chico TJ, Milo M, Crossman DC.
The genetics of cardiovascular disease: new insights from emerging approaches.
J Pathol. 2010 Jan;220(2):186-97. Review.
Cooper GJ
Abbas L, Hajihashemi S, Stead LF, Cooper GJ, Ware TL, Munsey TS, Whitfield TT, White SJ.
Functional and developmental expression of a zebrafish Kir1.1 (ROMK) potassium channel homologue Kcnj1.
J Physiol. 2011 Mar 15;589(Pt 6):1489-503.
Laycock Cooper GJ, Ong AC, Robson L.
A novel dephosphorylation-activated conductance in a mouse renal collecting duct cell line.
Exp Physiol. 2009 Aug;94(8):914-27.
Stewart GS, Thistlethwaite A, Lees H, Cooper GJ, Smith CP.
Vasopressin regulation of the renal UT-A3 urea transporter.
Am J Physiol Renal Physiol. 2009 Mar;296(3):F642-8.
Cunliffe VT
Baxendale S, Holdsworth CJ, Meza Santoscoy PL, Harrison MR, Fox J, Parkin CA, Ingham PW, Cunliffe VT.
Identification of compounds with anti-convulsant properties in a zebrafish model of epileptic seizures.
Dis Model Mech. 2012 Nov;5(6):773-84. doi: 10.1242/dmm.010090. Epub 2012 Jun 21.
Lightman EG, Harrison MR, Cunliffe VT.
Opposing actions of histone deacetylase 1 and Notch signalling restrict expression of erm and fgf20a to hindbrain rhombomere centres during zebrafish neurogenesis.
Int J Dev Biol. 2011;55(6):597-602.
Harrison MR, Georgiou AS, Spaink HP, Cunliffe VT.
The epigenetic regulator Histone Deacetylase 1 promotes transcription of a core neurogenic programme in zebrafish embryos.
BMC Genomics. 2011 Jan 12;12:24.
Butler R, Wood JD, Landers JA, Cunliffe VT.
Genetic and chemical modulation of spastin-dependent axon outgrowth in zebrafish embryos indicates a role for impaired microtubule dynamics in hereditary spastic paraplegia.
Dis Model Mech. 2010 Nov-Dec;3(11-12):743-51. Epub 2010 Sep 9
Walker RA, Cunliffe VT, Whittle JD, Steele DA, Short RD.
Submillimeter-scale surface gradients of immobilized protein ligands.
Langmuir. 2009 Apr 21;25(8):4243-6.
Wood JD, Bonath F, Kumar S, Ross CA, Cunliffe VT.
Disrupted-in-schizophrenia 1 and neuregulin 1 are required for the specification of oligodendrocytes and neurones in the zebrafish brain.
Hum Mol Genet. 2009 Feb 1;18(3):391-404.
Davletov B
Ferrari E, Soloviev M, Niranjan D, Arsenault J, Gu C, Vallis Y, O'Brien J, Davletov B. (2012)
Assembly of protein building blocks using a short synthetic peptide
Bioconjug Chem. 23:479-84
Raingo J, Khvotchev M, Liu P, Darios F, Li YC, Ramirez DM, Adachi M, Lemieux P, Toth K, Davletov B, Kavalali ET. (2012)
VAMP4 directs synaptic vesicles to a pool that selectively maintains asynchronous neurotransmission
Nat Neurosci. 15:738-45
Ferrari E, Maywood E, Restani L, Caleo M, Pirazzini M, Rossetto O, Hastings M, Niranjan D, Schiavo G, Davletov B. (2011)
Re-assembled botulinum neurotoxin inhibits CNS functions without systemic toxicity
Toxins 3, 345-55
Darios F, Niranjan D, Ferrari E, Zhang F, Soloviev M, Rummel A, Bigalke H, Suckling J, Ushkaryov Y, Naumenko N, Shakirzyanova A, Giniatullin R, Maywood E, Hastings M, Binz T, Davletov B. (2010)
SNARE tagging allows step-wise assembly of a multimodular medicinal toxin
Proc Nat Acad Sci USA 107, 18197-201
Darios F, Ruipérez V, López I, Villanueva J, Gutierrez LM, Davletov B. (2010)
Alpha-synuclein sequesters arachidonic acid to modulate SNARE-mediated exocytosis.
EMBO Rep 11, 528-33
Davletov B, Montecucco C. (2010)
Lipid function at synapses.
Curr Opin Neurobiol 20, 543-9 Review
Darios, F., Wasser, C., Shakirzyanova, A., Giniatullin, A., Goodman, K., Munoz-Bravo, J. L., Raingo, J., Jorgacevski, J., Kreft, M., Zorec, R., Rosa, J. M., Gandia, L., Gutierrez, L. M., Binz, T., Giniatullin, R., Kavalali, E. T. and Davletov, B. (2009)
Sphingosine facilitates SNARE complex assembly and activates synaptic vesicle exocytosis.
Neuron 62, 683-94 (featured in the same issue of Neuron and in Frontiers in Neuroscience 2010)
Furley AJ
Bizzoca, A., Corsi, P., Polizzi, A., Pinto, M. F., Xenaki, D., Furley, A. J., and Gennarini, G. (2012).
F3/Contactin acts as a modulator of neurogenesis during cerebral cortex development.
Developmental Biology 365, 133-151.
Dang, P., Smythe, E., and Furley, A. J. (2012).
TAG1 Regulates the Endocytic Trafficking and Signaling of the Semaphorin3A Receptor Complex.
Journal of Neuroscience 32, 10370-10382.
Buchner, D. A., Geisinger, J. M., Glazebrook, P. A., Morgan, M. G., Spiezio, S. H., Kaiyala, K. J., Schwartz, M. W., Sakurai, T., Furley, A. J., Kunze, D. L., Croniger, C. M., and Nadeau, J. H. (2012).
The juxtaparanodal proteins CNTNAP2 and TAG1 regulate diet-induced obesity.
Mammalian Genome 23, 431-442.
Xenaki D, Martin IB, Yoshida L, Ohyama K, Gennarini G, Grumet M, Sakurai T, Furley AJ.
F3/contactin and TAG1 play antagonistic roles in the regulation of sonic hedgehog-induced cerebellar granule neuron progenitor proliferation.
Development. 2011 138:519-29.
Grundy D
Jiang W, Adam IJ, Kitsanta P, Tiernan J, Hill C, Shorthouse A, Grundy D.
'First-in-man': characterising the mechanosensitivity of human colonic afferents.
Gut. 2011 60:281-2. Epub 2010 Nov 23.
Krueger D, Foerster M, Mueller K, Zeller F, Slotta-Huspenina J, Donovan J, Grundy D, Schemann M.
Signaling mechanisms involved in the intestinal pro-secretory actions of hydrogen sulfide.
Neurogastroenterol Motil. 2010 22:1224-31, e319-20.
Lubbers T, De Haan JJ, Hadfoune M, Zhang Y, Luyer MD, Grundy D, Buurman WA, Greve JW.
Lipid-enriched enteral nutrition controls the inflammatory response in murine Gram-negative sepsis.
Crit Care Med. 2010 38:1996-2002.
Keating C, Martinez V, Ewart L, Gibbons S, Grundy L, Valentin JP, Grundy D.
The validation of an in vitro colonic motility assay as a biomarker for gastrointestinal adverse drug reactions.
Toxicol Appl Pharmacol. 2010 Jun 15;245(3):299-309.
Daly DM, Chess-Williams R, Chapple C, Grundy D.
Reply from Authors re: Delphine Behr-Roussel, Francois A. Giuliano. Sensory Effects of Antimuscarinics: Still a Matter of Debate. Eur Urol. In press. doi:10.1016/j.eururo.2010.01.010.
Eur Urol. 2010 Feb 4. [Epub ahead of print]
Daly DM, Chess-Williams R, Chapple C, Grundy D.
The Inhibitory Role of Acetylcholine and Muscarinic Receptors in Bladder Afferent Activity.
Eur Urol. 2010 Jan 4. [Epub ahead of print]
Holley MC
Lin Z, Perez P, Sun Z, Liu JJ, Shin JH, Hyrc KL, Samways D, Egan T, Holley MC, Bao J. (2012)
Reprogramming of single-cell-derived mesenchymal stem cells into hair cell-like cells.
Otol Neurotol. [Epub ahead of print]
Zetes D, Tolomeo J & Holley MC (2012)
Structure and mechanics of supporting cells in the guinea pig organ of Corti.
PLoS ONE 7(11): e49338. doi:10.1371/journal.pone.0049338
Eckrich T, Varakina K, Johnson S, Franz C, Singer W, Kuhn S, Knipper M, Holley M, Marcotti W (2012)
Development and Function of the Voltage-Gated Sodium Current in Immature Mammalian Cochlear Inner Hair Cells.
PLoS ONE 7(9): e45732. doi:10.1371/journal.pone.0045732
Zampini V, Rüttiger L, Johnson S, Franz C, Furness DN, Waldhaus J, Xiong H, Hackney CM, Holley MC, Offenhauser N, Di Fiore PP, Knipper M, Masetto S & Marcotti W.
Eps8 Regulates Hair Bundle Length and Functional Maturation of Mammalian Auditory Hair Cells.
PloS Biology 2011 Apr;9(4):e1001048.
Kuhn S, Johnson SL, Furness DN, Chen J, Ingham N, Hilton JM, Steffes G, Lewis MA, Zampini V, Hackney CM, Masetto S, Holley MC, Steel KP & Marcotti W.
miR-96 regulates the progression of differentiation in mammalian cochlear inner and outer hair cells.
Proc Natl Acad Sci USA 108:2355-60.
Dong Y, Sui L, Yamaguchi F, Kamitori K, Hirata Y, Hossain MA, Suzuki A, Holley MC, Tokuda M.
Phosphatase and tensin homolog deleted on chromosome 10 regulates sensory cell proliferation and differentiation of hair bundles in the mammalian cochlea.
Neuroscience. 2010. 170:1304-13.
Dong Y, Sui L, Yamaguchi F, Kamitori K, Hirata Y, Suzuki A, Holley M, Tokuda M.
Role of phosphatase and tensin homolog in the development of the mammalian auditory system.
Neuroreport. 2010 Jul 14;21(10):731-5.
Honkela A, Milo M, Holley M, Rattray M, Lawrence ND
Ranking of gene regulators through differential equations and Gaussian processes.
Proceedings of 2010 IEEE International Workshop on Machine Learning for Signal Processing.
Sekiya T, Matsumoto M, Kojima K, Ono K, Kikkawa Y, Kada S, Ogita H, Horie R, Viola A, Holley M, Ito J
Mechanical stress-induced reactive gliosis in the auditory nerve and cochlear nucleus;
J Neurosurg. 2010 Apr 2. [Epub ahead of print]
Holley M, Rhodes C, Kneebone A, Herde MK, Fleming M, Steel KP
Emx2 and early hair cell development in the mouse inner ear.
Dev Biol. Feb 9. 2010 [Epub ahead of print]
Sanchez-Calderon H, Rodriguez-de la Rosa L, Milo M, Pichel JG, Holley M, Varela-Nieto I
RNA microarray analysis in prenatal mouse cochlea reveals novel IGF-I target genes: implication of MEF2 and FOXM1 transcription factors.
PLoS One, 2010 5:e8699.
Juusola M
Heimonen, K., Immonen, E.-V., Frolov, R., Salmela, I., Juusola, M., Vähäsöyrinki, M., and Weckström, M.* (2012).
Signal coding in cockroach photoreceptors is tuned to dim environments.
J. Neurophysiol. 108:2641-2652.
Song, Z., Postma, M., Billings, S.A., Coca, D*, Hardie, R.C* & Juusola, M* (2012).
Stochastic, Adaptive Sampling of Information by Microvilli in Fly Photoreceptors.
Current Biology 22: 1371-1380.
Wardill, T.J., List, O., Li, X., Dongre, S., McCulloch, M., Ting, C.Y., O'Kane, C.J., Tang, S., Lee, C.H., Hardie, R.C. & Juusola, M.* (2012).
Multiple Spectral Inputs Improve Motion Discrimination in the Drosophila Visual System.
Science 336: 925-931.
Friederich, U., Billings, S.A., Juusola, M.* & Coca, D.* (2012).
Reverse Engineering Gain Adaptation in Sensory Systems.
Acta Press, Proceedings of the 9th IASTED International Conference on Biomedical Engineering, doi:10.2316/P.2012.764-125.
Winder, S.J.*, Lipscomb, L., Parkin, C.A. & Juusola, M. (2011).
The proteasomal inhibitor MG132 prevents muscular dystrophy in zebrafish.
PLoS Curr. 2011 Nov 17;3
Abou Tayoun, A.N., Li, X., Chu, B., Hardie, R.C., Juusola, M.* & Dolph, P.J.* (2011).
The Drosophila SK channel (dSK) contributes to photoreceptor performance by mediating sensitivity control at the first visual network.
J. Neurosci. 31: 13897-13910.
Gonzalez-Bellido, P.T., Wardill, T.J. & Juusola, M.* (2011)
Compound eyes and retinal information processing in miniature dipteran species match their specific ecological demands.
Proc Natl Acad Sci USA 108: 4224-4229.
Marcotti W
Marcotti W.
Sharpey-Schafer Lecture: Functional assembly of mammalian cochlear hair cells.
Exp Physiol. 2011 Dec 16. [Epub ahead of print]
Johnson SL, Beurg M, Marcotti W & Fettipplace R
Prestin-driven cochlear amplification is not limited by the outer hair cell membrane time constant.
Neuron. 2011 70:1143-54
Alagramam KN, Goodyear RJ, Geng R, Furness DN, van Aken A, Marcotti W, Kros CJ & Richardson GP
Mice with mutations in protocadherin 15 and cadherin 23 lack tip links and have defects in mechanotransduction.
PloS One 6: 2011. e19183.
Johnson SL, Eckrich T, Kuhn S, Zampini V, Franz C, Ranatunga KM, Roberts TP, Masetto S, Knipper M, Kros CJ & Marcotti W
Position-dependent patterning of spontaneous action potentials in immature cochlear inner hair cells.
Nature Neurosci Published online: 15 May 2011 | doi:10.1038/nn.2803.
Zampini V, Rüttiger L, Johnson S, Franz C, Furness DN, Waldhaus J, Xiong H, Hackney CM, Holley MC, Offenhauser N, Di Fiore PP, Knipper M, Masetto S & Marcotti W
Eps8 Regulates Hair Bundle Length and Functional Maturation of Mammalian Auditory Hair Cells.
PloS Biology 2011. 9: e1001048.
Kuhn S, Johnson SL, Furness DN, Chen J, Ingham N, Hilton JM, Steffes G, Lewis MA, Zampini V, Hackney CM, Masetto S, Holley MC, Steel KP & Marcotti W
miR-96 regulates the progression of differentiation in mammalian cochlear inner and outer hair cells.
Proc Natl Acad Sci USA 108:2355-60.
Johnson SL, Franz C, Kuhn S, Furness DN, Rüttiger L, Münkner S, Rivolta MN, Seward EP, Herschman HR, Engel J, Knipper M & Marcotti W (2010)
Synaptotagmin IV determines the linear calcium dependence of vesicle fusion at auditory ribbon synapses.
Nature Neurosci 13:45-52.
Marcotti W and Masetto S (2010)
Hair Cells.
In: Encyclopedia of Life Sciences (ELS). John Wiley & Sons, Ltd: Chichester. DOI: 10.1002/9780470015902.a0000181.pub2. (Review)
Miller G
Miller G, Neilan M, Chia R, Gheryani N, Holt N, Charbit A, Wells S, Tucci V, Lalanne Z, Denny P, Fisher EMC, Cheeseman M, Askew GN and Dear TN.
ENU Mutagenesis Reveals a Novel Phenotype of Reduced Limb Strength in Mice Lacking Fibrillin 2.
PLoS ONE. 2010. 5, e9137.
Milo M
Chen W, Jongkamonwiwat N, Abbas L, Eshtan SJ, Johnson SL, Kuhn S, Milo M, Thurlow JK, Andrews PW, Marcotti W, Moore HD, Rivolta MN (2012, September 12).
Restoration of auditory evoked responses by human ES-cell-derived otic progenitors.
Nature. doi:10.1038/nature11415
Knuckles, P., Vogt, M. A., Lugert, S., Milo, M., Chong, M. M. W., Hautbergue, G. M., . . . Taylor, V. (2012).
Drosha regulates neurogenesis by controlling Neurogenin 2 expression independent of microRNAs.
Nature Neuroscience, 15(7), 962-969. DOI
Rothman, A. M. K., Morton, A. C., Chico, T. J., Crossman, D. C., & Milo, M. (2011, October).
PERIPHERAL WHOLE BLOOD MICRORNA SIGNATURE DIFFERENTIATES BETWEEN MYOCARDIAL INFARCTION AND UNSTABLE ANGINA.
HEART, 97(20), 7. doi:10.1136/heartjnl-2011-300920b.16
Honkela, A., Milo M., Holley, M., Rattray, M., & Lawrence, N. D. (2010).
Ranking of gene regulators through differential equations and Gaussian processes.
In Proceedings of the 2010 IEEE International Workshop on Machine Learning for Signal Processing, MLSP 2010 (pp. 154-159).
Ward JR, Heath PR, Catto JW, Whyte MK, Milo M, Renshaw SA.
Regulation of neutrophil senescence by microRNAs.
PLoS One. 2011 Jan 19;6(1):e15810.
Bina S, Wright VM, Fisher KH, Milo M, Zeidler MP.
Transcriptional targets of Drosophila JAK/STAT pathway signalling as effectors of haematopoietic tumour formation.
EMBO Rep. 2010 Mar;11(3):201-
Chico TJ, Milo M, Crossman DC.
The genetics of cardiovascular disease: new insights from emerging approaches.
J Pathol. 2010 Jan;220(2):186-97. Review.
Moore H
Mohanty ST, Cairney CJ, Chantry AD, Madan S, Fernandes JA, Howe SJ, Moore HD, Thompson MJ, Chen B, Thrasher A, Keith WN, Bellantuono I.
A Small Molecule Modulator of Prion Protein Increases Human Mesenchymal Stem Cell Lifespan, Ex Vivo Expansion, and Engraftment to Bone Marrow in NOD/SCID Mice.
Stem Cells. 2012 Jun;30(6):1134-43. doi: 10.1002/stem.1065.
Mossman JA, Slate J, Birkhead TR, Moore HD, Pacey AA.
Mitochondrial haplotype does not influence sperm motility in a UK population of men.
Hum Reprod. 2012 Mar;27(3):641-51. Epub 2012 Jan 2.
Barbaric I, Jones M, Buchner K, Baker D, Andrews PW, Moore HD.
Pinacidil enhances survival of cryopreserved human embryonic stem cells.
Cryobiology. 2011 Dec;63(3):298-305. Epub 2011 Oct 17.
Plews JR, Li J, Jones M, Moore HD, Mason C, Andrews PW, Na J.
Activation of pluripotency genes in human fibroblast cells by a novel mRNA based approach.
PLoS One. 2010 Dec 30;5(12):e14397.
Udayashankar R, Baker D, Tuckerman E, Laird S, Li TC, Moore HD.
Characterization of invasive trophoblasts generated from human embryonic stem cells.
Hum Reprod. 2011 Feb;26(2):398-406. Epub 2010 Dec 16.
Amps KJ, Jones M, Baker D, Moore HD.
In situ cryopreservation of human embryonic stem cells in gas-permeable membrane culture cassettes for high post-thaw yield and good manufacturing practice.
Cryobiology. 2010 Jun;60(3):344-50. Epub 2010 Mar 27.
Nassar MA
Zhao J, Yuan G, Cendan CM, Nassar MA, Lagerstrom MC, Kullander K, Gavazzi I, Wood JN.
Nociceptor-expressed ephrin-B2 regulates inflammatory and neuropathic pain.
Mol Pain. 2010 Nov 8;6(1):77. [Epub ahead of print]
Zhao J, Lee MC, Momin A, Cendan CM, Shepherd ST, Baker MD, Asante C, Bee L, Bethry A, Perkins JR, Nassar MA, Abrahamsen B, Dickenson A, Cobb BS, Merkenschlager M, Wood JN.
Small RNAs control sodium channel expression, nociceptor excitability, and pain thresholds.
J Neurosci. 2010 Aug 11;30(32):10860-71.
Golden JP, Hoshi M, Nassar MA, Enomoto H, Wood JN, Milbrandt J, Gereau RW 4th, Johnson EM Jr, Jain S.
RET signaling is required for survival and normal function of nonpeptidergic nociceptors.
J Neurosci. 2010 Mar 17;30(11):3983-94.
Eijkelkamp N, Heijnen CJ, Willemen HL, Deumens R, Joosten EA, Kleibeuker W, den Hartog IJ, van Velthoven CT, Nijboer C, Nassar MA, Dorn GW 2nd, Wood JN, Kavelaars A.
GRK2: a novel cell-specific regulator of severity and duration of inflammatory pain.
J Neurosci. 2010 Feb 10;30(6):2138-49.
Placzek M
FGF-dependent midline-derived progenitor cells in hypothalamic infundibular development.
Pearson CA, Ohyama K, Manning L, Aghamohammadzadeh S, Sang H, Placzek M.
Development. 2011 138:2613-24.
FatJ acts via the Hippo mediator Yap1 to restrict the size of neural progenitor cell pools.
Van Hateren NJ, Das RM, Hautbergue GM, Borycki AG, Placzek M, Wilson SA.
Development. 2011 138:1893-902.
Rashbass P
Boroviak T, Rashbass P.
The apical polarity determinant Crumbs 2 is a novel regulator of ESC-derived neural progenitors.
Stem Cells. 2011 29(2):193-205. doi: 10.1002/stem.567.
Renshaw SA
David J Wardle, Joseph Burgon, Ian Sabroe, Colin D Bingle, Moira KB Whyte, Stephen A Renshaw
Effective caspase inhibition blocks neutrophil apoptosis and reveals Mcl-1 as both a regulator and a target of neutrophil caspase activation.
PLoS ONE 2011 6(1) e15768
Jon R. Ward, Paul R. Heath, Marta Milo, James W. Catto, Moira K.B. Whyte, Stephen A. Renshaw.
Regulation of Neutrophil Senescence by MicroRNAs.
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