The University of Sheffield
Department of Biomedical Science

Neuroscience and Neurodegenerative Disease

Neuroscience and Neurodegenerative Disease

Our research embraces:

  1. the development of the nervous system, from the specification, patterning and function of embryonic, adult and induced neural stem cells through to the formation and maintenance of functional neuronal networks;
  2. the physiology and pharmacology of neuronal microcircuits devoted to sensory, motor and cognitive function;
  3. diseases affecting the sensory, motor and cognitive aspects of the nervous system including pain syndromes, hearing disorders, Parkinson's disease and schizophrenia;
  4. development of novel nanoparticle, small molecule, genetic and brain-machine interface therapies for the treatment of neurological and psychiatric diseases.
Principal Investigator
Research Area
Dr. Beppe Battaglia Bionanotechnology and physical biology
Dr. Gordon Cooper Transport of gases and urea by membrane proteins
Dr.Vincent Cunliffe Development of the zebrafish central nervous system
Dr. Andrew Furley Role of L1-related cell adhesion molecules in neural development in mammals
Professor David Grundy Neurogastroenterology – the neural control of gut function
Professor Matthew Holley Development of the mammalian inner ear

Professor Mikko Juusola

Neural information processing from molecules to networks
Dr. Walter Marcotti Development of mammalian cochlear hair cells
Dr. Mohammed Nasser Role of sodium channels in chronic pain
Professor Marysia Placzek Ventralisation of the embryonic central nervous system
Dr. Penny Rashbass Apical-basal polarity in vertebrate development and disease
Dr Marcelo Rivolta The biology of auditory stem cells
Dr. Louise Robson Role of ion channels in epithelial health and disease
Dr. Elizabeth Seward Ion channels, receptors and regulation of exocytosis
Professor Elizabeth Smythe Regulation of membrane trafficking
Dr. Tanya Whitfield Development of the fish inner ear
Dr. Alex Whitworth Drosophila models of neurodegeneration