Dr Tanya Whitfield: Publications
Buck LMJ, Redfern WS, Winter MJ and Whitfield TT
Ototoxin-induced cellular damage in neuromasts disrupts lateral line function in larval zebrafish.
Hearing Research. 2012 in press.
Hammond KL, Whitfield TT
Fgf and Hh signalling act on a symmetrical pre-pattern to specify anterior and posterior identity in the zebrafish otic placode and vesicle.
Development. 2011. 138:3977-87.
Abbas L, Hajihashemi S, Stead LF, Cooper GJ, Ware TL, Munsey TS, Whitfield TT, White SJ.
Functional and developmental expression of a zebrafish Kir1.1 (ROMK) potassium channel homologue Kcnj1.
J Physiol. 2011 Mar 15;589(Pt 6):1489-503.
Hammond KL, van Eeden FJ, Whitfield TT.
Repression of Hedgehog signalling is required for the acquisition of dorsolateral cell fates in the zebrafish otic vesicle.
Development. 2010. 137, 1361-1371.
Abbas L, Whitfield TT (2009).
Nkcc1 (Slc12a2) is required for the regulation of endolymph volume in the otic vesicle and swim bladder volume in the zebrafish larva.
Development 136, 2837-48.
Hammond KL, Whitfield TT (2009).
Expression of zebrafish hip: Response to Hedgehog signalling, comparison with ptc1 expression, and possible role in otic patterning.
Gene Expr Patterns 9, 391-6.
Hammond, K. L., Loynes, H. E., Mowbray, C., Runke, G., Hammerschmidt, M., Mullins, M. C., Hildreth, V., Chaudhry, B. and Whitfield, T. T. (2009)
A Late Role for bmp2b in the Morphogenesis of Semicircular Canal Ducts in the Zebrafish Inner Ear.
PLoS ONE, 4, e4368
Dutton, K., Abbas, L., Spencer, J., Brannon, C., Mowbray, C., Kelsh, R. N. and Whitfield, T. T. (2009).
A zebrafish model for Waardenburg syndrome type IV reveals diverse roles for Sox10 in the otic vesicle.
Disease Models and Mechanisms 2, 68-83.
Hammond, K. L., Baxendale, S., McCauley, D. W., Ingham, P. W. and Whitfield, T. T. (2009).
Expression of patched, prdm1 and engrailed in the lamprey somite reveals conserved responses to Hedgehog signalling.
Evol. Dev. 11, 27-41
Whitfield TT, Hammond KL (2007)
Axial patterning in the developing vertebrate inner ear.
Int J Dev Biol. 51:507-20.
Hammond, K. L. and Whitfield, T. T. (2006)
The developing lamprey ear closely resembles the zebrafish otic vesicle: otx1 expression can account for all major patterning differences.
Development 133, 1347-1357.
Kozlowski, D. J., Whitfield, T. T., Hukriede, N. A. and Weinberg, E. S. (2005)
The zebrafish dog-eared mutation disrupts eya1, a gene required for cell survival and differentiation in the inner ear and lateral line.
Developmental Biology 277: 27-41
Katherine L. Hammond, Helen E. Loynes, Amos A. Folarin, Joanne Smith and Tanya T. Whitfield (2003)
Hedgehog signalling is required for correct anteroposterior patterning of the zebrafish otic vesicle.
Development 130: 1403-1417
Katherine Hammond, Robert Hill, Tanya T. Whitfield, and Peter Currie (2002)
Isolation of three zebrafish dachshund homologues and their expression in sensory organs, the central nervous system and pectoral fin buds. Mechanisms of Development 112: 183-189
Catriona Mowbray, Matthias Hammerschmidt, and Tanya Whitfield (2001)
Expression of BMP signalling pathway members in the developing zebrafish inner ear and lateral line.
Mechanisms of Development 108: 179-184
Catherine Haddon, Catriona Mowbray, Tanya Whitfield, Daniel Jones, Stephen Gschmeissner, and Julian Lewis (1999)
Hair cells without supporting cells: further studies in the ear of the zebrafish mind bomb mutant.
Journal of Neurocytology 28: 837-850
Parichy D M, Rawls J F, Pratt S J, Whitfield T T and Johnson S L (1999)
Zebrafish sparse corresponds to an orthologue of c-kit and is required for the morphogenesis of a subpopulation of melanocytes, but is not essential for hematopoiesis or primordial germ cell development.
Development 126: 3425-3436
Whitfield T T, Granato M, van Eeden F J, Schach U, Brand M, Furutani-Seiki M, Haffter P, Hammerschmidt M, Heisenberg C P, Jiang Y J, Kane D A, Kelsh R N, Mullins M C, Odenthal J and Nuesslein-Volhard C (1996)
Mutations affecting development of the zebrafish inner ear and lateral line.
Development 123: 241-254
Whitfield, T. T., Heasman, J. and Wylie, C. C. (1995)
Early embryonic expression of XLPOU-60, a Xenopus POU-domain protein.
Developmental Biology 169, 759-769.
Whitfield, T. T., Sharpe, C. R. and Wylie. C. C. (1994)
Nonsense-mediated mRNA decay in Xenopus oocytes and embryos.
Developmental Biology 165, 731-734.
Whitfield, T., Heasman, J. and Wylie, C. (1993)
XLPOU-60, a Xenopus POU-domain mRNA, is oocyte-specific from very early stages of oogenesis and localised to presumptive mesoderm and ectoderm in the blastula.
Developmental Biology 155, 361-370.
Reviews and other publications
Whitfield, T. T. and Hammond, K. L. (2007)
Axial patterning in the developing vertebrate inner ear.
Int. J. Dev. Biol. Special Issue: Ear Development (eds. F. Giráldez and B. Fritzsch)
51, 507-520. [Review]
Whitfield, T. T. (2005)
Lateral line: precocious phenotypes and planar polarity.
Current Biology 15, R67-70.
Whitfield, T. T., Mburu, P., Hardisty-Hughes, R. E. and Brown, S. D. M. (2005)
Models of congenital deafness: mouse and zebrafish.
Drug Discovery Today: Disease Models
2, 85-92. [Review]
Tanya T. Whitfield (2002)
Zebrafish as a model for hearing and deafness.
Journal of Neurobiology 53: 157-171
Tanya T. Whitfield, Bruce B. Riley, Ming-Yung Chiang, and Bryan Phillips (2002)
Development of the zebrafish inner ear.
Developmental Dynamics 223: 427-458
Tanya Whitfield (2000)
The Zebrafish Anatomical Dictionary. Entry on ear, sensory patches, hair cells, semicircular canals, otoliths, statoacoustic ganglion and lateral line.
ZFIN
Whitfield T, Haddon C and Lewis J (1997)
Intercellular signals and cell-fate choices in the developing inner ear: origins of global and of fine-grained pattern.
Seminars in Cell and Developmental Biology
8: 239-247