Dr. Paul Armitage

Lecturer in MRI Physics

Address:
Academic Unit of Radiology
University of Sheffield
C Floor
Royal Hallamshire Hospital
Sheffield
S10 2JF
UK

Telephone: +44 (0) 114 226 5379
Fax: +44 (0) 114 271 1714
Email: p.armitage@sheffield.ac.uk

Biography:

I joined the Academic Unit of Radiology at the University of Sheffield in 2011 as a Lecturer in MRI Physics, having previously worked in Medical Image Analysis at the University of Edinburgh and University of Oxford.

Research Interests:

My primary research interest is in the development of post-processing methods for quantification of MRI data. In particular, for techniques such as diffusion tensor imaging, dynamic contrast-enhanced MRI, arterial spin labelling, image registration, MR signal modelling and their application to stroke, brain tumours, epilepsy and small vessel disease. My imaging interests span the entire age range from the foetus through to the ageing population.

Current Projects:

• Arterial Spin Labelling and DCE-MRI for perfusion measurement in paediatric neuroimaging.
• Methods for improving detection and surgical planning in Epilepsy.
• Quantitative diffusion tractography in neuroimaging.
• Developing MR imaging for measurements in bone.
• Permeability imaging in small vessel disease.

Key Publications:

1. PA Armitage, AJ Farrall, TK Carpenter, F Doubal, JM Wardlaw. Use of dynamic contrast enhanced MRI to measure subtle blood-brain barrier abnormalities. Magnetic Resonance Imaging 29(3), 305-314 (2011).


2. PA Armitage, C Schwindack, ME Bastin, IR Whittle. Pre-treatment tumoural perfusion correlates with response to dexamethasone in patients with glioblastom multiforme. Journal of Neurology, Neurosurgery, and Psychiatry 81(4), 446-448 (2010).


3. JM Wardlaw, F Doubal, P Armitage, F Chappell, T Carpenter, S Munoz Maniega, A Farrall, C Sudlow, M Dennis, B Dhillon. Lacunar stroke is associated with diffuse blood-brain barrier dysfunction. Ann Neurol 65(2), 194-202 (2009).


4. JM Wardlaw, A Farrall, PA Armitage, F Doubal, D Chowdhury, V Cvoro, T Carpenter, MS Dennis. Changes in background blood-brain barrier integrity between lacunar and cortical ischemic stroke subtypes. Stroke 39(4), 1327- 1332 (2008).


5. S Muñoz Maniega, ME Bastin, PA Armitage. Effects of random subject rotation on optimised diffusion gradient sampling schemes in diffusion tensor MRI. Magnetic Resonance Imaging 26(4), 451-460 (2008).


6. PA Armitage, C Schwindack, ME Bastin, IR Whittle. Quantitative assessment of intracranial tumour response to dexamethasone using diffusion, perfusion and permeability magnetic resonance imaging. Magnetic Resonance Imaging 25(3), 303-310 (2007).


7. B Karaszewski, JM Wardlaw, I Marshall, V Cvoro, K Wartolowska, K Haga, PA Armitage, ME Bastin, MS Dennis. Measurement of brain temperature with MR spectroscopy in acute ischaemic stroke. Annals of Neurology 60(4), 438-446 (2006).


8. TK Carpenter, PA Armitage, ME Bastin, JM Wardlaw. DSC Perfusion MRI – quantification and reduction of systematic errors arising in areas of reduced cerebral blood flow. Magnetic Resonance in Medicine 55(6), 1342-1349 (2006).


9. P Armitage, C Behrenbruch, M Brady, N Moore. Extracting and visualizing physiological parameters using dynamic contrast-enhanced magnetic resonance imaging of the breast. Medical Image Analysis 9(4), 315-329 (2005).

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