The University of Sheffield
Department of Cardiovascular Science

Professor Rod Hose BSc PhD

Professor of Computational Biomechanics

Professor Rodney Hose

Department of Cardiovascular Science
Medical Physics Group
University of Sheffield
Medical School
Beech Hill Road
Sheffield
S10 2RX

Telephone: 0114 27 13147
Fax: 0114 271 3403
Email: d.r.hose@sheffield.ac.uk

Biography:

After graduating in Mathematics from the University of Manchester, I joined Lucas Aerospace as a graduate apprentice engineer. From 1977 to 1992 I worked as a stress engineer and as a consultant structural analyst for several companies in the aerospace, motor vehicle and general engineering sectors. During this period I also completed my PhD in Applied Mechanics at the University of Manchester Institute of Science and Technology. I joined acadaemia in 1992 as a lecturer in Aircraft Structures at the University of Salford. I moved to Medical Physics at the University of Sheffield in 1994, where I was initially responsible for the development of undergraduate teaching in medical physics and had a primary research interest in the computational analysis of heart valve prostheses.

I am currently a Professor in Computational Biomechanics in the Medical Physics Group in the Department of Cardiovascular Science and hold an Honorary Contract with Sheffield Teaching Hospitals Foundation Trust.

Research Interests:

My research interests are in the development of methods and workflows for the computational analysis of (primarily) cardiovascular systems, and in their translation to clinical application. I am interested in all aspects of the process, from clinical data collection and management through image processing to build detailed three dimensional models of the vasculature and on to determination of appropriate boundary conditions, numerical solution and data reduction. I have been intimately involved in the development of the European Commission´s Virtual Physiological Human initiative from its beginning.

Teaching Interests:

I teach an undergraduate module in Biomechanics and Biofluid Mechanics, and supervise level three and level four projects for physics and engineering students.

Current Projects:

Recent Publications:

  1. Shi Y, Lawford PV, Hose DR. Numerical Modeling of haemodynamics with pulsatile impeller pump support. Annals of Biomedical Engineering. 38: 8; 2621, 2010.
  2. Singh PK, Marzo A, Howard B, Rufenacht DA, Bijlenga P, Frangi AF, Lawford PV, Coley SC, Hose DR, Patel UJ. Effects of smoking and hypertension on wall shear stress and oscillatory shear index at the site of intracranial aneurysm formation. Clin Neurol Neurosurg. 112(4):306-13, 2010.
  3. Singh PK, Marzo A, Coley SC, Berti G, Bijlenga P, Lawford PV, Villa-Uriol MC, Rufenacht DA, McCormack KM, Frangi A, Patel UJ, Hose DR., The role of computational fluid dynamics in the management of unruptured intracranial aneurysms: a clinicians’ view. Computational Intelligence and Neuroscience 760364. Epub 2009 Aug 19.
  4. Marzo A, Singh P, Reymond P, Stergiopulos N, Patel U, Hose DR. Influence of inlet boundary conditions on the local haemodynamics of intracranial aneurysms. Computer Methods in Biomechanics and Biomedical Engineering, 1476-8259; 12(4):431-444, 2009.
  5. Hand AJ, Sun T, Barber DC, Hose DR, MacNeil S. Automated tracking of migrating cells in phase-contrast video microscopy sequences using image registration. J Microsc. ;234(1):62-79, 2009.
  6. Narracott AJ, John GW, Morris RJ, Woodcock JP, Hose DR, Lawford PV. A validated model of calf compression and deep vessel collapse during external cuff inflation. IEEE Trans Biomed Eng. 56(2):273-80, 2009.
  7. Evans DJ, Lawford P, Gunn J, Walker D, Hose DR, Smallwood RH, Chopard B, Krafczyk M, Bernsdorf J, Hoekstra A. The application of multiscale modelling to the process of development and prevention of stenosis in a stented coronary artery. Philos Transact A Math Phys Eng Sci. Sep 28;366(1879):3343-60, 2008.
  8. Zervides C, Narracott AJ, Lawford PV, Hose DR. The role of venous valves in pressure shielding. Biomedical Engineering Online 7(1): 8, 2008.
  9. Diaz-Zuccarini, V; Hose, DR; Lawford, PV, et al. Multiphysics and multiscale simulation: Application to a coupled model of the left ventricle and a mechanical heart valve. International Journal for Multiscale Computational Engineering; 6(1): 65-76, 2008.
  10. Barber DC, Oubel E, Frangi AF, Hose DR. Efficient Computational Fluid Dynamics Mesh Generation by Image Registration. Medical Image Analysis, 11(6):648-662, 2007.
  11. Harrison SE, Smith SM, Bernsdorf J, Hose DR, Lawford PV. Application and Validation of the Lattice Boltzmann Method for Modelling Flow-Related Clotting. Journal of Biomechanics; 40(13): 3023-3028, 2007.
  12. Jeays AD, Lawford PV, Gillott R, Spencer P, Bardhan KD, Hose DR. Characterisation of the Haemodynamics of the Superior Mesenteric Artery. Journal Biomechanics; 40(9): 1916-26, 2007.
  13. Tanner C, Schnabel JA, Hill DL, Hawkes DJ, Degenhard A, Leach MO, Hose DR, Hall-Craggs MA, Usiskin SI. Quantitative evaluation of free-form deformation registration for dynamic contrast-enhanced MR mammography. Med Phys, 34(4):1221-1233, 2007.
  14. Hose DR, Narracott AJ, Penrose JMT, Baguley D, Jones I, Lawford PV, Fundamental mechanics of aortic valve closure, Journal Biomechanics, 39(5):958-967, 2006.

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