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Welcome to ChELSI, Chemical Engineering at the Life Science Interface.About ChELSI
ChELSI is an interdisciplinary institute founded to enhance interactions between chemical engineers and biologists across strategically important research themes. The Institute was established with a £4.3m EPSRC grant awarded in 2006.
This has funded a brand-new, 1500m2 building within the Department of Chemical and Biological Engineering at the University of Sheffield. The aim of ChELSI is to revolutionise the way in which life science research is conducted by adopting approaches from chemical engineering, and to exploit advances in biology to improve engineering processes.
Our Facilities
ChELSI research is founded upon state-of-the-art analytical methods and expertise available within the Institute and is performed in fully-equipped, custom-built molecular and microbiology laboratories. Find out more
Our Research
The Institute provides the space and facilities to enable chemical engineers and life scientists to collaborate on research in four key sectors:
WaterMicrobiology in urban water systems
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EnergyNew fuels from Biology
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BiomanufacturingOptimising cell factories for the biotechnology industry
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Medicines InterfaceEngineering insights to understand disease
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Researchers in ChELSI explore the role of microbiology in producing clean drinking water and treating waste and are setting out future uses for microbes engineered through synthetic biology.
As we move away from fossil fuels the energy portfolio of the future must become more diverse. In ChELSI new energy sources from biology are being developed, from microbial fuel cells to algal biodiesel.
Biomanufacturing harnesses the power of cells to synthesise chemicals for industry. In ChELSI improved microbial and mammalian cell culture systems are being developed.
Modern medicine increasingly considers disease in the context of a mis-functioning complex biological system. To address this complexity ChELSI interacts with medical researchers to bring an engineering approach to understanding disease.