Professor Paul V Hatton BSc PhD
Professor of Biomaterials Science and Honorary Non-Clinical Investigator
Tel: +44 (0) 114 271 7938
Fax: +44 (0) 114 226 5484
Email: paul.hatton@sheffield.ac.uk
Administrative Roles
Local
Head of the Biomaterials Research Group
Member of School Research Committee
Member of School Strategic Advisory Committee
Knowledge Transfer Champion (HEIF3)
National
President of the UK Society for Biomaterials (2004-2007)
Management committee of the Health Technologies Knowledge Transfer Network
Member of Biomedical Applications Division of the Institute of Materials, Minerals & Mining (IoM3)
International
Chair of the EXPERTISSUES FP6 Network of Excellence Education & Training Committee
Member of Steering Committee for EXPERTISSUES Network of Excellence
International Organising Committee for European Chapter meeting of Tissue Engineering & Regenerative Medicine International Society (TERMIS-EU 2008), Porto
Editorial Board, Journal of Tissue Engineering & Regenerative Medicine
Research Interests
Professor Hatton has interests in biomaterials, medical devices and tissue engineering for clinical applications in human skeletal tissues. The five major themes for his research are (1) the development of bioactive glasses and ceramics for mineralised tissue repair, (2) glass-ionomer bone cements, (3) In vitro evaluation of biocompatibility, and (4) Cartilage and bone tissue engineering on biomaterial scaffolds. He is also active more broadly in the promotion of academic-industrial collaboration and technology transfer in the orthopaedic, craniofacial and dental material sectors. See "Links" below for more details on this and the wider research of the Biomaterials Research Group.
Recent Publications (2003-2008)
K. HURRELL-GILLINGHAM, I. M. REANEY, C.A.MILLER, A. CRAWFORD & P.V.HATTON. 2003. Devitrification of ionomer glass and its effect on the in vitro biocompatibility of glass-ionomer cements. Biomaterials 24, 3153-3160.
FREEMAN, C. O., BROOK, I. M., JOHNSON, A., HATTON, P. V., STANTON, K. T., & HILL, R. G. 2003. Crystallization modified osteoconductivity in an apatite-mullite glass-ceramic. Journal of Materials Science: Materials in Medicine 14, 1-6.
JOHNSON, A., VAN NOORT, R., HATTON, P. V. & WALSH, J. M. 2003. The effect of investment material and ceramming regime on the surface roughness of two castable glass-ceramic materials. Dental Materials 19, 218-225.
SCOTT, A., GAWKRODGER, D. J., YEOMAN, C., EGNER, W., VAN NOORT, R., HATTON, P. V., AND GRUMMITT, J. 2003. Adverse Reactions to Protective Gloves used in the Dental Profession: Experience of the UK Adverse Reaction Reporting Project. British Dental Journal 195(12), 686-690.
SCOTT A., EGNER W., GAWKRODGER D.J., HATTON P.V., SHERRIFF M., VAN NOORT R., YEOMAN C., GRUMMITT J. 2004. The national survey of adverse reactions to dental materials in the UK: a preliminary study by the UK Adverse Reactions Reporting Project. British Dental Journal 196(8), 471-7.
MILLER, C.A., REANEY, I.M., HATTON, P.V. AND JAMES, P.F. 2004. Crystallisation of canasite/frankamenite-based glass-ceramics. Chemistry of Materials 16(26), 5736-5743.
MIRSANEH, M., REANEY, I. M., HATTON, P. V., AND JAMES, P. F. 2004. Characterization of High-Fracture Toughness K-Fluorrichterite-Fluorapatite Glass Ceramics. Journal of the American Ceramic Society 87(2), 240-246.
KANCHANARAT N., MILLER C.A., HATTON P.V., JAMES P.F., REANEY I.M. 2005. Early stages of crystallization in canasite-based glass ceramics. Journal of the American Ceramics Society 88(11), 3198-3204.
HURRELL-GILLINGHAM, K., REANEY, I.M., BROOK, I. M. AND HATTON, P.V. 2005. Novel Fe2O3-containing glass-ionomer cements: Glass characterisation. Key Engineering Materials 284-286, 799-802.
MIRSANEH, M., REANEY, I. M., JAMES, P. F. AND HATTON P. V. 2006. Effect of CaF2 and CaO substituted for MgO on the phase evolution and mechanical properties of K-fluoricterite glass ceramics. Journal of the American Ceramic Society 89 (2), 587-595.
BANDYOPADHYAY-GHOSH, S., I.M. REANEY, A. JOHNSON, K. HURRELL-GILLINGHAM, I.M. BROOK, and P.V. HATTON. 2006. Castability and biocompatibility of novel fluorcanasite glass-ceramics. Key Engineering Materials 309-311, 293-296.
AL-SALEHI, S.K., HATTON, P.V., MILLER, C.A., MCLEOD, C. AND JOINER, A. 2006. The effect of carbamide peroxide treatment on metal ion release from dental amalgam. Dental Materials, 22(10), 948-953.
HURRELL-GILLINGHAM K.E., REANEY I.M., BROOK I. AND HATTON P.V. 2006. In vitro biocompatibility of a novel Fe2O3 based glass ionomer cement. Journal of Dentistry, 34(8), 533-538.
HATTON PV, HURRELL-GILLINGHAM K, BROOK IM. 2006. Biocompatibility of glass-ionomer bone cements. Journal of Dentistry 34(8): 598-601
FRASER, S.A., CRAWFORD, A., FRAZER, A., DICKINSON, S., HOLANDER A.P. AND HATTON, P.V. 2006. Localization of type VI collagen in tissue engineered cartilage. Tissue Engineering, 12(3), 569-577.
S. BANDYOPADHYAY-GHOSH, I.M. REANEY, I.M. BROOK, K. HURRELL-GILLINGHAM, A. JOHNSON, P.V. HATTON. 2007. In vitro biocompatibility of fluorcanasite glass-ceramics for bone tissue repair. Journal of Biomedical Materials Research Volume 80A(1), 175 – 183.
AL-SALEHI, S.K., HATTON, P.V., MCLEOD, C. AND COX, A. G. 2007. The effect of hydrogen peroxide concentration on metal ion release from dental amalgam. Journal of Dentistry, 35(2):172-6.
AL-SALEHI S.K., WOOD D.J., HATTON P.V. 2007. The effect of 24h non-stop hydrogen peroxide concentration on bovine enamel and dentine mineral content and microhardness. Journal of Dentistry 35(11):845-50.
JOHN COLLETT, J., CRAWFORD, A. HATTON, P. V., GEOGHEGAN, M., AND RIMMER. S. 2007. Thermally responsive polymeric hydrogel brushes: synthesis, physical properties and use for the culture of chondrocytes. Journal of The Royal Society Interface, 4 117-126.
OLIVEIRA J.T., CRAWFORD A., MUNDY J.M., MOREIRA A.R., GOMES M.E., HATTON P.V., REIS R.L. 2007. A cartilage tissue engineering approach combining starch-polycaprolactone fibre mesh scaffolds with bovine articular chondrocytes. Journal of Materials Science: Materials in Medicine 18(2):295-302
KELLY DJ, CRAWFORD A, DICKINSON SC, SIMS TJ, MUNDY J, HOLLANDER AP, PRENDERGAST PJ, HATTON PV. 2007. Biochemical markers of the mechanical quality of engineered hyaline cartilage. Journal of Materials Science: Materials in Medicine 18(2):273-81.
PLAINFOSSÉ M., HATTON P.V., CRAWFORD A., JIN Z.M., FISHER J. 2007. Influence of the extracellular matrix on the frictional properties of tissue-engineered cartilage. Biochemical Society Transactions 35(Pt 4):677-9
AL-SALEHI SK, HATTON PV, JOHNSON A, COX AG, MCLEOD C. 2008. The effect of hydrogen peroxide concentration on metal ion release from dental casting alloys. Journal of Oral Rehabilitation 35(4):276-82.
BANDYOPADHYAY-GHOSH S, REANEY IM, JOHNSON A, HURRELL-GILLINGHAM K, BROOK IM, HATTON PV. 2008. The effect of investment materials on the surface of cast fluorcanasite glasses and glass-ceramics. Journal of Materials Science: Materials in Medicine 19(2):839-46
MACINTOSH AC, KEARNS VR, CRAWFORD A, HATTON PV. 2008. Skeletal tissue engineering using silk biomaterials. Journal of Tissue Engineering and Regenerative Medicine 2(2-3):71-80
Postgraduate Research Students (2006 -)
Ana MacIntosh (EC), "Evaluation of Silk-Based Scaffolds for Tissue Engineering". Co-supervised by Dr Aileen Crawford.
Samira Al-Salehi* (staff candidiate) "The Effect of Tooth Bleaching Agents on Dental Biomaterials". Co-supervised by Professor Cameron McLeod.
Felora Merkavoly "Regenerative approaches to treating periodontal tissue loss" Primary supervisor is Professor Andrew Rawlinson.
Rebecca Goodchild (EPSRC DTA) "Scaffolds for osteochondral tissue engineering". Co-supervised by Professor Tony Ryan and Professor Ian Reaney.
Marie Plainfosse (White Rose Studentship) "Tribology and mechanical properties of tissue engineered cartilage". Co-supervised by Dr Aileen Crawford, Professor X Jin (Leeds) and Professor John Fisher (Leeds).
Agnieszka Kwarciak (EC Marie Curie) "Cell Sources for cartilage tissue engineereing". Primary supervisor is Dr Aileen Crawford.
Linda Elowsson* (EC Marie Curie) "Cell detachment from thermoresponsive surfaces". Co-supervised by Dr Aileen Crawford and Dr Steve Rimmer
Richard Ackbar* (EPSRC CASE studentship) "Porous ceramic scaffolds for tissue engineering". Co-supervised by Dr Kathryn Hurrell-Gillingham and Dr Aileen Crawford.
Shashwat Bhakta (staff candidate, SPR/HST) "Glass-ceramics for dental applications". Co-supervised by Professor Ian Brook, Professor Ric van Noort, Dr Tony Johnson and Dr Cheryl Miller.
Links
Bioengineering and Health Technologies Research Group
http://healthtech.globalwatchonline.com/epicentric_portal/site/healthtech/