Dr Stuart Hunt B.Sc.(Hons), M.Sc., Ph.D.
Non-clinical lecturer in Human Anatomy
Member of the Oral Disease Research Group
Tel: 0114 271 7963
Fax: 0114 271 7863
Email: S.hunt@sheffield.ac.uk
Teaching:
DEN 104 The Oral Cavity in Health and Disease
Research Interests:
Whilst studying for my PhD in the Department of Molecular Biology and Biotechnology in Sheffield, I mainly focused on transcriptional regulation of gene expression (promoter structure and contribution of transcription factors). Since joining the Unit of Oral & Maxillofacial Pathology, working as a post-doctoral researcher with Dr Daniel Lambert, I have developed an interest in regulation of gene expression and have amassed experience of analysing post-transcriptional regulation of gene expression in oral squamous cell carcinoma (OSCC), mediated by microRNAs. I hope to continue my molecular research into OSCC in the coming months.
Information for Prospective PhD Students
There are a number of possible PhD projects and enquiries from prospective students are welcome.
Recently published papers:
Hunt S, Jones AV, Hinsley EE, Whawell SA and Lambert DW (2010) MicroRNA-124 suppresses oral squamous cell carcinoma motility by targeting ITGB1. FEBS Lett. In press.
Hunt S, Green J and Artymiuk PJ (2010). Hemolysin E (HlyE, ClyA, SheA) and Related Toxins. Advances in Experimental Medicine and Biology, 677: 116-126.
Graham AI, Hunt S, Stokes SL, Bramall N, Bunch J, Cox AG, McLeod CW and Poole RK (2009). Severe zinc depletion of Escherichia coli: roles for high affinity zinc binding by ZinT, zinc transport and zinc-independent proteins. Journal of Biological Chemistry, 284(27): 18377-18389.
Ryan RM, Green J, Williams PJ, Tazzyman S, Hunt S, Harmey JH, Kehoe SC and Lewis CE (2009). Bacterial delivery of a novel cytolysin to hypoxic areas of solid tumors. Gene Therapy, 16(3): 329-339.
Hunt S, Moir AJ, Tzokov S, Bullough PA, Artymiuk PJ and Green J (2008). The formation and structure of Escherichia coli K-12 haemolysin E pores. Microbiology, 154: 633-642.
