Dr. Simon A. Whawell (BSc(Hons), PGDip Ed, FHEA, PhD)
Senior Lecturer in the Academic Unit of Oral & Maxillofacial Pathology
Academic Unit of Oral & Maxillofacial Pathology
The School of Clinical Dentistry
The University of Sheffield
19 Claremont Crescent
Sheffield
S10 2TA
Tel: 0114 271 7953
Fax: 0114 271 7894
email : s.whawell@sheffield.ac.uk
Administrative Role
Theme Leader DEN 103 (Human Body, 1st BDS)
Director of Post Graduate Taught (PGT) courses (2012-)
Chair PGT Working Party
Chair, Oral & Maxillofacial Pathology Unit Courses Review Committee
Dental School representative at Faculty of Medicine, Dentistry and Health PGT committee
National Administrative Role
Editorial Board member, Journal Oral Pathology & Medicine (2009-)
Chair awards committee & management committee member, British Society for Oral & Dental Research (2011-)
Member-at-large, Oral Medicine & Pathology Group, International association for Dental Research (2014-15)
Young investigator awards committee member (2010-2013), International Association for Dental Research
‘All about me’ Gallery development committee member, Eureka! National Children’s Museum, Halifax
Research Interests
Integrins, proteases and the extracellular matrix in the modification of epithelial cell behaviour, oral squamous cell carcinoma invasion in particular.
Epithelial-bacterial interactions, including mechanisms of bacterial invasion and strategies for killing intracellular bacteria
Recently Published Papers
Ridley RA, Douglas I, Whawell SA. Differential adhesion and invasion of epithelial cells derived from different anatomical sites by Staphylococcus aureus. Journal of Medical Microbiology 2012; 61: 1654-1661.
Hinsley EE, Kumar S, Hunter KD, Whawell SA, Lambert DW. Endothelin-1 stimulates oral fibroblasts to promote oral cancer invasion. Life Science 2012; 91: 557-561.
Hinsley EE, Hunt S, Hunter KD, Whawell S and Lambert DW. Endothelin-1 stimulates motility of head and neck squamous carcinoma cells by promoting stromal-epithelial interactions. International Journal of Cancer 2012; 130: 40-47.
Roy S, Bingle L, Marshall JF, Bass R, Ellis V, Speight PM, Whawell SA. The role of the α9β1 integrin in modulating epithelial cell behaviour. Journal of Oral Pathology and Medicine 2011; 40: 755-761
Hunt S, Jones AV, Hinsley EE, Whawell S and Lambert DW. MicroRNA-124 Suppresses Oral Squamous Cell Carcinoma Invasion by Targeting ITGB1. FEBS Letters 2011; 585: 187-192
Jenkinson S, Whawell SA, Swales BM, Corps E, Kilshaw P, Farthing PM. The αE(CD103)β7 integrin interacts with oral and skin keratinocytes in an E-cadherin-independent manner. Immunology 2011; 132: 188-196
Current MPhil/PhD Students
Nada Al-Hindi (PhD)
Personal Web Links:
http://www.sheffield.ac.uk/dentalschool/research/ibio/hostpath
http://www.sheffield.ac.uk/dentalschool/research/ibio/tum-inv