Dr Jerry Wales, DM, MA, BM BCh, MRCP, FRCPCH, DCH

Academic Unit of Child Health
Sheffield Children´s Hospital
Sheffield
S10 2TH
UK
Office: C17
Tel: +44 (0) 114 2717508
Fax: +44 (0) 114 275 5364
email: j.k.wales@sheffield.ac.uk
Biography
I trained at Oxford then held NHS posts in Oxford, Glasgow, Southampton and Sheffield. I joined the University of Sheffield in 1984 as a lecturer and was appointed Senior Lecturer and Honorary Consultant in Paediatric Endocrinology and Diabetes at the Children's Hospital in 1991. I spent a sabbatical year as Visiting Academic at the Institute of Adolescent Health, Melbourne in 2002.
Research Interests
My research interests relate to neonatal growth and it's sequelae, childhood obesity management, bone health in obesity, type 2 diabetes, adolescent diabetes and transition in Endocrinology.
Teaching Interests
I am assessed very highly for my lecturing skills and am frequently an invited speaker at National and International events. I was a Faculty member of the European Society for Paediatric Endocrinology and Diabetes Winter School for developing nations for 5 years until 2010, delivering the last course entirely in French. In Sheffield I teach on phase 1b, Phase 2 and 3 of the MB ChB course. I also teach on the MSc in Genetics Med6003, Molecular Genetics of Human Diseases.
Professional activities
I am a member of the Royal College of Paediatrics and Child Health, the British Society for Paediatric Endocrinology and Diabetes (BSPED), the European Society for Paediatric Endocrinology (ESPE), Diabetes UK & International Society for Paediatric and Adolescent Diabetes (ISPAD). I am an Executive Member Young People´s Health Special Interest Group (YPHSIG).
Current Projects
• Obesity – with the Centre for Sport & Exercise Science, Sheffield Hallam University – CLAHRC funded project
• Childhood Type 2 Diabetes – "JUMP" - MRC funded cohort study with Tim Barrett, Birmingham
• COMMEND study – endocrine transition – RfPB funded study with Prof Peter Callery, Manchester
• Adolescent Diabetes – CLAHRC funded study with Prof Simon Heller, Sheffield.
• Neonatal growth cohort – 16y cohort study, charity funded –now in 16th year.
• Kick-off – Deputy CI for national RCT of educational program for children with diabetes, led by Dr K Price in Sheffield, funded by Diabetes UK.
Key publications
Dimitri, P., Wales, J.K. and Bishop, N. (2010) Adipokines, bone-derived factors and bone turnover in obese children; evidence for altered fat-bone signalling resulting in reduced bone mass. Bone 48: 189-196.
Dimitri, P., Wales, J.K. and Bishop, N. (2010) Fat and Bone in Children: differential Effects of Obesity on Bone Size and Mass According to Fracture History. Journal of Bone and Mineral Research 25: 527-536.
Kapoor, R.R., Locke, J., Colclough, K., Wales, J., Conn, J.J., Hattersley, A.T., Ellard, S. and Hussain, K. (2008) Persistent hyperinsulinemic hypoglycemia and maturity-onset diabetes of the young due to heterozygous HNF4A mutation. Diabetes 57: 1659-1666.
Patel, L., Cavazzoni, E., Whatmore, A.J., Carney, S., Wales, J.K., Clayton, P.E., Gibson, A.T. (2007) The contributions of plasma IGF-I, IGFBP-3 and leptin to growth in extremely premature infants during the first two years. Pediatric Research 61: 99-104.
Daley, A.J., Copeland, R.J., Wright, N.P., Roalfe, A. and Wales, J.K. (2006) Exercise therapy as a treatment for psychopathology in obese and morbidly obese adolescents: randomised controlled trial. Pediatrics 118: 2126-2134.
Gloyn, A.L., Pearson, E.R., Antcliff, J.F., Proks, P., Bruining, G.J., Slingerland, A.S., Howard, N., Srinivasan, S., Silva, J.M.C.L., Molnes, J., Edghill, E.L., Frayling, T.M., Temple, I.K., Mackay, D., Shield, J.P.H., Sumnik, Z., van Rhijn, A., Wales, J.K.H., Clark, P., Gorman, S., Aisenberg, J., Ellard, S., Njølstad, P.R., Ashcroft, F.M., Hattersley, A.T. (2004) Permanent neonatal diabetes results from activating mutations in the pancreatic potassium channel subunit Kir 6.2 (KCNJ11). New England Journal of Medicine 350: 1838-1849.
