Professor Iain D Wilkinson BSc, MSc, PhD, CSci, ARCP, FIPEMIain Wilkinson

Professor of Magnetic Resonance Physics
Departmental Reward & Recognition Lead

Department of Infection, Immunity & Cardiovascular Disease
University MRI
C Floor
Royal Hallamshire Hospital
Sheffield
S10 2JF
UK

Tel: +44 (0)114 215 9606
Fax: +44 (0)114 271 1714
Email: i.d.wilkinson@sheffield.ac.uk
Secretary - Chrissie Gash
Tel: +44 (0)114 215 9507
Email: c.gash@sheffield.ac.uk

Biography:

I am Professor of Magnetic Resonance (MR) Physics and lead the adult neuroimaging research programme within the Academic Unit of Radiology, part of the University´s Medical School based at the Royal Hallamshire Hospital. I particularly enjoy the clinical applications of MR and as a UK state-registered Clinical Scientist, am an honorary Consultant with local NHS Trusts.

Prior to joining the University of Sheffield in 1997, I was an NHS physicist at The Middlesex Hospital (UCLH) and Addenbrooke´s Hospital in Cambridge. I obtained my Bachelors in Physics from the University of Lancaster, Masters in Radiation Physics from St Bartholomew´s Hospital Medical College and Doctorate in MR from the Royal Postgraduate Medical School (at Hammersmith Hospital, now part of Imperial College).

Research Interests:

I aim to further our understanding of neurological disease and thereby aid its diagnosis and treatment via in-vivo MR Imaging & Spectroscopy. The emphasis of this has always been on the translation of MR techniques and the findings of MR studies into clinical use. Clinical areas thus far concentrated on have included:

  • central nervous system involvement in Diabetes Mellitus
  • neurodegereration / the dementias
  • cerebrovascular
  • psychiatric diseases
  • neuro-oncology
  • retroviral infection/encephalopathies
  • abnormalities of the spino-cerebellar thalamic tracts

I'm also interested in the non-medical applications of MR particularly with respect to our understanding of the human mind.

I am indebted to the Wellcome Trust, Neurocare, Action for M.E, EAFD/Novo Nordisk, JDRF, Diabetes UK, EU, MRC, DH / NIHR, EPSRC, University of Sheffield Alumni, Ataxia UK, Sheffield Health & Social Research Consortium, Sheffield Hospital’s Charitable Trust, Leverhulme Trust, Pfizer IIR and Philips Healthcare for their financial help in support of collaborative imaging research.

Teaching Interests:

I supervise research projects for students undertaking BMedSci, MD and PhD projects. I am also an undergraduate tutor for students studying on Sheffield’s Medical Course.

Professional Activities:

In addition to being a Fellow of the Institute of Medical Physics & Engineering in Medicine (IPEM), I am currently a member of the IPEM´s MR Special Interest Group that organises scientific and educational meetings and deals with professional matters relating to the Institute´s involvement in MR Physics. I am an active member of the International Society of Magnetic Resonance in Medicine (ISMRM) and the British Chapter of the ISMRM that hold `cutting edge´ scientific meetings and symposia. I´m also a member of the British Institute of Radiology which is a forum for the multidisciplinary teams who are professionally involved or interested in medical imaging. When applying physics to medicine and clinical research, it is important to grasp an understanding what drives clinical problem solving and to link with the medical professionals involved. To this end, I am an Affiliate (non-clinical Fellow) of the Royal College of Physicians and an Associate of the British Society of NeuroRadiologists (BSNR). Since one of my main current interests is in `Diabetes and the Brain´, I am a Professional Member of Diabetes UK and a member of NeuroDiab and the European Association for the Study of Diabetes (EASD).

Current Projects:

  • Principle Investigator of a Wellcome Trust - funded replacement 3T human clinical research MR scanner within our Unit’s base at the Royal Hallamshire Hospital.
  • Cerebrovascular & cardiovascular autoregulatory dysfunction in Diabetes.
  • Arterial brain perfusion & the brain’s functional pain matrix in Diabetic Neuropathy.
  • Virtual Physiological Human modelling of the Dementias (VPH-DARE@IT).
  • Functional correlates of pain in Chemotherapy Induced Peripheral Neuropathy.
  • MR of muscle status in Amyotrophic Lateral Sclerosis (MND).
  • Post-exertion resting-state brain status in Myalgic Encephalopathy.
  • Brain function in schizophrenia (auditory hallucinations, emotion regulation and ‘tranquility’).
  • Cerebellar status in the ataxias & neuronal degenerative disorders.

Publications (out of 165 papers):

For key publications see below. For a full list of publications click here.

Journal articles