Information for and about MBB staff
For a list of all MBB staff see the phone book webpage.
New staff or current staff, please use the online form to Add and Update your staff details
This link also contains Induction and Safety details.
MBB Academic Staff Gallery
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Dr Roger Anderson - Director of Studies Genetic and molecular studies on the regulation of gene expression during development from amoeba to plasmodium in the slime mould Physarum polycephalum.
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Prof Pete Artymiuk Protein crystallography, protein folding and motifs, structural databases, structure refinement and analysis, solvent structure, molecular graphics.
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Prof Kathryn Ayscough Genetic, molecular and cell biological approaches in budding yeast to investigate the role of the actin cytoskeleton in endocytosis, apoptosis and ageing.
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Dr Patrick Baker Use of protein crystallography to study the structure/function relationships in biological macromolecules.
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Prof Mike Blackburn Mechanism of phosphoryl transfer in kinases; transition states and transition state analogues
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Prof Per Bullough Interests include structure of membrane proteins and complexes by high resolution electron microscopy and X-ray crystallography: photosynthesis, bacterial transport proteins, membrane complexes.
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Dr Jeremy Craven The application of solution state NMR to study the structure, dynamics and interactions of proteins and ligands.
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Dr Geoff Ford Structural and functional studies on some redox proteins.
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Prof Simon Foster Staphylococcus aureus pathogenicity and stress resistance. Bacterial cell wall structure, function and dynamics.
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Em Prof Mike Fowler Natural products of therapeutic interest, in particular those derived from plant cells.
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Dr Jim Gilmour Molecular biology of life in extreme environments, especially high salinity and low temperature environments. Bioremediation of polluted groundwater systems.
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Dr Alastair Goldman Genetic and molecular analysis of DNA double-strand break (DSB) repair in yeast. Most work is focussed on understanding how DSB repair is regulated meiosis. New efforts are being directed to mitotic DNA repair with the aim of determining how the cell ensure the DSB repair mode is least likely to cause genomic instability
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Prof Julie Gray The manipulation of plant gene expression to study the genetic control of plant signal transduction and developmental processes. Antisense gene expression to produce transgenic plants with targeted mutations is used to assign biological functions to unidentified cloned genes and also to further define the role of identified genes in planta.
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Prof Jeff Green The regulation of bacterial transcription in response to changes in oxygen availability, and to oxidative and nitrosative stress; iron-sulphur proteins as regulators; role of CRP-FNR family transcription factors in bacterial stress responses.
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Em Prof John Guest FRS Gene cloning and molecular genetic analysis of bacterial enzymes, regulatory proteins and multienzyme complexes. Control of gene expression by oxygen and metabolic activities of genetically-manipulated organisms.
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Em Prof Pauline Harrison Structure-function relationships in the iron-storage protein, ferritin. Structural and functional relationships among ferritins, di-manganese catalases and other dinuclear metal proteins.
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Dr Guillaume Hautbergue
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Dr Ewald Hettema Use of bakers' yeast, S. cerevisiae, to study membrane trafficking and membrane fission processes.
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Prof Peter Horton FRS Structure and function of photosynthetic membranes in plants: regulation of the light harvesting complexes; acclimation of photosynthesis to the changing environment; photosynthesis, abiotic stress and crop yield.
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Prof Neil Hunter FRS - Krebs Chair in Biochemistry Biogenesis, structure and function of photosynthetic membrane proteins. The enzymology of the chlorophyll and carotenoid biosynthetic pathways
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Prof Dave Kelly Molecular biology and physiology of human pathogenic bacteria, particularly Heliobacter pylori and Campylobacter jejuni. Structure, function and mechanism of a novel class of bacterial periplasmic solute transport system.
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Dr Charles McDonald Regulation of mammalian gene expression: Expression of genes for proline-rich proteins in parotid glands.
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Dr Phil Mitchell The lab’s research addresses the nature of mRNA surveillance processes in eukaryotic cells. These are quality control systems that identify and degrade incorrectly transcribed, processed or assembled mRNAs.
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Prof Anne Moir The molecular biology of spore germination in Bacillus subtilis and in the Bacillus cereus family, and the structure and assembly of coats and exosporium. The role of sigma M in the stress-resistance of vegetative cells of B. subtilis.
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Dr Arthur Moir Protein/Peptide sequencing and synthesis. DNA sequencing & synthesis. Protein-protein recognition sites on the surface of the muscle protein actin.
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Dr Lynda Partridge Human leucocyte antigens, specifically the structure/function of tetraspanins; monoclonal antibody technology. Analysis of human antibody responses using phase display.
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Prof Peter Piper Stress protein structure and function. Hsp90 molecular chaperone. Using yeast molecular genetics to study the stress protection mechanisms of ageing.
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Prof Robert Poole - West Riding Chair in Microbiology Bacterial physiology and molecular genetics, in particular respiration, nitric oxide metabolism and oxidative stress in Escherichia coli, respiratory pathways in pathogenic bacteria (especially Campylobacter and Salmonella sp.), bacterial haemoglobins, and mechanisms of transport of, and resistance to, metal ions.
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Dr John Rafferty Structural study of proteins and DNA primarily by X-ray crystallography and electron microscopy to gain 3-d insights of biological macromolecules and their assemblies. Structure and function relationships.
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Prof David Rice - Harrison Chair in Structural Biology Protein crystallography, protein crystallization; analysis of sequence homology; molecular graphics; enzyme structure and function; site-directed mutagenesis.
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Dr Sandrine Soubes Postgraduate training coordinator
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Dr Rosie Staniforth Protein mis-folding and disease : the mechanism of anyloid formation.
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Prof Peter Sudbery - Roper Chair in Genetics The molecular and cellular biology of hyphal and pseuodhyphal morphogenesis in the human fungal pathogen Candidas albicans.
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Dr Milton Wainwright Unusual aspects of microbiology. Involvement of microorganisms in ME and cancer. Isolation of microorganisms from the stratosphere. History of microbiology and public understanding of science.
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Prof Jon Waltho - Gibson Chair in Biophysics Application of multidimensional NMR methods to solving protein structures, protein folding pathways and protein molecular recognition.
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Dr Graham Warren Allele variation and adaptation in forest trees.
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Dr Don Watts Mechanism of action of bisphosphonate drugs used to treat osteoporosis and tumoural bone disease
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Prof Mike Williamson Protein structure determination by 2D and 3D NMR, and interactions with ligands. Methods for characterising protein mobility on multiple timescales.
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Prof Stuart Wilson The regulation of Gene Expression in mammals. The transport of mRNA from the nucleus to the cytoplasm. Mechanisms of RNA interference. Large scale sequencing and gene function analysis in vertebrates.
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Protein and nucleic acid biochemistry.
Protein and RNA biochemistry: expression, purification, solubility, isolation/characterisation of endogeneous complexes and reconstitution assays, analysis of interactions in vivo and in vitro, sample preparation for mass spectrometry, nuclear magnetic resonance or crystallization applications. Molecular mechanisms of eukaryotic gene expression.