Dr Cecile Perrault

Lecturer

Department of Mechanical Engineering
Sir Frederick Mappin Building
Mappin Street
Sheffield
S1 3JD
UK

Telephone: +44(0)114 2220154

Profile

Cecile Perrault received her ME and PhD in Biomedical Engineering from the University of Florida in 2005 and 2007. She then completed a postdoctoral fellowship at McGill University in Montréal, Canada in the nanobioengineering laboratory, where she developed microfluidic tools for biological purposes. In 2009, she joined the Institute of BioEngineering of Catalonia in Barcelona, Spain to study biomechanics and mechanobiology. In 2012, she joined the Department of Mechanical Engineering at the University of Sheffield as lecturer.

Cecile's research focuses on cellular mechanics and microfluidics. Her interest lies in the use of mechanical properties of cells and tissues for diagnostic purposes, with the development of microfluidic tools for cellular analysis. She is also interested in the use of mechanical stimulation for tissue engineering, more particularly bone generation in scaffolds.

Research Interests

Cellular Mechanics
Mechanobiology
Mechanotransduction
Microfluidics for Biology
Cancer Mechanics

Journal articles

Barreto S, Perrault CM, Lacroix D, Clausen CH & Fletcher DA (2013) A multi-structural single cell model of force-induced interactions of cytoskeletal components. Biomaterials, 34(26), 6119-6126.
Barreto S, Clausen CH, Perrault CM, Fletcher DA & Lacroix D (2013) A multi-structural single cell model of force-induced interactions of cytoskeletal components.. Biomaterials, 34(26), 6119-6126.
Rapier R, Huq J, Vishnubhotla R, Bulic M, Perrault CM, Metlushko V, Cho M, Tay RTS & Glover SC (2010) The extracellular matrix microtopography drives critical changes in cellular motility and Rho A activity in colon cancer cells.. Cancer cell international, 10, 24-24.
Queval A, Ghattamaneni NR, Perrault CM, Gill R, Mirzaei M, McKinney RA & Juncker D (2010) Chamber and microfluidic probe for microperfusion of organotypic brain slices.. Lab on a chip, 10, 326-34.
Perrault CM, Qasaimeh MA, Brastaviceanu T, Anderson K, Kabakibo Y & Juncker D (2010) Integrated microfluidic probe station.. The Review of scientific instruments, 81, 115107-115107.
Perrault CM, Qasaimeh MA & Juncker D (2009) The microfluidic probe: operation and use for localized surface processing.. Journal of visualized experiments : JoVE(28).
Perrault C (2009) Grant-writing offices would let scientists get on with research. Nature, 458(7236), 281-281.
Perrault CM, Qasaimeh MA & Juncker D (2009) The microfluidic probe: Operation and use for localized surface processing. Journal of Visualized Experiments(28).
Perrault CM, Juncker D & Park HE (2008) Preparation and shear modulus of polyacrylamide gels as nerve cell culture. AIP Conference Proceedings, 1027, 615-617.
Segal MS, Shah R, Afzal A, Perrault CM, Chang K, Schuler A, Beem E, Shaw LC, Li Calzi S, Harrison JK, Tran-Son-Tay R & Grant MB (2006) Nitric oxide cytoskeletal-induced alterations reverse the endothelial progenitor cell migratory defect associated with diabetes.. Diabetes, 55, 102-9.
Wolski KM, Perrault C, Tran-Son-Tay R & Cameron DF (2005) Strength measurement of the Sertoli-spermatid junctional complex.. Journal of andrology, 26, 354-9.
Glover S, Nathaniel R, Shakir L, Perrault C, Anderson RK, Tran-Son-Tay R & Benya RV (2005) Transient upregulation of GRP and its receptor critically regulate colon cancer cell motility during remodeling.. American journal of physiology. Gastrointestinal and liver physiology, 288, G1274-82.
Perrault CM, Bray EJ, Didier N, Ozaki CK & Tran-Son-Tay R (2004) Altered rheology of lymphocytes in the diabetic mouse.. Diabetologia, 47, 1722-6.
Glover S, Delaney M, Dematte C, Kornberg L, Frasco M, Tran-Son-Tay R & Benya RV (2001) Phosphorylation of focal adhesion kinase tyrosine 397 critically mediates gastrin-releasing peptide’s morphogenic properties.. Journal of Cellular Physiology, 199, 24-32.