Research projects

Examples of recent MMedSci projects

Clinical and biochemical studies:

• The role of antioxidant vitamins in oxidation of human low density lipoprotein.
• Determination of the relationship between measures of folate and antioxidant status in Buccal cells and plasma.
• Evaluation of the effects of eating breakfast on pulse wave velocity.
• Evaluation of the responsiveness of Buccal cell vitamin C concentrations to short term supplementation.
• Effects of a symbiotic preparation on the symptoms of irritable bowel syndrome.
• An investigation of the associations between folate status, genotype and cervical pathology in women with HPV infection.

Molecular nutrition studies:

• Regulation of colon cell function by the C3 short-chain fatty acid propionate.
• The regulation of apoptosis and Bcl2 family by curcumin.
• Effects of dehydration on cell viability.
• Butyrate and mismatch repair in colorectal cancer cells.
• Examination of strand breakage (ROPS assay) in Buccal cells in response to supplementation with antioxidant or folate.
• Treatment with eicosapentaenoic acid influences growth and clonogenicity.
• The impact of butyrate on specific gene expression in a colorectal cancer cell line.

Nutrition and sports science studies:

• Nutritional strategies of self-supported ultra-endurance mountain runners.
• Fluid replacement strategies of athletes - a questionnaire study
• The effects of sodium citrate on intermittent exercise performance
• Nutritional strategies for preparation and performance in ultra endurance cycling.

Community studies:

• An investigation of dietary intake and dietary knowledge in a cohort of older patients with heart failure.
• The effect of a series of "Cook and Eat" classes on dietary intake and nutritional knowledge of people with Type II diabetes.
• School lunch provision and children's food choice in three secondary schools in Sheffield. Are the new Nutritional Standards being met?
• Breakfast intake of primary schoolgirls in Jeddah, Saudi Arabia.
• An investigation of the relationship between diet and immune function in healthy elderly subjects.
• An historical analysis of food writing in women's magazines.
• Can a school-based intervention improve eating habits and body mass index of children aged 9 to 10 years living in a socially deprived area of the UK?

Energy balance studies:

• Effects of oral creatine on fat utilisation and appetite.
  
• The effect of preload volume and energy density on eating behaviour and rated appetite.
• Can alginate modulate appetite? An investigation of its effects on energy intake relative to a Slim Fast® control.
• Use of fybogel to modulate satiety.