Annual Animal Usage at the University of Sheffield for the Period 2010-2012

Please note: This information will be updated annually

The majority of research at the University is carried out using non-animal techniques, including computer modeling, tissue culture, and study of samples from humans.

However there are some cases where there is currently no complete substitute for animals. Where the use of animals remains essential, the University of Sheffield is committed, where possible, to using species of the lowest neuro-physiological sensitivity. Fish, for example, are increasingly being used instead of mammals.

Zebrafish and zebrafish embryos in particular are being used by scientists at Sheffield to learn more about human diseases and how to develop treatments for them. Zebrafish embryos develop rapidly and are transparent permitting ready observation and analysis of internal organ function, including the cardiovascular system, gut, liver and kidney. Importantly, the morphological and molecular basis of tissue and organ development is generally similar to that in humans.

For an example of how research using zebrafish is helping to save and improve lives, visit:

http://www.shef.ac.uk/research/stories/medandhealth/19.html