Mike Bradburn MSc

Senior Medical Statistician

Clinical Trials Research Unit
ScHARR
University of Sheffield
Regent Court
30 Regent Street
Sheffield
S1 4DA

Tel: +44 (0)114 22 20706
Fax: +44 (0)114 22 20870

email : m.bradburn@sheffield.ac.uk

Biography

I joined the CTRU in 2007, having previously worked as a statistician at Cancer Research UK and PAREXEL International. I specialise in providing statistical/generalist input to the CTRU portfolio of clinical trials.

Research interests

Mr primary interest is the implementation of Good Clinical Practice into NHS/academic funded clinical trials. My main areas of methodological interest are meta-analysis and survival analysis.

Teaching interests

I occasionally teach applied statistics on ScHARR modules, but my main responsibility is co-supervising two NIHR fellowships and two PhD students. They're more interesting than my teaching, see in particular Munya's fellowship:

www.shef.ac.uk/scharr/sections/dts/ctru/staff/munyadimairo

Professional activities

• Reviewer for various journals and funding bodies;
• Trial Steering Committee member for six studies, Data Monitoring & Ethics Committee member for a further two.

Current projects

I am currently involved in the following projects (all NIHR HTA-funded):

• DiPALS -- A Randomised Controlled Trial in patients with Respiratory Muscle Weakness due to Motor Neurone Disease of the NeuRx RA/4 Diaphragm Pacing Trial: http://www.sheffield.ac.uk/scharr/sections/dts/ctru/dipals
• HubBLe -- Haemorrhoidal Artery Ligation (HAL) versus Rubber Band Ligation (RBL) for haemorrhoids: http://www.controlled-trials.com/ISRCTN41394716
• MERIDIAN -- Magnetic Resonance Imaging to Enhance the Diagnosis of Fetal Developmental Brain Abnormalities in Utero: http://www.shef.ac.uk/meridian
• PLEASANT -- Preventing and Lessening Exacerbations of Asthma in School-age children Associated with a New Term: http://www.shef.ac.uk/scharr/sections/dts/ctru/pleasant/index
• REPOSE -- Relative Effectiveness of Pumps Over MDI and Structured Education: http://clinicaltrials.gov/ct2/show/NCT01616784
• SABRE -- Hypertonic Saline in Acute Bronchiolitis: A Randomised Controlled Trial and Economic Evaluation: http://www.sheffield.ac.uk/scharr/sections/dts/ctru/sabre
• TABUL -- Temporal Artery Biopsy vs ULtrasound in diagnosis of giant cell arteritis: http://clinicaltrials.gov/ct2/show/NCT00974883

Key publications

1. Bradburn M, Goodacre SW, Fitzgerald P, Coats T, Gray A, Hassan T, Humphrey J, Kendall J, Smith J, Collinson P; On behalf of the RATPAC Research Team. Interhospital variation in the RATPAC Trial (Randomised Assessment of Treatment using Panel Assay of Cardiac markers). Emergency Medicine Journal 2012; 29: 233-238
2. Goodacre SW, Bradburn M, Fitzgerald P, Cross E, Collinson P, Gray A, Hall A. The RATPAC (Randomised Assessment of Treatment using Panel Assay of Cardiac markers) trial: a randomised controlled trial of point-of-care cardiac markers in the emergency department. Health Technology Assessment 2011; 15(23): 1-108.
3. Houghton S, Saxon D, Bradburn M, Ricketts T, Hardy G. The effectiveness of routinely delivered cognitive behavioural therapy for obsessive compulsive disorder: a benchmarking study. British Journal of Clinical Psychology 2010; 49(4): 473-489
4. Harris R, Bradburn M, Deeks J, Harbord R, Altman D, Sterne J. Metan: fixed- and random-effects meta-analysis. Stata Journal 2008; 8(1): 3-28.
5. Bradburn MJ, Deeks JJ, Berlin JA, Localio AR. Much ado about nothing: a comparison of the performance of meta-analytical methods with rare events. Statistics in Medicine 2007; 26: 53-77.

View Mike's publications