The University of Sheffield
Clinical Trials Research Unit

Trials and Studies in Collaboration with CTRU

Title Chief Investigator
Organisation
Funding Body Status
3MG (Magnesium sulphate for treatment of severe acute asthma)
Ref: J06-017
Professor Steve Goodacre, MCRU Emergency & Immediate Care, ScHARR Health Technology Assessment In recruitment
Booster Trial. A randomised controlled trial and cost-effectiveness evaluation of 'booster' interventions to sustain increases in physical activity in middle-aged adults in deprived urban neighbourhoods
Ref: J07-012
Professor Liddy Goyder, Public Health, ScHARR Health Technology Assessment In recruitment
CACTUS (Computerised assisted language therapy pilot study)
Ref: JO6-025
Rebecca Palmer, Sheffield Teaching Hospitals Research for Patient Benefit In progress

DiPALS:  A Randomised Controlled Trial Evaluating NeuRx/4 Diaphragm Pacing in Patients with Respiratory Muscle Weakness Due to Motor Neurone Disease

Ref: J08-025

Dr Chris McDermott, Sheffield Institute of Translational Neuroscience NIHR Health Technology Assessment In recruitment

HubBLe: Haemorrhoidal Artery Ligation (HAL) versus Rubber Band Ligation (RBL) for haemorrhoids

Ref: J10-007

Steven Brown,
Sheffield Teaching Hospitals NHS Foundation Trust
Health Technology Assessment In set-up
Lifestyle Matters Professor Gail Mountain, ScHARR, The University of Sheffield MRC In set-up

MERIDIAN:  Magnetic Resonance Imaging to Enhance the Diagnosis of Fetal Development Brain Abnormalities In Utero

J09-07

Professor Paul Griffiths, Academic Unit of Radiology, The University of Sheffield NIHR Health Technology Assessment In recruitment
Putting Life in Years (PLINY): Evaluation of the Comparative Effectiveness and Cost Effectiveness of an Intervention to Promote Mental Wellbeing in Community Living Older People

Ref: J09-015

Professor Gail Mountain, ScHARR, The University of Sheffield NIHR Public Health Research Programme In set-up
The randomised evaluation of the effectiveness and acceptability of computerised therapy (REEACT) trial.
Ref: J06-021
Dr Simon Gilbody, University of York Health Technology Assessment In recruitment
REPOSE: The Relative Effectiveness of Pumps over MDI and Structured Education for Type-1 Diabetes Professor Simon Heller, School of Medicine, The University of Sheffield Health Technology Assessment In recruitment
SABRE: Hypertonic Saline in Acute Bronchiolitis: Randomised Controlled Trial and Economic Evaluation
Ref: JO8-032
Professor Mark Everard, Paediatric Respiratory Medicine Department, Sheffield Children's NHS Foundation Trust Health Technology Assessment In recruitment
South Yorkshire Cohort - Obesity Reduction in South Yorkshire. Part of CLAHRC.
Ref: J08-012
Dr Paul Bissell, ScHARR National Institute for Health Research In recruitment
TABUL (The role of ultrasound compared to biopsy of tempural arteries in the diagnosis and treatment of giant cell arteritis Dr Raashid Luqmani, University of Oxford Health Technology Assessment In recruitment



Trials and Studies supported by CTRU


Title Chief Investigator
Organisation
Funding Body Services
The CoPE (Corn Plaster Evaluation) Trial. The long term effectiveness of 40% salicylic acid plasters on corns.
Ref: J07-022
Brenda King/Professor Wesley Vernon, Sheffield Primary Care Trust Research for Patient Benefit Data Management
Statistics
Trials advice
Randomisation
The CoughAssist minimisation trial (evaluation of use of mechanical in-exsufflator in patients with motor neurone disease) Professor Pamela Shaw,School of Medicine Health Technology Assessment Randomisation