The Florey Institute for Host-Pathogen Interactions

Understanding how the human body reacts to pathogens and how treatments can be developed to take this into consideration.


Establishment of the Florey Institute in Sheffield will create a leading international hub for new approaches to the understanding and treatment of infectious diseases and provide a platform for their clinical translation. The Institute will focus on understanding the interaction between infective bacteria (pathogen) and our own immune systems (host). In the past the predominant focus has been on how the pathogen causes disease, with little attention to how the human body can prevent disease and why this in some cases fails. Comparatively little is understood about how most healthy people avoid serious disease following infection or the nature of the core components that ensure a successful host response to infections.

We will develop a holistic approach that addresses correction of all aspects of the disease state, rather than the more simplistic and increasingly redundant approach of simply killing the bacteria. It will provide an innovative and unique approach through its distinct scientific focus, the application of novel interdisciplinary collaborations and its collaborative translational approach involving industry partners.


Get in touch with our Florey Institute team to find out more.

Professor Simon Foster, Florey Institute Coordinator

Telephone: 0114 222 2160

Department of Molecular Biology and Biotechnology
University of Sheffield
Firth Court, Western Bank
Sheffield S10 2TN

Dr Chrissy Sammut, Florey Institute Project Manager

Telephone: 0114 222 1054

Research & Innovation Services
New Spring House
231 Glossop Road
S10 2GW

Visit the The Florey Institute website.