APS 268 Genomics, Proteomics and Metabolomics

Level 2
Semester 1B
Credits 10
Pre/Co Requisites APS 125
BMS 157
Recommended Requisites -
Teaching Staff Professor Andrew Fleming, Dr Gareth Fraser, Dr Janice Lake
Co-ordinator Professor Andrew Fleming


This module will:

1. Provide an introduction to genomic, proteomic and metabolomic technologies.
2. Outline the experimental basis of the techniques e.g. microarrays, protein gel electrophoresis, metabolite profiling etc.
3. Evaluate, through the use of case studies, how these technologies provide a better understanding of the complexities of whole organisms and biological systems.


The new 'omics' technologies allow the components of a living organism to be analysed in their entirety and provide new insights into the complexities of organism function. This 'whole-picture' approach distinguishes the 'omics' from other, more reductionist methods. Genomics and transcriptomics tell us about the structure and expression of the genome, proteomics provides information about the proteins present within cells, whilst metabolomics seeks to identify and quantify the diversity of metabolites and metabolic networks within an organism. In this course the student will learn how the 'omics' technologies work, and about aspects of experimental design, analysis and interpretation (bioinformatics). A series of case studies will be used to illustrate how these technologies engender a better understanding of complex biological systems and processes.

Delivery Method: Lectures, seminars, project work

Student Contact Hours: 18

Assessment Method: 1 1/2 hour examination consisting of short answer questions and one essay type question.

For more information on APS268, please go to MOLE.

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