Zebrafish help unlock mystery of motor neurone disease
The breakthrough will help to accelerate pioneering research and experimental drug trials to tackle the degenerative disease.
Until now, research to better understand how the disease occurs and the trial of experimental drugs has been conducted on fruit flies or mice models. This has had limited success due to the difference between the human brain and the fruit fly brain, and the time and cost implications of using mice models.
The four year project, which was led by Bateson member Dr Tennore Ramesh in collaboration with leading researchers from SITraN including Professor Dame Pamela Shaw, Vice-President and Head of the Faculty of Medicine, Dentisry and Health at the University of Sheffield, is published in the journal Acta Neuropathologica Communications. The study was funded by the MND Association.