Dr Natalia Bulgakova

Department of Biomedical Science

Lecturer

Natalia Bulgakova
n.bulgakova@sheffield.ac.uk
+44 114 222 3649

Full contact details

Dr Natalia Bulgakova
Department of Biomedical Science
D43e
Firth Court
Western Bank
Sheffield
S10 2TN
Profile
  • 2015-present: Lecturer, Department of Biomedical Sciences, University of Sheffield, UK
  • 2009-2015: Research associate, Gurdon Institute, University of Cambridge, UK
  • 2007-2009: Research associate, Max-Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
  • 2004-2007: 2004-2007: PhD, Institut für Genetik, Heinrich-Heine Universität Düsseldorf, Germany
Research interests

The mechanism that attaches neighbouring cells in our body to each other is known as cell-cell adhesion. Recent work has demonstrated that cell-cell adhesion is also important for communication between the neighbouring cells to decide when to divide, migrate or die.

Our lab is interested to understand how cell-cell adhesion contributes to normal development of a whole organism. We focus on E-cadherin, a transmembrane protein that provides cell-cell adhesion between the epithelial cells.

Using a combination of genetic assays, biochemistry and quantitative imaging techniques in Drosophila model system we study how E-cadherin functions in various developmental processes, for example cell neighbour exchange and tissue growth, and how it is regulated during development. In future, we aim to apply this knowledge about normal function of E-cadherin to treatment of medical conditions arising from defects in E-cadherin function such as epithelia-derived tumours.

Publications

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Journal articles

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Journal articles

Conference proceedings papers

Teaching activities

Undergraduate and postgraduate taught modules:

  • BMS109 Lab Skills & Skills Sessions
  • BMS110 Research Topics in Biomedicine
  • BMS334 Epigenetics
Opportunities

We advertise PhD opportunities (Funded or Self-Funded) on FindAPhD.com

For further information and details of other projects on offer, please see the department PhD Opportunities page.