Mr Tom Sheard

School of Biosciences

Research Associate

Tom Sheard
T.Sheard@sheffield.ac.uk
N/A

Full contact details

Mr Tom Sheard
School of Biosciences
Firth Court
Western Bank
Sheffield
S10 2TN
Profile
  • 2021-present – Postdoctoral research associate, Dept. of Molecular Biology and Biotechnology, University of Sheffield, UK
Qualifications
  • 2016-2021 – PhD, Faculty of Biological Sciences, University of Leeds, UK
  • 2015-2016 – MPhil, Faculty of Biology, Medicine and Health, University of Manchester, UK
Research interests
Super-resolution microscopy imaging techniques allow scientists to see nanoscale structures. These techniques often require specialist equipment and knowledge, rendering them inaccessible to a significant number of scientists in the field.
 
In my post-doctoral research position I will develop accessible imaging techniques, making use of the novel super-resolution technique called expansion microscopy (ExM), which uses expanding hydrogels to physically inflate a sample to increase the resolution of imaging.
 
I will innovate the ExM methodology, investigating new gel chemistries, fluorescent probes, and understanding the even-ness (isotropy) of expansion with calibration structures.
 
I am interested in implementing ExM in novel applications which will benefit from improved resolution to see biological targets such as proteins, lipids and genetic material.