Dr Henry Roehl: Publications
Clinical pathologies of bone fracture modelled in zebrafish. Disease Models & Mechanisms, 12(9), dmm037630-dmm037630.
Damage-induced reactive oxygen species enable zebrafish tail regeneration by repositioning of Hedgehog expressing cells. Nature Communications, 9(1). View this article in WRRO
Linking wound response and inflammation to regeneration in the zebrafish larval fin.. The International Journal of Developmental Biology, 62(6-8), 473-477. View this article in WRRO
Expression of osterix Is Regulated by FGF and Wnt/β-Catenin Signalling during Osteoblast Differentiation. PLOS ONE, 10(12). View this article in WRRO
A bi-modal function of Wnt signalling directs an FGF activity gradient to spatially regulate neuronal differentiation in the midbrain.. Development, 141(1), 63-72.
Loss of function of parathyroid hormone receptor 1 induces Notch-dependent aortic defects during zebrafish vascular development.. Arterioscler Thromb Vasc Biol, 33(6), 1257-1263.
Delivery systems for small molecule antiprion drug candidates. PRION, 6, 99-99. View this article in WRRO
HSPG-deficient zebrafish uncovers dental aspect of multiple osteochondromas. PLoS ONE, 7(1). View this article in WRRO
Differentiated skeletal cells contribute to blastema formation during zebrafish fin regeneration. Development, 138(18), 3897-3905.
Regulation of Zebrafish Hatching by Tetraspanin cd63, 6. View this article in WRRO
Ret signalling integrates a craniofacial muscle module during development. Development, 138(10), 2015-2024.
Regulation of zebrafish hatching by tetraspanin cd63.. PLoS One, 6(5), e19683. View this article in WRRO
Discovery of 6-substituted indole-3-glyoxylamides as lead antiprion agents with enhanced cell line activity, improved microsomal stability and low toxicity.. Eur J Med Chem, 46(9), 4125-4132.
Hedgehog signalling is required for perichondral osteoblast differentiation in zebrafish.. Mech Dev, 128(1-2), 141-152.
Shop talk: Sugars, bones, and a disease called multiple hereditary exostoses.. Dev Dyn, 239(6), 1901-1904.
Regulation of neural crest cell fate by the retinoic acid and Pparg signalling pathways.. Development, 137(3), 389-394.
Ret tyrosine kinase signalling is required for the development of a functionally related set of zebrafish head muscles. MECHANISMS OF DEVELOPMENT, 126, S161-S161.
Tracking gene expression during zebrafish osteoblast differentiation. Developmental Dynamics, 238(3), spcone-spcone.
Zebrafish Model for Studies on Bone Defects in Multiple Osteochondromas. LABORATORY INVESTIGATION, 89, 25A-25A.
Zebrafish Model for Studies on Bone Defects in Multiple Osteochondromas. MODERN PATHOLOGY, 22, 25A-25A.
Tracking gene expression during zebrafish osteoblast differentiation.. Dev Dyn, 238(2), 459-466.
montalcino, A zebrafish model for variegate porphyria. Experimental Hematology, 36(9), 1132-1142.
The multidomain protein Brpf1 binds histones and is required for Hox gene expression and segmental identity. DEVELOPMENT, 135(11), 1935-1946.
Regulation of zebrafish skeletogenesis by ext2/dackel and papst1/pinscher.. PLoS Genet, 4(7), e1000136. View this article in WRRO
Conserved functions of Ikaros in vertebrate lymphocyte development: Genetic evidence for distinct larval and adult phases of T cell development and two lineages of B cells in zebrafish. Journal of Immunology, 177(4), 2463-2476.
Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis. Nature, 436(7053), 1035-1039.
beamter/deltaC and the role of Notch ligands in the zebrafish somite segmentation, hindbrain neurogenesis and hypochord differentiation. Developmental Biology, 286(2), 391-404.
Integrinα5 and delta/notch signaling have complementary spatiotemporal requirements during zebrafish somitogenesis. Developmental Cell, 8(4), 575-586.
The chianti zebrafish mutant provides a model for erythroid-specific disruption of transferrin receptor 1. Development, 131(24), 6225-6235.
Mutations in cadherin 23 affect tip links in zebrafish sensory hair cells, 428, 955-959.
The deafness gene dfna5 is crucial for ugdh expression and HA production in the developing ear in zebrafish. Development, 131(4), 943-951.
Axon sorting in the optic tract requires HSPG synthesis by ext2 (dackel) and extl3 (boxer). Neuron, 44(6), 947-960.
Fgf3 signaling from the ventral diencephalon is required for early specification and subsequent survival of the zebrafish adenohypophysis. Development, 131(15), 3681-3692.
Slb/Wnt11 controls hypoblast cell migration and morphogenesis at the onset of zebrafish gastrulation. Development, 130(22), 5375-5384.
A zebrafish homologue of the chemokine receptor Cxcr4 is a germ-cell guidance receptor. Nature, 421(6920), 279-282.
Analysis of a zebrafish VEGF receptor mutant reveals specific disruption of angiogenesis. Current Biology, 12(16), 1405-1412.
Zebrafish pea3 and erm are general targets of FGF8 signaling. Current Biology, 11(7), 503-507.
A radiation hybrid map of the zebrafish genome. Nature Genetics, 23(1), 86-89.
The origin and evolution of animal appendages. Proceedings of the National Academy of Sciences of the United States of America, 94(10), 5162-5166.
Roles of the RAM and ANK domains in signaling by the C.elegans GLP-1 receptor. EMBO Journal, 15(24), 7002-7012.
Control of cell fate in C. elegans by a GLP-1 peptide consisting primarily of ankyrin repeats. Nature, 364(6438), 632-635.
Conference proceedings papers