Biomedical Science

MSc Biomedical Science

Biomedical science is about deepening our understanding of the human body in health and disease, helping to develop treatments that can save and improve lives. This research-led masters course is taught by experts in key areas of modern biology, including cell biology, developmental biology, neuroscience and stem cells.

Over the last twenty years, research in biomedical science has revolutionised our understanding of biological systems. Important discoveries continue to be made here at the University of Sheffield, where researchers are working with partner institutions to apply results from the lab to regenerative treatments for diseases like Parkinson's. Other researchers have transplanted stem cells to restore the hearing in gerbils, and offered hope in the search for treatments for motor neuron disease.

Students have access to outstanding, purpose-built facilities such as our Drosophila and Zebrafish Facilities, where studies of model organisms are helping researchers to identify human disease pathways. We also host state-of-the-art light microscopy and electron microscopy facilities, drug and RNAi screening facilities, and proteomics and single cell omics facilities. This means we can provide training in the analysis of biological systems from the molecular and cellular level to tissues and whole organisms.

Find out more about Biomedical Science research at the University Sheffield

Applying

To apply for this course, complete the University of Sheffield's postgraduate online application form.

Online application form

You can find more information about the application process on the University's postgraduate webpages.

How to apply: applying essentials

Contact

Course Director: Professor Steve Winder

If you have any questions about this course, contact our admissions office: bmspgadmissions@sheffield.ac.uk | +44 (0)114 222 2319

You can also visit us throughout the year:
Postgraduate open days, visit afternoons and online chats

Pathway programme for international students
Don't meet our entry requirements? Pre-Masters in Science and Engineering

About the course

I found the cancer biology theoretical course and the cell biology practical course to be challenging yet highly useful in the long run.

Anjana Venkataramanan, MSc Biomedical Science  READ MORE

This 12-month course brings together expertise from across Biomedical Science to offer a wide range of practical and lecture modules in cell biology, developmental biology, neuroscience and stem cells. This gives you the flexibility to cover a range of bioscience topics, or specialise, depending on your career goals. Possible topics include developmental genetics, epithelial physiology, tissue engineering and cancer biology – a full list of current modules is given below. You'll also get training in the skills every professional scientist needs, such as research ethics and literature analysis.

The biggest part of your degree will be your research project. You'll be based in one of our world-class research groups, working alongside professional scientists and under the supervision of one of our academic staff. They'll train you to use the specialist equipment that you'll need to complete your project, and provide support to help you design your experiments, analyse your results and present your findings.

Research facilities in Biomedical Science

Throughout your degree, you'll be taught through lectures, practical sessions and lab placements. The course is designed to build on your undergraduate studies or related work experience so that you can gain the specialist knowledge and practical skills required for a great career in biomedical science, including further study at PhD level.

Discover our research – from cells to organisms in health and disease

Read more about this course on the University of Sheffield's webpages for postgraduate students:

MSc Biomedical Science

Entry requirements

For this course, we usually ask for a good upper second class (2:1) honours degree, or equivalent, in a biomedical or related subject such as biochemistry, genetics, zoology, cell biology or biochemistry. Applicants with relevant work experience and good academic potential are also encouraged to apply.

We can also accept equivalent qualifications from other countries. You can find out which qualifications we accept from your country on the University's webpages for international students.

Prospective international students: Your country

International pathway programmes

If you are an international student who does not meet our entry requirements, the University of Sheffield International College offers a Pre-Masters in Science and Engineering programme. This programme is designed to develop your academic level in your chosen subject, introduce you to the study skills that will be vital to success and help with language if you need it.

Upon successful completion, you can progress to this degree at the University of Sheffield.

Pre-Masters in Science and Engineering

English Language Requirements

If you have not already studied in a country where English is the majority language, it is likely that you will need to have an English language qualification.

  • International English Language Testing Service (IELTS): Overall grade of 6.5 with 6.0 in each component

You can find out whether you need to have an English language qualification, and which other English language qualifications we accept, on the University's webpages for international students.

English language requirements

The English Language Teaching Centre offers English language courses for students who are preparing to study at the University of Sheffield.

English Language Teaching Centre

Fees and funding

Up-to-date fees and funding opportunities can be found on the University of Sheffield's webpages for postgraduate students. These may include scholarships for home and international students and a 10% discount for University of Sheffield graduates.

Tuition fees

Funding your postgraduate course

Current modules

Core modules – students take all four:

Retrieval and
Evaluation of Research Information

Before starting on the laboratory component of their research, project students must undertake an in depth survey of the literature relevant to the project and prepare a research proposal. Students will be required to carry out an exhaustive search of material relevant to their project using the resources of the University, including the web. This will involve primarily private study by the student under the direction of the project supervisor who will meet with the student at regular intervals to ensure satisfactory progress.

Laboratory Research Project

The unit aims to provide students with experience of laboratory research and develop their practical and organisational skills required for a career in science. Students undertake a project related to their area of specialization which reflects the research activities in the Department. Projects will run in the laboratories of the research groups and although students will have contact with various staff, each student will have an identified member of staff as their project supervisor. Students will gain experience of experimental design and execution and in the collation, interpretation and presentation of data. Assessment of the project will be based on; a written report, laboratory performance, delivery and defence of an oral presentation, a poster presentation and an oral examination.

Critical Analysis of Current Science

This unit is designed to develop the student’s ability to read and understand the scientific literature relating to their own research area and also enable them to integrate their own work into the wider scientific field. The unit consists of three components; a tutorial/seminar programme of up to 16 tutorial sessions designed to develop student skills in reading, understanding and criticising scientific literature; attendance at departmentally organised review lectures covering broad areas of science delivered by internationally recognised scientists; participation in all support sessions provided by the research groups in support of their research programme. Each component would be assessed separately with written reports, some undertaken under formal examination conditions.

Ethics and Public Awareness of Science

This unit introduces an outline of the legislative limitations and ethical influences on biomedical science. It will address how these are influenced by public attitudes and explore how these, in turn, are influenced by the scientific community. The unit will contain a factual and objective core, however students will be encouraged to explore, develop and express their own beliefs and value systems.

Practical modules – students choose two:

Practical Developmental Genetics

The practical unit aims to provide students with experience of research techniques in developmental biology. Students will perform experiments designed to reveal molecular and cellular principles underpinning developmental mechanisms. Emphasis will be placed on exploiting classical genetic and molecular resources available in model organisms such as zebrafish, Drosophila melanogaster, and chick for studying gene function in development. Students will gain experience of performing experimental work, data collection and interpretation of results.

Practical Cell Biology

The practical unit will provide students with experience of practical cell biology.  Students will be given the opportunity to establish and optimise ELISA-based assays for the endocytic pathway and the role of the cytoskeleton will be investigated in aspects of the endocytic process using inhibitors and fluorescence microscopy of fixed cells. Particular emphasis will be placed on the development, execution and interpretation of experimental protocols as is standard practice in a research laboratory.

Neuroscience Techniques

This module aims to introduce students to a range of laboratory techniques. Students are given the principles of tissue culture, basic sterile technique and the aseptic preparation of buffers and media. Reference is made to the special requirements of neural cell culture. They will also gain experience of cell culture together with training in aspects of cryostat and paraffin section preparation. Class practical sessions utilise student-prepared sections and cells to perform standard histochemical and immunohistochemical procedures, and different methods for tract tracing within nervous system tissue. Images derived from the practicals are analysed using computer based image processing techniques.

Practical Physiology and Pharmacology

Description of this module to follow shortly.

Numbers of participants may be restricted on practical modules in order to maintain an effective laboratory learning experience.

Lecture modules – students choose two:

Sensory Neuroscience

This module covers the adult function and functional development of auditory, visual and whisker systems, including sensory transduction, signal selectivity and information coding. It will focus primarily on the periphery but will include representation of information in central pathways, with attention to animal models including mammals, fish and flies. The aims will be to show how physiological and developmental mechanisms combine to create the exquisite structural and functional tuning of sensory systems to the external world and how complex sensory information is encoded in the nervous system. Special attention will be given to comparative analysis of auditory and visual systems.

Modelling Human Disease

This unit aims to provide students with an understanding of the way that post-genomic developmental biology is impacting on our ability to understand, and treat, human disease. Students will be introduced to some of the major experimental systems and approaches that are pertinent to disease modelling. These include genetically-tractable animal model systems, in vitro cellular systems, including stem cells, and bioinformatics. The principles involved in establishing how these systems can be exploited to develop new strategies for regeneration, and the prevention of degeneration, will be explored. Lectures will be interspersed with critical evaluations of primary research papers, so that students gain experience of analysing experimental work, data presentation and interpretation of results.

Developmental Neurobiology

This course examines the mechanisms that underlie development of the nervous system during embryogenesis. Examples will be described from a variety of model organisms to introduce key steps in the establishment of the CNS and PNS, steps that include neural induction, neural patterning, early segregation of CNS and PNS, the establishment and refinement of connectivity in the nervous system. Recent research from teachers of this course, and from both the classical and current literature is used to analyse and evaluate theories and mechanisms of establishment of the functional nervous system.

Cancer Biology

The unit will provide a description and explanation of the characteristics of tumour cells and their relationship to the tissues of origin; genetic and environmental factors in the origins of tumours; cell culture models and animal models; carcinogenesis as a multi-step process, including the concept of stem cells, (cell proliferation and cell differentiation, metastasis and tumour-host interactions; oncogenes, tumour suppressor genes and oncogenic viruses; the relationships between tumour biology and developmental biology; tumour immunology; examples of particular tumours will be used to illustrate the foregoing topics.

Epithelial Physiology in Health and Disease

The aim of this course is to provide an understanding of the strategies used by epithelia to effect transport of ions and water, and to explore the pathophysiological states associated with a number of inherited diseases, such as cystic fibrosis. Teaching will consist of conventional lectures together with problem solving exercises. The module initially considers the general properties of epithelia, before focusing on the molecular basis of epithelial transport in health and disease. The emphasis throughout will be to appreciate how experimental research informs our understanding of these issues, reflecting the University’s mission statement to lead teaching by current research.

Stem Cell Biology

This lecture course will provide a thorough grounding in the biology of stem cells and regenerative medicine, with special reference to the molecular and genetic control of cell fate specification and differentiation. Students will also be encouraged to consider the clinical use of stem cells and their derivatives as well as the ethical issues that these raise. As this is a rapidly developing field, strong emphasis will be placed on understanding the current controversies in the literature.

Tissue Engineering in Biomedical Science

The aim of this unit is to equip students with knowledge and understanding of the fundamental principles of tissue engineering. It will also develop their ability to evaluate current and potential tissue engineering applications, and to make suggestions for novel approaches.

Physiology of Ion Channels and Disease

The aim of this module is to provide an understanding of ion channel physiology and pathophysiology in a variety of electrically excitable cells such as muscle and the nervous system, and to give an appreciation of the methodologies used in modern ion channel research.

Membrane Receptors

The aim of this module is to provide an understanding of membrane receptors for extracellular signalling molecules, including their molecular structure and transduction mechanisms, their roles in cell physiology, and their exploitation as targets for therapeutic drugs.

The modules listed above are examples from the current academic year. There may be some changes before you start your course.

The content of our courses is reviewed annually to make sure it's up-to-date and relevant. Individual modules are occasionally updated or withdrawn. This is in response to discoveries through our world-leading research, funding changes, professional accreditation requirements, student or employer feedback, outcomes of reviews, and variations in staff or student numbers.

Some optional practical and lecture modules share the curriculum with final year undergraduates.