Dr Raman Vaidyanathan

Dr Raman Vaidyanathan

Senior Lecturer in Chemical Engineering
Course Director MSc  (Eng) Biological and Bioprocess Engineering
Course Director MSc (Eng) Biochemical Engineering with Industrial Management


Profile

I joined the Department as a lecturer in 2007. I'm a chemical graduate with a Masters degree in Biotechnology (both from India) and completed my PhD in 2001 from the University of Strathclyde in Glasgow, where I investigated the application of near infrared spectroscopy to monitor industrially relevant bioprocesses involving filamentous microorganisms. This was work done in collaboration with Eli Lilly.  I have over five years of pre-doctoral industrial experience applying biotechnological solutions to environmental engineering problems.

Before joining Sheffield I was a research associate at the University of Manchester, where I investigated a) the application of secondary ion mass spectrometry with buckminsterfullerene (C60) cluster ions as primary ion sources to characterize biological surfaces, and b) laser desorption ionization mass spectrometry for metabolomic applications. I also spent my post-doctoral years investigating the application of soft ionization mass spectrometry to characterize biological systems, at Aberystwyth in Wales.


Research

  • Bio-energy
  • Metabolomics
  • Mass spectrometry imaging
  • Microbial biotechnology

Teaching

  • CPE403/6030 - Environment: Gaseous Emissions
  • CPE401 - Research Project (MEng)
  • CPE6009 – Bio-energy
  • CPE6016 – Bioanalytical Techniques (MSc BBE)

Publications

Journal articles
Conference proceeding papers
  • Vaidyanathan S, Salim M, Hurley C & Pugh J (2013) Vapour-mediated ion activation for enhanced SIMS imaging. SURFACE AND INTERFACE ANALYSIS, Vol. 45(1) (pp 290-293)  
  • Vaidyanathan S (2013) Cellular metabolic profiling using ToF-SIMS. SURFACE AND INTERFACE ANALYSIS, Vol. 45(1) (pp 255-259)  
  • Vaidyanathan S & Longworth J (2009) BIOT 402-Seeking the message in the medium: Metabolic footprints of microalgal cultivations for bioenergy. ABSTR PAP AM CHEM S, Vol. 238  
  • Vaidyanathan S (2009) ANYL 380-Matrix effects in biomolecular imaging using ToF-SIMS. ABSTR PAP AM CHEM S, Vol. 238  
  • Fletcher JS, Henderson A, Biddulph GX, Vaidyanathan S, Lockyer NP & Vickerman JC (2008) Uncovering new challenges in bio-analysis with ToF-SIMS. APPLIED SURFACE SCIENCE, Vol. 255(4) (pp 1264-1270)  
  • Vaidyanathan S, Fletcher JS, Lockyer NP & Vickerman JC (2008) TOF-SIMS investigation of Streptomyces coelicolor, a mycelial bacterium. APPLIED SURFACE SCIENCE, Vol. 255(4) (pp 922-925)  
  • Vaidyanathan S, Fletcher JS, Henderson A, Lockyer NP & Vickerman JC (2008) Exploratory analysis of TOF-SIMS data from biological surfaces. APPL SURF SCI, Vol. 255(4) (pp 1599-1602)  
  • Vaidyanathan S, Lopez-Diez C & Goodacre R (2007) Proteome and metabolome analyses for rapid authentication of food.. Rapid Methods Europe 2005 (pp 29-48). Noordwijk aan Zee, the Netherlands, 24 May 2005 - 25 May 2005.  
  • Vaidyanathan S, Jones D, Jenkins T, Kell DB & Goodacre R (2005) Metabolomic investigations using laser desorption ionisation mass spectrometry on porous silicon. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 229 (pp U245-U245)  
  • Vaidyanathan S, Kell DB & Goodacre R (2005) Electrospray-ionization mass spectrometry of protein mixtures: Influence of instrumental settings and proteomic implications.. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 229 (pp U185-U185)  
  • Vaidyanathan S & Goodacre R (2003) Metabolite and protein profiling of whole cells using soft-ionization mass spectrometry for rapid microbial characterization.. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 225 (pp U199-U199)  
  • Vaidyanathan S, Kell DB & Goodacre R (2002) Rapid, high-throughput microbial characterization by metabolite and protein profiling of whole cells using soft-ionization mass spectrometry.. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 224 (pp U199-U199)  
  • Vaidyanathan S, Macaloney G & McNeil B (2000) Measurement of mycelial biomass in a submerged bioprocess using near infrared spectroscopy.. NIRS-’99 - Proceedings of the 9th International conference on Near-infrared spectroscopy (pp 429-433). Chichester, UK  
Chapters
  • Vaidyanathan S & Goodacre R (2005) Understanding the behaviour of pathogenic cells: proteome and metabolome analyses, Understanding Pathogen Behaviour(pp. 3-52). Elsevier  
  • Vaidyanathan S & Goodacre R (2005) Understanding the behaviour of pathogenic cells: proteome and metabolome analyses. In Griffiths M (Ed.), Understanding Pathogen Behaviour (pp. 3-52). CRC Press  
  • Vaidyanathan S & Goodacre R (2003) Proteome and metabolome analyses for food authentication, Food Authenticity and Traceability (pp. 71-100). Elsevier  
  • Vaidyanathan S & Goodacre R (2003) Metabolome and Proteome Profiling for Microbial Characterization, Metabolic Profiling: Its Role in Biomarker Discovery and Gene Function Analysis (pp. 9-38). Springer US  
  • Vaidyanathan S & Goodacre R (2003) Metabolome and proteome profiling for microbial characterization: Mass spectrometric applications. In Harrigan GG & Goodacre R (Ed.), Metabolic Profiling (pp. 9-38). Springer  
  • Vaidyanathan S & Goodacre R (2003) Proteome and metabolome analyses for food authentication In Lees M (Ed.), Food authenticity and traceability [electronic resource] (pp. 71-100). Woodhead Publishing  
Books
  • Vaidyanathan S, Harrigan GG & Goodacre R (2005) Metabolome Analyses:. Springer.