PhD studentships in CHO Cell Engineering and Synthetic Biology

Have you got what it takes to join a Department that is number 1 for research environment?  The Department has five bioindustry-linked PhD studentships are available in Professor David James laboratory at The University of Sheffield.

1. Design of synthetic genetic components for controlled expression of recombinant genes in mammalian cells. In collaboration with Merck, Corsier-sur-Vevey, Switzerland. 
2. Cell and process engineering for transient expression of recombinant proteins in CHO cells. BBSRC/IBiolC (http://www.ibioic-ctp.com) in collaboration with Absolute Antibody Ltd., Redcar, U.K. 
3. Synthetic biology platform development for manufacture of next generation biologics. BBSRC, in collaboration with MedImmune, Cambridge, U.K. 
4. Impact of microvesicles on biologics production. In collaboration with Lonza Biologics, Slough, U.K. 
5. Cell derived impurities in culture media: Evaluating the risk to product integrity and downstream purification. EPSRC/UCL (http://www.ucl.ac.uk/biochemeng/research/epsrc-cdt), in collaboration with MedImmune, Cambridge, U.K.

Students will join an established, active research laboratory working in partnership with bioindustry and will receive an advanced training in technologies relevant to biopharmaceutical manufacturing. Students have access to expertise and world-class research facilities at the University of Sheffield and partner companies.

Applications are invited from UK or EU nationals who have, or expect to be awarded an upper second or first class honours degree (or the equivalent) in molecular bioscience, (bio)chemical engineering or a related discipline. Candidates with an appropriate Master’s degree are also eligible to apply.

Successful candidates will receive an enhanced living allowance of £18,553 per annum for 3.5 years, which includes £4,000 per annum from the industrial partner. Funding for university tuition fees and experimental consumables is provided by research studentship sponsors.

The formal online application process can be accessed via this form.

Informal enquiries can be directed to Professor David James d.c.james@sheffield.ac.uk