Understanding microbial-surface attachments

Biofilm formation is a significant factor in processes such as biofouling, medical implant failure and infection aetiology. Current work is focussed on resolving the conformation of microbial macromolecules such as lipopolysaccharide on mineral surfaces by using surface spectroscopy and atomic force microscopic techniques. This experimental work is being developed in parallel to computational simulations so the dominant molecular interactions may be quantified. The aim is to establish the conformational properties of constituent macromolecules of outer cell-wall origin during binding to mineral surfaces.

Research staff: Dr Rachel Walton