EPSRC Grant for Dr Seb Spain

Dr Seb Spain has recently been awarded funding from the Engineering and Physical Sciences Research Council (ESPRC) for a project entitled "Oxidation-sensitive nanomaterials for treatment of immune diseases". The project aims to develop new materials that respond to the biochemical environment found at sites of inflammation for the treatment of inflammatory diseases such as rheumatoid arthritis and multiple sclerosis.

Graphic of Dr Seb Spain's researchOf the project Dr Spain said "We tend to consider our immune system as our protector, fighting off bacteria and viruses. To do this, the it produces a large amount of toxic and damaging chemicals to destroy the infection. However, when the immune system goes wrong these same chemicals can cause chronic diseases such as rheumatoid arthritis and multiple sclerosis. There is even a large immune component in cancers and trauma."

"Our aim here is to develop a range of materials that respond to these chemicals. That response might be a change in size, shape or solubility, and we will use that change to release a drug to detect or treat sites of inflammation."

This work is supported by EPSRC Grant EP/P027989/1.