Dr Sarah Staniland
Department of Chemistry
Reader in Bionanoscience
+44 114 222 9539
Full contact details
Department of Chemistry
13 Brook Hill
Dr. Sarah Staniland obtained her MChem degree at the University of Edinburgh in 2001. This was followed by a PhD in magnetic materials (dept. Chemistry, Edinburgh) which she completed in 2005. After this she won an independent EPSRC life science interface fellowship (2005-2008) at the University of Edinburgh where she initiated the research she is currently active in.
This helped her transition from the chemical material sciences to interdisciplinary work at the interface with biology. She then moved to the University of Leeds to take up a Lectureship in Bionanoscience in the School of Physics and Astronomy where she was promoted to Associate Professor (2008-2013). She moved to Sheffield as a Senior Lecturer in Bionanoscience in 2013, and was promoted to Reader in 2017.
- RSC Harrison-Meldola Prize (2016)
- Research interests
Our group seeks to synthesis novel precise bio/mineral nanomaterial architectures for nanotechnological and biomedical applications. Inspired by nature, we are using functional proteins such as biomineralisation proteins and lipid membrane to create hybrid functional nanomaterial and arrays. The main interest is the formation of membrane surrounded magnetite nanoparticles. These are biomineralised in nature within magnetic bacteria and are termed magnetosomes. Currently we are working on a number of projects such as:
- using genetic engineering and transition metal solution chemistry to alter and enhance the magnetosome particles in vivo;
- using the magnetic bacterial Mms proteins to control the synthesis of enhanced and functional magnetite nanoparticles in vitro;
- performing these biomimetic formations on surfaces in organised and functional arrays;
- using these and lipid membranes to surround the particles and attach them to surfaces;
- Use physical and biological probes to analysis how these biomineralisation protein actually control this process so precisely.
The research is intrinsically multi-disciplinary, spanning: magnetic characterisation, chemical synthesis, nanotechnological engineering, proteomics, genetics, environmental, and micro-biology.
- Green Nanomaterials. Bristol, UK: IOP Publishing.
- Green Nanomaterials: From bioinspired synthesis to sustainable manufacturing of inorganic nanomaterials. IOP Publishing.
- Systematic Screening and Deep Analysis of CoPt Binding Peptides Leads to Enhanced CoPt Nanoparticles Using Designed Peptides. Bioconjugate Chemistry, 31(8), 1981-1994.
- Investigating the ferric ion binding site of magnetite biomineralisation protein Mms6. PLOS ONE, 15(2). View this article in WRRO
- Rational Design and Self-Assembly of Coiled-Coil Linked SasG Protein Fibrils. ACS Synthetic Biology, 9(7), 1599-1607.
- Macrofluidic coaxial flow platforms to produce tunable magnetite nanoparticles : a study of the effect of reaction conditions and biomineralisation protein Mms6. Nanomaterials, 9(12). View this article in WRRO
- Artificial coiled coil biomineralisation protein for the synthesis of magnetic nanoparticles. Nature Communications, 10(1). View this article in WRRO
- A biomimetic magnetosome: formation of iron oxide within carboxylic acid terminated polymersomes. Nanoscale, 11(24), 11617-11625.
- Enhanced Tubulation of Liposome Containing Cardiolipin by MamY Protein from Magnetotactic Bacteria. Biotechnology Journal. View this article in WRRO
- Draft Genome Sequence of Magnetovibrio blakemorei Strain MV-1, a Marine Vibrioid Magnetotactic Bacterium. Genome Announcements, 4(6), e01330-16-e01330-16. View this article in WRRO
- Manufacturing Man-Made Magnetosomes: High-Throughput In Situ Synthesis of Biomimetic Magnetite Loaded Nanovesicles. Macromolecular Bioscience, 16(11), 1555-1561. View this article in WRRO
- Macromol. Biosci. 11/2016. Macromolecular Bioscience, 16(11), 1736-1736.
- Biomagnetic recovery of selenium: Bioaccumulating of selenium granules in magnetotactic bacteria. Applied and Environmental Microbiology, 82(13), 3886-3891. View this article in WRRO
- Crystallizing the function of the magnetosome membrane mineralization protein Mms6. Biochemical Society Transactions, 44(3), 883-890. View this article in WRRO
- Nano- and micro-patterning biotemplated magnetic CoPt arrays. Nanoscale, 8(22), 11738-11747. View this article in WRRO
- Ferrous Iron Binding Key to Mms6 Magnetite Biomineralisation: A Mechanistic Study to Understand Magnetite Formation Using pH Titration and NMR Spectroscopy. Chemistry - A European Journal, 22(23), 7885-7894. View this article in WRRO
- Using a biomimetic membrane surface experiment to investigate the activity of the magnetite biomineralisation protein Mms6. RSC Advances, 6(9), 7356-7363. View this article in WRRO
- A novel design strategy for nanoparticles on nanopatterns: interferometric lithographic patterning of Mms6 biotemplated magnetic nanoparticles. Journal of Materials Chemistry C, 4(18), 3948-3955. View this article in WRRO
- Synthesis of ABA Tri-Block Co-Polymer Magnetopolymersomes via Electroporation for Potential Medical Application. Polymers, 7(12), 2558-2571. View this article in WRRO
- ChemInform Abstract: Novel Methods for the Synthesis of Magnetic Nanoparticles. ChemInform, 46(49), no-no.
- In situ formation of magnetopolymersomes via electroporation for MRI. Scientific Reports, 5. View this article in WRRO
- Phage display selected magnetite interacting Adhirons for shape controlled nanoparticle synthesis. Chem. Sci., 6(10), 5586-5594. View this article in WRRO
- Bioinspired nanoreactors for the biomineralisation of metallic-based nanoparticles for nanomedicine. Phys. Chem. Chem. Phys., 17(24), 15508-15521. View this article in WRRO
- Self-assembled MmsF proteinosomes control magnetite nanoparticle formation in vitro. Proceedings of the National Academy of Sciences, 111(45), 16094-16099. View this article in WRRO
- An accommodating host. Nature Nanotechnology, 9(3), 163-164.
- ChemInform Abstract: Biomimetic Synthesis of Materials for Technology. ChemInform, 44(40), no-no.
- Biomimetic synthesis of materials for technology. Chemistry - A European Journal, 19(27), 8710-8725.
- Reply to the 'Comment on "innovation through imitation: Biomimetic, bioinspired and biokleptic research"' by M. Drack and I. C. Gebeshuber, Soft Matter, 2013, 9, DOI: 10.1039/c2sm26722e. Soft Matter, 9(7), 2341-2342.
- Innovation through imitation: Biomimetic, bioinspired and biokleptic research. Soft Matter, 8(25), 6675-6679.
- Protein and peptide biotemplated metal and metal oxide nanoparticles and their patterning onto surfaces. Journal of Materials Chemistry, 22(25), 12423-12434.
- Highest levels of Cu, Mn and Co doped into nanomagnetic magnetosomes through optimized biomineralisation. Journal of Materials Chemistry, 22(24), 11919-11921.
- Fabrication of lipid tubules with embedded quantum dots by membrane tubulation protein. Small, 8(10), 1590-1595.
- Nanomagnetic arrays formed with the biomineralization protein Mms6. Journal of Nano Research, 17, 127-146.
- Biotemplated magnetic nanoparticle arrays. Small, 8(2), 204-208.
- Charge modified cowpea mosaic virus particles for templated mineralization. Advanced Functional Materials, 21(21), 4137-4142.
- Magnetic bacterial protein Mms6 controls morphology, crystallinity and magnetism of cobalt-doped magnetite nanoparticles in vitro. Journal of Materials Chemistry, 21(39), 15244-15254.
- Iron uptake kinetics and magnetosome formation by magnetospirillum gryphiswaldense as a function of pH, temperature and dissolved iron availability. Geomicrobiology Journal, 28(7), 590-600.
- Simultaneously discrete biomineralization of magnetite and tellurium nanocrystals in magnetotactic bacteria. Applied and Environmental Microbiology, 76(16), 5526-5532.
- Cell division in magnetotactic bacteria splits magnetosome chain in half. Journal of Basic Microbiology, 50(4), 392-396.
- Tetrahedral and square planar Ni[(SPR
2) 2N] 2complexes, R = Ph &iPr revisited: Experimental and theoretical analysis of interconversion pathways, structural preferences, and spin delocalization. Inorganic Chemistry, 49(11), 5079-5093.
- Cobalt uptake and resistance to trace metals in comamonas testosteroni isolated from a heavy-metal contaminated site in the Zambian Copperbelt. Geomicrobiology Journal, 27(8), 656-668.
- Cobalt uptake and resistance to trace metals in Comamonas testosteroni isolated from heavy-metal contaminated sites in the Zambian Copperbelt. GEOCHIMICA ET COSMOCHIMICA ACTA, 73(13), A1127-A1127.
- Diverse magnetic and electrical properties of molecular solids containing the thiazyl radical BDTA. Inorganica Chimica Acta, 361(14-15), 3761-3770.
- Controlled cobalt doping of magnetosomes in vivo. Nature Nanotechnology, 3(3), 158-162.
- Rapid magnetosome formation shown by real-time x-ray magnetic circular dichroism. Proceedings of the National Academy of Sciences of the United States of America, 104(49), 19524-19528.
- Controlled formation of magnetite crystal by partial oxidation of ferrous hydroxide in the presence of recombinant magnetotactic bacterial protein Mms6. Biomaterials, 28(35), 5381-5389.
- Structural and magnetic properties of [BDTA]
2[MCl 4] [M = Cu (1), Co (2), and Mn (3)], revealing an S = 1/2 square-lattice antiferromagnet with weak magnetic exchange. Inorganic Chemistry, 45(15), 5767-5773.
- Synthesis, structure, and magnetic properties of [dithiazolylium]
x[M(tdas) 2] salts. Molecular Crystals and Liquid Crystals, 452(1), 123-135.
- Structural, spectroscopic and magnetic properties of M[R
2P(E)NP(E)R′ 2] 2complexes, M = Co, Mn, e = S, Se and R, R′ = Ph or iPr. Covalency of M-S bonds from experimental data and theoretical calculations. Dalton Transactions(19), 2301-2315.
- A unique new multiband molecular conductor: [BDTA][Ni(dmit)
2] 2. Chemical Communications(25), 3204-3206.
- [BDTA](2)[Cu(mnt)(2)]: An almost perfect one-dimensional magnetic material. INORGANIC CHEMISTRY, 44(3), 546-551.
2[Cu(mnt) 2]: An almost perfect one-dimensional magnetic material. Inorganic Chemistry, 44(3), 546-551.
- Ethylenediamine Series as Additives to Control the Morphology of Magnetite Nanoparticles. Green Chemistry.
- Taking a hard line with biotemplating: cobalt-doped magnetite magnetic nanoparticle arrays. Nanoscale, 7(16), 7340-7351. View this article in WRRO
- Biopolymer Stabilization/Solidification of Soils: A Rapid, Micro-Macro, Cross-Disciplinary Approach. Environmental Science & Technology.
- Magnetosomes and Magnetosome Mimics: Preparation, Cancer Cell Uptake and Functionalization for Future Cancer Therapies. Pharmaceutics, 13(3), 367-367.
- Biological Magnetic Materials and Applications Springer Singapore
- Novel methods for the synthesis of magnetic nanoparticles In Binns C (Ed.), Nanomagnetism: Fundamentals and Applications Elsevier
- Biosynthesis of Magnetite by Microbes, Neutron Applications in Earth, Energy and Environmental Sciences (pp. 595-618). Springer US
- Biomineralisation of magnetite nanoparticles by microbes In Liang L, Rinaldi R & Schober H (Ed.), Neutron Applications in Earth, Energy, and Environmental Sciences (pp. 595-619). Springer
- Magnetosomes: Bacterial Biosynthesis of Magnetic Nanoparticles and Potential Biomedical Applications Wiley-VCH Verlag GmbH & Co. KGaA
Conference proceedings papers
- Abstract LB-188: Breast cancer immunotherapy using magnetized HSV1716. Immunology
- Abstract LB-188: Breast cancer immunotherapy using magnetized HSV1716. Immunology
- Production of magnetic nanoparticle arrays on surfaces from solution using top-down patterning and bottom-up biotemplating for future nanodevices. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 256
- Breast cancer immunotherapy using magnetised oncolytic viruses. European Journal of Cancer, Vol. 92 (pp S4-S4)
- The biomineralisation protein Mms6, and the development of a new approach to data storage. Proceedings of the World Congress on New Technologies
- Biomimetic synthesis of magnetosomes for MRI application. Proceedings of the World Congress on New Technologies
- Biotemplating Magnetic Nanoparticles on Patterned Surfaces for Potential Use in Data Storage. MRS Proceedings, Vol. 1569 (pp 231-237)