Simon JonesProf. Simon Jones

Professor of Chemistry

Room: C78

Tel: +44-(0)114-22-29483

Fax: +44-(0)114-22-29346

email:

 


 

Biographical Sketch

Prof. Jones obtained a BSc in Chemistry from the University of Southampton (1991). After obtaining his PhD from the University of Wales, Cardiff in 1995, he became a postdoctoral research associate at Arizona State University. Between 1996 and 1998 he was a postdoctoral research assistant in the Dyson Perrins Laboratory at the University of Oxford. In 1999 he was appointed to a lecturership at the University of Newcastle upon Tyne. In 2003 he moved to the University of Sheffield, where he was promoted to Senior Lecturer in 2005 and Reader in 2013. He was promoted to Professor in 2017.

Awards

Senate Teaching Award 2008.

Professional Qualifications & Memberships

CChem; FRSC

Research Keywords

Organic synthesis, asymmetric synthesis, Diels-Alder reactions, phosphorylation, organo-phosphorus chemistry, oxazaborolidine reduction, catalysis.

Teaching Keywords

Organic Chemistry

Selected Publications:

Research Interests

Image of Research Simon Jones

Methods for Asymmetric Synthesis

A major theme of a majority of my research is the development of new ways to construct molecules in a controlled and selective fashion. We have established innovative methods based on chiral anthracene templates, organocatalysts and organo-boron and phosphorus species.

Construction of Molecular Probes of Biologically Active Molecules

A number of projects are underway that involve the synthesis of new, functional molecules that can be used to probe biochemical pathways. Current projects involve the development of new magnetic imaging contrast agents, fluorescent probes based upon fatty acids and bisphosphonates, and 13C labeled anti-cancer agents for use in dynamic nuclear polarisation studies.

Synthesis of Biologically Active Molecules

Several projects are underway involving the design, synthesis, and biological testing of molecules that could be used as potential novel anti-inflammatory agents and antibiotics. Another project is similarly looking at ways to develop a new herbicide.

Teaching Section

Organic Chemistry

Undergraduate Courses Taught

  • Organic Chemistry 1 (Year 1)
    This segment introduces basic concepts for describing structure and reactivity in organic compounds.
  • Problem solving in organic chemistry (Year 3)
    Summarises Year 1 and 2 organic chemistry and practises using this knowledge with more integrated problems.

Tutorial & Workshop Support

  • Second Year Organic Chemistry Tutorials

Laboratory Teaching

  • Third Year Advanced Practical Chemistry Techniques
  • Fourth Year Research Project.

Journal articles

Chapters

  • Jones S (2008) Phosphorylation, Biotechnology: Second, Completely Revised Edition (pp. 221-241).

Conference proceedings papers

  • Warner CJA & Jones S (2012) Enantioselective preparation of P-chiral phosphine oxide organocatalysts and their application in asymmetric synthesis. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 243
  • Jones S & Crook S (2008) ORGN 47-Synthesis and application of N-phosphoryl oxazolidinones to asymmetric phosphorylation. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 236
  • Jaunet A, Jones S & Poinsard C (2007) ORGN 638-Use of chiral anthracene templates for the synthesis of cyclohexene monoepoxide natural products. ABSTR PAP AM CHEM S, Vol. 234
  • Burgin RN, Jones S, Smith A & Tarbit B (2007) ORGN 752-Construction of the quinoline ring system by application of minisci radical cyclization. ABSTR PAP AM CHEM S, Vol. 234
  • Jones S & Marsh B (2006) ORGN 121-The effect of the nitrogen substituent on enantioselectivity of the catalytic asymmetric reduction of meso-imides with chiral oxazaborolidine catalysts. ABSTR PAP AM CHEM S, Vol. 232
  • Rolfe A & Jones S (2005) Chiral nucleophilic podand catalysts for asymmetric phosphoryl transfer.. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 229 (pp U547-U548)
  • Jones S, Rolfe A & Wilson I (2004) Methods for chemical asymmetric phosphoryl transfer.. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 227 (pp U202-U202)
  • Norton HC & Jones S (2004) Asymmetric catalysis utilising imidazoles. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 227 (pp U181-U181)
  • Gilmore NJ & Jones S (2004) Asymmetric reduction with aminoindanol based oxazaborolidines. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 227 (pp U181-U181)
  • Jones S & Toms SM (2002) Studies towards the synthesis of the potent antibiotic agent sarcophytolide.. ABSTR PAP AM CHEM S, Vol. 224 (pp U201-U201)
  • Jones S & Dixon RA (2002) Asymmetric reduction of amides and meso-imides using chiral oxazaborolidine catalysts.. ABSTR PAP AM CHEM S, Vol. 224 (pp U202-U202)
  • Jones S (2002) Photoactivated chiral auxiliaries based upon functionalised anthracene derivatives.. ABSTR PAP AM CHEM S, Vol. 224 (pp U250-U251)
  • KELLY DR, HARRISON SJ, JONES S, WADDING A, MAZOMENOS BE & RAPTOPOULOS D (1995) The synthesis and biological activity of analogues of 1,7-dioxaspiro-[5.5]undecane. The pheromone of the olive fly (Bactrocera oleae). INTEGRATED CROP PROTECTION: TOWARDS SUSTAINABILITY?(63) (pp 387-394)