PhD Project


Periodontal Treatment and Oral Health Related Quality of Life

PhD Student: Andrew Rawlinson, BChD(Hons), MDS, FDSRCSEd. Professor of Restorative Dentistry. Staff candidate

Supervisors: Dr Mario Vettore, Professor Sarah Baker and Professor Peter Robinson

Outline of research: Destructive periodontal diseases are common in adults in the UK, with 37% of individuals having mild periodontal pocketing, 8% having moderate and 1% having severe periodontal pocketing (White et al., 2012). The cost of treating periodontal conditions presents a significant financial burden to patients affected and the UK NHS, where it is has been estimated that approximately £250 million per year is spent on treatment. The total cost to the economy has been calculated at £2.8billion, including time off work, lost UK revenue etc (Chapple, 2004).

Until relatively recently, the outcomes of health interventions in the management of periodontal diseases have largely been measured with clinical parameters. These measures have demonstrated that treatment can improve the clinical condition (Cobb, 2002), but ignore the effect of periodontal disease and its treatment on psychological and social well being of individuals.

This research will investigate individual factors including sense of coherence, self-efficacy, self-esteem and locus of control that may influence oral hygiene behaviours, adherence to treatment regimens, coping with stress and health beliefs. In doing so, they may influence the clinical and OHQoL outcomes of care. The Wilson and Cleary model (Wilson and Cleary, 1995) will be used to enable comprehensive research on this topic. 

Recent publications:

  • Gonçalves P. C. G., Griffiths G., Rawlinson A. A Study of the Periodontal State of a Late Medieval United Kingdom Population. Achieves of Oral Biology, 2015, 60(12):1797-1801.

  • Qasim SB, Delaine-Smith RM, Fey T, Rawlinson A, Rehman I. Freeze gelated porous membranes for periodontal tissue regeneration. Acta Biomaterialia, 2015, 23:317-328 . Doi:10.1016/j.actbio.2015.05.001

  • Berahim Z., Moharamzadeh K, Jowett AK, Rawlinson A. Evaluation of Osteogenic and Cementogenic Potential of Periodontal Ligament Fibroblast Spheroids Using a Three-Dimensional In Vitro Model of Periodontium. International Journal of Dentistry, 2015, http://dx.doi.org/10.1155/2015/605813.

  • Berahim Z, Moharamzadehd K, Rawlinson A, Jowett AK. Characterization of periodontal spheroids in vitro. Chiang Mai Journal of Science 2013;40(6):1020-1029.

  • Bakri I, Douglas CWI, Rawlinson A. The effects of stress on periodontal treatment: a longitudinal investigation using clinical and biological markers. Journal of Clinical Periodontology 2013;40:995-961.

  • Jowett A, Marlow I, Rawlinson A. A Double Blind Randomised Controlled Clinical Trial Comparing a Novel Anti-stain and Calculus Reducing Dentifrice with a Standard Fluoride Dentifrice. Journal of Dentistry 10.1016/j.jdent.2012.12.005. [Epub ahead of print] Journal of Dentistry 41(2013) 313-320.

  • Zheng X, Cook JP, Watkinson M, Yang S, Douglas I, Rawlinson A, Krause S. Generic protease detection technology for monitoring periodontal disease. Faraday Discussions 2010;149:1-11.

  • Berahim Z, Moharamzadeh, Rawlinson A, Jowett AK. Biological interaction of 3D periodontal fibroblast spheroids with collagen-based and synthetic membranes Journal of Periodontology 2011:82;790-7.

  • Jowett AK, Orr MTS, Rawlinson A, Robinson PG. Psychosocial impact of periodontal disease and its treatment with 24-h root surface debridement. Journal of Clinical Periodontology 2009;36: 413–418.