We are elucidating the complex processes that underpin the emergent behaviour of molecular networks and how these coalesce to generate the robust properties that define life through cells to populations. We work across bacteria, fungi, plants, animals and humans, not only studying them alone but also how they interact to shape each other’s destinies and behaviour.
We study how life develops and functions throughout its course in health and disease, how it evolves across the generations and the effect of technological, behavioural, and clinical interventions designed to improve key outcomes such as wellbeing.
We have a total of £48 million in grant income in this area. This success is mediated by world-class facilities and an interconnected network of interdisciplinary institutes and centres including:
The next generation of microscopy technology
Researchers in the Imagine: Imaging Life institute are using the latest advanced microscopy tools to shed new light on life and disease. Their expertise in atomic force, cryo-electron and optical microscopy has forged a unique centre of excellence for microscopy.
New hope in search for motor neuron disease treatment
Professor Sherif El-Khamisy led a study into the genetic and cellular malfunctions that lead to the symptoms of motor neuron disease. It found that the most common genetic cause of the illness was when part of a gene called C9orf72 repeated, making the patient's DNA become unstable and break.
Understanding autism spectrum conditions in adulthood
Dr Elizabeth Milne led a major project to develop a deeper understanding of people with autism spectrum conditions, particularly those diagnosed in adulthood. She also ran a series of events to help the public better understand the autism spectrum.
Brain tingles: First study of its kind reveals physiological benefits of ASMR
In a groundbreaking study, Dr Guilia Poeiro found that those who experience Autonomous Sensory Meridian Response, or 'brain tingles', had significantly reduced heart rates while watching ASMR videos compared to people who do not experience ASMR.