Dr Emma Boldock MB BS MA (Hons) Cantab MSc MRCP FRCPath PhD
NIHR Academic Clinical Lecturer in Microbiology
Department of Infection, Immunity & Cardiovascular Disease
University of Sheffield
Beech Hill Road
Tel: +44 (0)114 215 9522
I completed my undergraduate medical training in 2007 and after general medical and surgical rotations in London, moved to Sheffield for higher specialist training in Medical Microbiology. I obtained an NIHR Academic Clinical Fellowship in 2011 and was awarded a Wellcome Trust Clinical Research Training Fellowship (2013-2016) under the supervision of Professor Simon Foster and Professor Stephen Renshaw, investigating Staphylococcus aureus virulence.
After completing my PhD, I was appointed to NIHR Academic Clinical Lecturer (2016) in the Department of Infection, Immunity and Cardiovascular Disease. I am an Honorary Specialist Training Registrar in Microbiology at Sheffield Teaching Hospitals NHS Foundation Trust.
My main research interest focuses on understanding the initial stages of Staphylococcus aureus infection and the role of surrounding commensal flora.
Models of S. aureus infection require a high inoculum, thought to be due to allowing bacteria to be able to compete in vivo. However, previous work has demonstrated that only a few bacteria, from the inoculum, succeed in passing through an immunological bottleneck and causing infection. Thus, I am interested in understanding the role of the rest of the inoculum. Infection of humans will always occur via a polymicrobial inoculum and improved understanding of these processes will have clinical translation.
I help to deliver the undergraduate (MBChB) Microbiology/Infection curriculum at the University of Sheffield and postgraduate regional infection teaching for Core Medical and Higher Specialist Trainees at Sheffield Teaching Hospitals.
- Member of Hospital Infection Society (HIS) Council (2016 to date)
- Trainee representative on Yorkshire Specialist Training Committee for Microbiology (2016 to date)
- Vice Chair of Trainees Advisory Committee, The Royal College of Pathologists (2012-2014)
- Trainee representative on Academic Activities and Conferences Committee, The Royal College of Pathologists (2010-2012)
- to elucidate in vivo mechanisms of S. aureus infection and how this is effected by the surrounding microflora
- to identify S. aureus components required for growth on human blood and disease
N.B. Emma Boldock (née Johnson)
- Connolly J, Boldock E, Prince LR, Renshaw SA, Whyte MK & Foster SJ (2017) The identification of Staphylococcus aureus factors required for pathogenicity and growth in human blood.. Infect Immun. View this article in WRRO
- Di Bella S, Friedrich AW, García-Almodóvar E, Gallone MS, Taglietti F, Topino S, Galati V, Johnson E, D'Arezzo S & Petrosillo N (2015) Clostridium difficile infection among hospitalized HIV-infected individuals: epidemiology and risk factors: results from a case-control study (2002-2013).. BMC Infect Dis, 15, 194. View this article in WRRO
- Forhead AJ, Jellyman JK, De Blasio MJ, Johnson E, Giussani DA, Broughton Pipkin F & Fowden AL (2015) Maternal Dexamethasone Treatment Alters Tissue and Circulating Components of the Renin-Angiotensin System in the Pregnant Ewe and Fetus. Endocrinology, 156(8), 3038-3046.
- Di Bella S, Taglietti F, Iacobuzio A, Johnson E, Baiocchini A & Petrosillo N (2015) The “Delivery” of Adam. Mayo Clinic Proceedings, 90(4), 505-508.
- Di Bella S, Capone A, Musso M, Giannella M, Tarasi A, Johnson E, Taglietti F, Campoli C & Petrosillo N (2013) Clostridium difficile infection in the elderly.. Infez Med, 21(2), 93-102.
- Di Bella S, Paglia MG, Johnson E & Petrosillo N (2012) Clostridium difficile 027 infection in Central Italy. BMC Infectious Diseases, 12. View this article in WRRO
- Johnson E, Giri P & Parsons HK (2012) Role of occupational health staff in investigation of invasive group A streptococcal infection hospital outbreak. Journal of Hospital Infection, 81(3), 199-201.
- Di Bella S, Capone A, Bordi E, Johnson E, Musso M, Topino S, Noto P & Petrosillo N (2011) Salmonella enterica ssp. arizonae infection in a 43-year-old Italian man with hypoglobulinemia: A case report and review of the literature. Journal of Medical Case Reports, 5. View this article in WRRO
- di Bella S, Capone A, Olearo F, Johnson E, Chinello P, Baiocchini A, del Nonno F, Rizzi EB & Petrosillo N (2011) Vertebral lesions from AIDS-related Kaposi's sarcoma. Current HIV Research, 9(4), 270-275.
Conference proceedings papers
- Johnson E, Wagner N, Williams A, Prajsnar T, Renshaw S & Foster S (2015) Co-operation during Staphylococcus aureus pathogenesis. Journal of Infection, Vol. 71(6) (pp 684-684)
Theses / Dissertations
- Boldock E (2016) Analysis of Staphylococcus aureus virulence.