Professor Anne Goodeve BSc PhD

Professor of Molecular Medicine

Department of Infection, Immunity & Cardiovascular DiseaseAnne Goodeve
University of Sheffield
Medical School
Beech Hill Road
Sheffield
S10 2RX

Telephone: +44 (0)114 215 9528 / 271 7005
Fax: +44 (0)114 271 1863
Email: a.goodeve@sheffield.ac.uk

Secretary: Mrs Vicky Cottam
Tel: +44 (0) 114 215 9504
Email: vicky.cottam@sheffield.ac.uk

Biography:

I joined the University of Sheffield in 2001, having previously been closely associated with the organisation for several years as an honorary lecturer. My background is in molecular biology and genetics of haematological disorders. Following a PhD and postdoctoral position working on a viral genetics, I began investigation of the molecular pathogenesis of inherited haemostatic disorders in 1990 and spend my time equally between the University and on diagnostic aspects of this work at Sheffield Diagnostic Genetics Service.

Research Interests:

My work is aimed at understanding the pathogenesis of the inherited bleeding disorder, von Willebrand disease. Current work is focussed on determination of the contribution of genetic variation in the von Willebrand factor (VWF) gene, ABO blood group and other non-VWF loci on low plasma VWF level and symptoms of bleeding.

Current Projects:

Zimmerman Program on the Molecular and Clinical Biology of von Willebrand Disease, a National Institute for Health funded Program Project Grant in collaboration with Bob Montgomery, Milwaukee and David Lillicrap, Kingston Ontario.

Type 3 Von Willebrand International Registries Inhibitor Prospective Study in collaboration with Augusto Federici, Milan.

Professional Activities:

  • British Society on Haemostasis and Thrombosis; Committee member and Treasurer.
  • EU von Willebrand Disease Co-operative Group Co-chair.
  • von Willebrand Disease; From Theory to Clinical Practice annual clinical teaching meeting in Malmo; member of Faculty.
  • Istituto di Ricerche Farmacologiche Mario Negri, Ranica near Bergamo Italy; Open University external PhD supervisor.
  • Member of the United Kingdom National External Quality Assessment Survey (UK NEQAS) Specialist Advisory Group on Haemostasis Genetics.
  • Co-opted member of the World Federation for Hemophilia Laboratory Science Committee.
  • Member of the European Association for Haemophilia and Allied Disorders locus specific mutation database curators working group.
  • Member of the editorial board of the journal Haemophilia.
  • Member of the editorial board of the Journal of Thrombosis and Haemostasis.

Publications:

For key publications see below. For a full list of publications click here.

Journal articles

Chapters

  • Goodeve AC & Peake IR (2012) Laboratory analysis of von Willebrand disease: Molecular analysis In Kitchen S, Olson JD & Preston FE (Ed.), Quality in Laboratory Hemostasis and Thrombosis Wiley-Blackwell