Dr. Robert Wilkinson BSc MSc DPhil

Research FellowRobert Wilkinson

Address:
Department of Infection, Immunity & Cardiovascular Disease
University of Sheffield
Medical School
Beech Hill Road
Sheffield
S10 2RX
Tel: +44 (0) 114 226 1201
Fax: +44 (0) 114 271 1863
Email: robert.wilkinson@sheffield.ac.uk

Secretary: Mrs Susan Clary
Tel: +44 (0) 114 215 9503
Email: s.clary@sheffield.ac.uk

Biography:

I graduated from the University of Leeds with a BSc in Biology in 2001 and an MSc in Human Genetics in 2002. After a research position at the University of Manchester, I joined Prof. Roger Patient’s lab on an MRC studentship at the MRC Molecular Haematology Unit, Weatherall Institute for Molecular Medicine, University of Oxford. During my DPhil I studied the embryonic signals that regulate arterial differentiation and blood stem cell formation in the zebrafish. I joined the University of Sheffield in 2008 as a Wellcome Trust Postdoctoral Fellow with Dr. Freek van Eeden, in the MRC Centre for Biomedical and Developmental Genetics, studying the formation of arteries and veins. I moved to the Department of Cardiovascular Science in 2013 to establish an independent research group.

Research Interests:

My research focuses on two important areas of vascular biology; firstly, unravelling the molecular and genetic mechanisms governing blood vessel formation and maturation as a strategy to combat cardiovascular disease. Secondly, we are characterising the genetic mechanisms which underlie blood stem cell formation from the embryonic artery. Exploiting the processes of angiogenesis and stem cell formation are key strategies in regenerative cardiovascular medicine. We currently employ the zebrafish as a model system to study these processes.

Transgenic_zebrafish

 

 

Current Projects:

  • Characterisation of the mechanisms which regulate blood vessel formation, stability and maturation.
  • Transcriptional programming of zebrafish HSC formation.

Professional Activities:

Publications:

For key publications see below. For a full list of publications click here.

Journal articles