Array design for lead optimisation in pharmaceutical research

Aim: To investigate and develop tools to assist medicinal chemists in the design of compound arrays during the lead optimisation stage of drug discovery. Lead optimisation is a complex, time-consuming task which chemists use to carry out to identify a candidate molecule to progress to clinical trials.

Sponsor: GlaxoSmithKline

Principal Investigator: Val Gillet
Co-investigators: Peter Willett