The University of Sheffield is an internationally leading centre of excellence in biology, with world-class research facilities. Biology at Sheffield was ranked 5th in the UK in the 2014 REF, and Subjects Allied to Medicine was ranked 1st in the UK. We are now looking to recruit Independent Research Fellows as the potential academic leaders of the future. We host many research fellows, and have an excellent record of converting Fellowships to permanent academic positions.
Funding agencies include BBSRC, CRUK, NERC, The Leverhulme Trust, MRC, The Wellcome Trust and The Royal Society. We invite outstanding researchers who either hold, or intend to apply for, an Independent Fellowship to visit and discuss their future career paths. After the visit we will mentor and assist selected applicants in submitting their Fellowship applications.
The Department of Molecular Biology and Biotechnology has internationally recognised research foci spanning Molecular Cell Biology, Structural Biology, Microbiology and Molecular Genetics. In particular we foster multidisciplinary approaches to tackle long term biological problems with exceptional interactions across biology, physics, chemistry, medicine and beyond. MBB is a friendly department, doing consistently well in the National Student Survey.
We encourage a highly collaborative spirit between research groups in a supportive and helpful environment in which we work hard to support and mentor young scientists through their early career. Currently 30% of our staff have been through the Independent Research Fellows career route. We will provide successful applicants with a postgraduate studentship and modern refurbished laboratory space of the highest standard within the University’s historic Firth Court Building (where Hans Krebs carried out much of his Nobel Prize-winning research into cellular metabolic cycles).
Fellowship case studies
Dr Rebecca Corrigan
Royal Society/Wellcome Trust Sir Henry Dale Research Fellow
Dr Rebecca Corrigan, who studied first at Trinity College Dublin, before doing post-doctoral research at Imperial College London was awarded a Sir Henry Dale Research Fellowship in 2016. The scheme provides support for postdoctoral researchers who aim to become independent scientists leading their own groups.
Rebecca, is a molecular microbiologist interested in the study of the cell-signalling and virulence mechanisms of the Gram-positive pathogen Staphylococcus aureus. Her recent work has led to the development of a genome-wide approach to analyse nucleotide-protein interactions. Rebecca aims to use this methodology, in conjunction with biochemical assays, to identify binding targets for (p)ppGpp, nucleotides that are involved in promoting persistent and recurrent infections. The mapping of the (p)ppGpp signalling network will provide a greater understanding of how S. aureus can persist in the human host, enabling rational drug design.
“What attracted me to Sheffield is the remarkable mixture of biochemists, microbiologists, structural biologists, all working together in my department (MBB - the Department of Molecular Biology and Biotechnology). This makes collaborations incredibly easy and so conducive to multidisciplinary research. The unique approach to research of the Florey Institute, which combines clinicians and researchers under one umbrella, was just the icing on the cake.”
Dr Dan Bose
Sheffield Institute for Nucleic Acids (SInFoNiA) Research Fellow
Dr Dan Bose completed his PhD in 2008 at Imperial College London, before working as a Postdoctoral Researcher first in London and then between 2011 and 2016 at the Pennsylvania in Philadelphia in Prof. Shelley Berger’s lab. He was awarded a SInFoNIA Research Fellowship in 2017.
"I joined the department of Molecular Biology and Biotechnology in April 2017 following a postdoc at the University of Pennsylvania in Philadelphia. Starting my own group was a big step, and I wanted to make sure that I was in the best possible place for my group to grow and flourish. The breadth of research within Molecular Biology and Biotechnology made it a fantastic place for me to join. The world class facilities and expertise provided by Molecular Biology and Biotechnology to support my research goals was a big factor in my choice to come here; my work is multidisciplinary, incorporating biochemistry, cell biology, cryo-EM and functional genomics and Molecular Biology and Biotechnology has provided an superb and supportive environment in which to start my lab. The department has a vibrant community of experienced and early career researches, ensuring a great balance between established expertise and energetic, exciting and motivated junior faculty scientists. The research community feels very dynamic and ‘buzzy’ - we meet up regularly and are very collaborative. This has allowed me to rapidly incorporate new techniques into my research, that have significantly strengthened my work.
"I didn’t know much about Sheffield before starting my group, but since moving here I’ve discovered that it's a fantastic city to live in (but one that people like to keep a closely guarded secret!). There is a very vibrant arts and music scene and some fantastic restaurants; the city is affordable and there is great childcare and schools. One of the biggest benefits is how close we are to beautiful countryside. My house is ten minutes from the peak district national park, meaning I can pop to lab on a Saturday morning and be in open country in the afternoon; the opportunities for walking, climbing and cycling are seemingly endless. For me, having spent so long in big cities this was truly life-changing!
"Starting your own group is an exciting and sometimes scary time. Choosing to start my group at the department of Molecular Biology and Biotechnology is one of the best decisions I’ve made. There are so many opportunities and avenues to explore that have been made possible by being here, and the department has given me all the freedom and support that I need to successfully establish my research group."