|Computational Models for Virtual Cerebral Aneurysm Coiling|
|Supervisor: Professor Alejandro Frangi|
Coiling is the most widespread endovascular treatment for intracranial aneurysms. It consists of the placement of metal wires inside the aneurysm to promote blood coagulation. This project aims at developing a virtual coiling technique for pre-interventional planning and post-operative assessment of coil embolisation procedure of aneurysms. The goal is to develop an algorithm that mimics coil insertion inside a 3D aneurysm model, which allows the estimation of a plausible distribution of coils within a patient-specific anatomy.
In previous work we have proposed a method for virtual deployment of coils using a path-planning approach. This strategy allowed us to virtually deploy coils in realistic patient-specific anatomies of cerebral aneurysms and to explore the hemodynamic implications of coil configurations. However, there are still a number of issues to be explored, in particular to understand the role of coils in affecting hemodynamics in various anatomical configurations.
The project aims to: a) analyse the literature extensively thus providing an overview of the mechanical properties of real coils and their known behaviour; b) review existing literature on models for virtual coiling and critically analyse and understand to what extent they reproduce the known behaviour; c) propose extensions to our framework that are more realistic and comprehensive with respect to coil behaviour; d) implement the new model and demonstrate its applicability in a database of image-based cerebral aneurysms from 3D rotational angiography and understanding the hemodynamic properties of aneurysms before and after embolisation with coils.