Mechanobiology of growth and adaptation
Supervisor: Professor Marco Viceconti

At birth, human skeleton is mostly made of cartilage, and very coarsely defined; as the infant moves bones develop, mineralise, and assume their final shape. The process continues even during adulthood; every ten years our skeleton is completely destroyed and recreated by a constant repair-adaptation process. Skeletal growth and skeletal adaptation are regulated by biomechanical stimuli; for example, astronauts who live in weightlessness for long periods can lose 30% of the total bone mass. The PhD candidate will join Prof Viceconti research team and will develop a computational model that explore some current theories on the mechanoregulation of bone growth and adaptation.

Previous experience / requirements: good understanding of solid mechanics and finite element analysis

For more information contact: m.viceconti@sheffield.ac.uk