Multiscale modelling of the skeleton
Supervisor: Professor Marco Viceconti

The strength of a bone change constantly because the tissue that compose it is modified by the living cells that permeate it. Any quantitative model of bone growth adaptation requires we model the mechabiology of bone cells regulation (which occurs at the scale of 1-10 micrometres, and over a time scale of seconds), coupled with the cell-tissue interaction (which occurs at the scale of 0.1-1.0 millimetre, and over a time scale of months), and the effect that tissues changes on the biomechanical strength of whole bones (which occurs at the scale of 0.5 metres, while fragile bone fractures propagate in milliseconds). The PhD candidate will join Prof Viceconti research team and will develop new methods to model the biomechanics of the human skeleton across these radically different space-time scales.

Previous experience / requirements: good understanding of solid mechanics, some element of software programming

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