Sub-optimal control of muscles activation in neurodegenerative diseases
Supervisor: Professor Marco Viceconti

In a normal healthy adult, during physiological activities such as walking the central nervous system fire the muscles in an optimal pattern that minimise the energy expenditure. However, if one has a painful knee, or a particularly weak group of muscles, the central nervous system must resort to sub-optimal muscle activation strategies, which try to minimise the load transmitted through that knee, or the force expressed by that group of muscles. The PhD candidate will join Prof Viceconti research team and will develop a computational model of neuromuscular activation capable of exploring these sub-optimal control patterns, in patients affected by neurodegenerative diseases.

Previous experience / requirements: good understanding of multibody dynamics

For more information contact: m.viceconti@sheffield.ac.uk