Professor Paul Griffiths

FMedSci, PhD, FRCR

Department of Infection, Immunity and Cardiovascular Disease

Professor of Radiology

p.griffiths@sheffield.ac.uk
+44 114 215 9604

Full contact details

Professor Paul Griffiths
Department of Infection, Immunity and Cardiovascular Disease
Floor C
Royal Hallamshire Hospital
Glossop Road
Sheffield
S10 2JF
Profile

I joined the University of Sheffield as the Professor of Radiology in 1996 having held the position of Consultant Neuroradiologist at Addenbrooke’s Hospital, Cambridge since 1995.

I administer three MR scanners on behalf of the University of Sheffield and the majority of my research interests centre around neuroimaging using MR (see below). I became a Fellow of the Academy of Medical Sciences in 2008.

Research interests

My research interests are Paediatric Neuroradiology and in utero MRI scanning.

I am a neuroradiologist who has specialised in diseases of the developing brain therefore much of my clinical and academic work concerns MR imaging the brains of fetuses, neonates and children. The vast majority of my research is patient-centred and I have a good track record of delivering research that informs and changes clinical practice.

Two examples are:

  1. MR of the fetal brain. My group has been responsible for the development of this technique and has been able to assess the new technology with grants from several sources including the Wellcome Trust. This led to an award of £1.9m from SRIF 3 for a new MR facility enabling the expansion in this field and in b). We have currently undertaking an NIHR grant for £1.4m (MERIDIAN) that will allow us to complete the assessment and inform future management of pregnant women.
  2. MR of the neonatal brain. Safety is a major issue in this field and we have developed a new environment that allows safe transport of the neonate to a geographically separate MR scanner. In parallel we have been responsible for the design of a high field strength MR scanner that can be sited on a neonatal unit. The plans have been supported by the Wellcome Trust and GE Healthcare to develop and test two prototype systems, one in Boston Children’s Hospital and the other in Sheffield

Current Projects

  • MERIDIAN study – fetal brain imaging (funded by HTA)
  • Neonatal brain imaging (funded by Wellcome Trust/ GE Healthcare)
Publications

Show: Featured publications All publications

Books

  • Griffiths P, Morris J, Larroche J-C & Reeves M (2009) Atlas of Fetal and Postnatal Brain MR. Mosby. RIS download Bibtex download

Journal articles

All publications

Books

  • Griffiths PD (2010) Preface. Elsevier. RIS download Bibtex download
  • Griffiths P, Morris J, Larroche J-C & Reeves M (2009) Atlas of Fetal and Postnatal Brain MR. Mosby. RIS download Bibtex download

Journal articles

Chapters

Conference proceedings papers

  • Lie MLS, Graham RH, Robson SC & Griffiths PD (2019) Patient and Professional insights into the acceptability of in utero MRI for brain abnormalities. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 126 (pp 75-75) RIS download Bibtex download
  • Stewart NJ, Norquay G, Parra-Robles J, Marshall H, Leung G, Murphy PS, Schulte RF, Elliot CA, Condliffe R, Billings CG , Smith I et al (2015) Assessment of lung microstructure in ILD with3He and129Xe MRI. 4.1 Clinical respiratory physiology, exercise and functional imaging RIS download Bibtex download
  • Stewart N, Norquay G, Parra-Robles J, Marshall H, Leung G, Murphy P, Schulte R, Elliot C, Condliffe R, Billings C , Smith I et al (2014) P273 Assessment Of Lung Microstructure In Interstitial Lung Disease With Hyperpolarised Gas Mri. Thorax, Vol. 69(Suppl 2) (pp A192-A193) RIS download Bibtex download
  • Griffiths P (2010) Fetal MR for CNS malformations. JOURNAL OF MEDICAL GENETICS, Vol. 47 (pp S20-S20) RIS download Bibtex download
  • Fenner J, Sucharov T, Hose DR, Jones I, Griffiths P & Wilkinson I (2008) The Karman Vortex in a Medical Imaging Context: A Validated Computational Model of Laminar Shedding.. MSV (pp 185-190) RIS download Bibtex download
  • Jellinek D, Hoggard N, Wilkinson I, Levy D, Giesel F, Romanowski C, Miller B & Griffiths P (2007) Dexamethasone and enhancing gliomas: Alterations in perfusion and blood-tumor barrier kinetics shown by magnetic resonace imaging. NEURO-ONCOLOGY, Vol. 9(4) (pp 578-578) RIS download Bibtex download
  • Selvarajah D, Gandhi RA, Hunter MD, Emery CJ, Griffiths PD, Tesfaye S & Wilkinson ID (2007) A functional magnetic resonance imaging study demonstrating alterations in brain responses to acute pain stimulation in diabetic neuropathy. DIABETOLOGIA, Vol. 50 (pp S448-S449) RIS download Bibtex download
  • Davies N, Paley M, Griffiths P & Whitby E (2006) Incidence of extracranial hemorrhage in asymptomatic neonates. A MRI study evaluating mode of delivery. American Journal of Obstetrics and Gynecology, Vol. 195(6) (pp S47-S47) RIS download Bibtex download
  • Gandhi RA, Selvarajah D, Wilkinson I, Emery C, Shaw PJ, Griffiths PD & Tesfaye S (2006) Preservation of thalamic neuronal function may be a prerequisite for pain perception in diabetic neuropathy. DIABETOLOGIA, Vol. 49 (pp 119-119) RIS download Bibtex download
  • Sokhi DS, Price SE, Kitchen S & Griffiths PD (2005) Plasma D-dimer levels in intracranial venous thrombosis. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vol. 76(9) (pp 1326-1326) RIS download Bibtex download
  • Selvarajah D, Wilkinson ID, Emery CJ, Shaw PJ, Griffiths PD & Tesfaye S (2004) Spinal cord atrophy in diabetic neuropathy, a comparison with healthy volunteers and hereditary sensory motor neuropathy.. DIABETOLOGIA, Vol. 47 (pp A35-A36) RIS download Bibtex download
  • Tesfaye S, Selvarajah D, Emery CJ, Shaw PJ, Griffiths PD & Wilkinson JD (2004) Thalamic sensory neuronal dysfunction in distal symmetrical polyneuropathy. DIABETOLOGIA, Vol. 47 (pp A365-A365) RIS download Bibtex download
  • Dickson JM, Howell SJ, Griffiths P, Wilkinson I & Grunewald RA (2003) Memory performance and magnetic resonance spectroscopy of the temporal lobes in idiopathic generalised epilepsy. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vol. 74(10) (pp 1449-1450) RIS download Bibtex download
  • Selvarajah D, Wilkinson ID, Griffiths PD, Shaw PJ & Tesfaye S (2003) Early spinal cord involvement in diabetic peripheral neuropathy. DIABETOLOGIA, Vol. 46 (pp A312-A312) RIS download Bibtex download
  • Noguchi Y, Marzouqa I, Hose DR, Paley MNJ, Wilkinson ID, Fenner JW & Griffiths PD (1999) Vortex shedding observations using magnetic resonance imaging, flow visualisation and computational fluid dynamics. COMPUTATIONAL METHODS AND EXPERIMENTAL MEASUREMENTS IX (pp 223-230) RIS download Bibtex download
  • Whitby EH, Paley MN, Smith MF, Sprigg A, Teasdale K, Woodhouse N & Griffiths PD (1999) Neonatal magnetic resonance imaging. A new approach on the special care baby unit. 3RD EPNS CONGRESS (EUROPEAN PAEDIATRIC NEUROLOGY SOCIETY) (pp 47-51) RIS download Bibtex download
Teaching interests

I am involved in a number of teaching activities ranging from undergraduate lecturing, project management and mentoring through to training Europe's neuroradiogists of the future through my involvement with the European Society of Neuroradiology. I helped to establish the Academic Clinical Fellows/Lecturer programme along with my colleague, Dr Nigel Hoggard.

I supervise several PhD/MD students at a time and I have a very high completion rate of higher degree award. In 2009 I became the Chair of the academic sub-committee of the British Society of Neuroradiologists with a remit to advise on how to improve the number and quality of neuroradiologists with academic credentials.

Professional activities
  • NIHR CCRCD Panellist for Doctoral Research Fellowships 2009-
  • Member of the Diagnostic Technologies and screening panel, NHS RTA programme 2008-
  • Honorary member of the NIHR Faculty 2008-
  • Member of British Society of Neuroradiologists from 1995
  • Member of the American Society of Paediatric Neuroradiology from 2002
  • Scientific Committee member of the European Course in Neuroradiology 2006-
  • Medical Advisor to the Board of the Tuberous Sclerosis Society Association (GB)
  • Medical Advisor to the Society for Research into Hydrocephalus and Spina Bifida