Professor Rod Hose

BSc, PhD

Department of Infection, Immunity and Cardiovascular Disease

Professor of Computational Biomechanics

Medical Physics Group

d.r.hose@sheffield.ac.uk
+44 114 215 9533

Full contact details

Professor Rod Hose
Department of Infection, Immunity and Cardiovascular Disease
The Medical School
Beech Hill Road
Sheffield
S10 2RX
Profile

After graduating in Mathematics from the University of Manchester, I joined Lucas Aerospace as a graduate apprentice engineer. From 1977 to 1992 I worked as a stress engineer and as a consultant structural analyst for several companies in the aerospace, motor vehicle and general engineering sectors.

During this period I also completed my PhD in Applied Mechanics at the University of Manchester Institute of Science and Technology. I joined academia in 1992 as a lecturer in Aircraft Structures at the University of Salford.

I moved to Medical Physics at the University of Sheffield in 1994, where I was initially responsible for the development of undergraduate teaching in medical physics and had a primary research interest in the computational analysis of heart valve prostheses.

I am currently Professor of Computational Biomechanics in the Mathematics and Modelling in Medicine Group in the Department of Infection, Immunity and Cardiovascular Disease at the University of Sheffield (40% FTE) and Professor of Computational Cardiovascular Physiology in the Department of Circulation and Biomedical Engineering at NTNU in Trondhem.

I was awarded Dr Honoris Causa by the Technical University of Cluj-Napoca in 2014.

Research interests

My research interests are in the development of methods and workflows for the computational analysis of (primarily) cardiovascular systems, and in their translation to clinical application.

I am interested in all aspects of the process, from clinical data collection and management through image processing to the building of detailed three dimensional models of the vasculature and on to determination of appropriate boundary conditions, numerical solution and data reduction.

I have been intimately involved in the development of the European Commissions Virtual Physiological Human initiative from its beginning.


Current & Recent Projects

  • VPH-Share.
  • MD-Paedigree.
  • HICF Grant.
  • euHeart: Integrated Cardiac Care using Patient-Specific Cardiovascular Modeling. Funded by the European Community’s Seventh Framework Programme under the Information Society and Media’s Virtual Physiological Human initiative. Grant agreement 224495.
  • Translating Biomedical Modelling to the Heart of the Clinic Funded by the EPSRC under its Digital Economy programme in the Grand Challenges in IT for Healthcare initiative.
  • Virtual Physiological Human Network of Excellence. Funded by the European Community’s Seventh Framework Programme under the Information Society and Media’s Virtual Physiological Human initiative.
  • Collaborator with the NIHR Sheffield Cardiovascular Biomedical Research Unit
  • The Virtual Tendon: a multiscale computational model of dynamic tissue remodelling. Funded by Arthritis Research Campaign
  • @neurIST: Integrated Biomedical Informatics for Management of Cerebral Aneurysms (2006-2010), Funded by the European Community’s Sixth Framework Programme by DG-Infso.
  • EurValve
  • i4i (National Institute for Health Research, Invention for Innovation (i4i). Gunn JP, Morris PD, Hose DR, Lawford PV. ‘A prototype tool to calculate 'virtual' myocardial fractional flow reserve (vFFR) non-invasively (VIRTU-3)’. March 2017 – March 2019.
Publications

Show: Featured publications All publications

Journal articles

All publications

Books

Journal articles

Chapters

Conference proceedings papers

  • Gosling R, Morris P, Lawford P, Hose R & Gunn J (2019) Virtual (computed) FFR and Virtual Coronary Intervention (VCI) vs angiography for guiding PCI: a virtual study.. Heart, Vol. 105(Suppl 6) (pp a45-a45). Manchester, UK, 3 June 2019 - 5 June 2019. View this article in WRRO RIS download Bibtex download
  • Sciola MI, Morris PD, Lawford PV, Hose DR & Gunn JP (2017) A novel mathematical signal processing application which automates and improves the accuracy of FFR assessment. EUROPEAN HEART JOURNAL, Vol. 38 (pp 183-184) View this article in WRRO RIS download Bibtex download
  • Lungu A, Hose DR, Kiely DG, Capener D, Wild JM & Swift AJ (2017) Three Element Windkessel Model to Non-Invasively Assess PAH Patients: One Year Follow-up (pp 151-154) RIS download Bibtex download
  • Lungu A, Hose R, Capener D, Kiely D, Wild J & Swift A (2016) Response to treatment assessment in patients with PAH by MRI based computational modelling. 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases RIS download Bibtex download
  • Lungu A, Swift A, Capener D, Kiely D, Hose R & Wild J (2015) Diagnosis of pulmonary hypertension from MR image based computational models of pulmonary vascular haemodynamics and decision tree analysis. 4.3 Pulmonary Circulation and Pulmonary Vascular Disease RIS download Bibtex download
  • Morris P, Zwierzak I, Lawford P, Sir D, Hose R & Gunn J (2015) 209 The Development and Validation of anin silicoModel of Coronary Arterial Physiology for Diagnostic Use. Heart, Vol. 101(Suppl 4) (pp A115.1-A115) RIS download Bibtex download
  • Peters J, Lungu A, Weber FM, Waechter-Stehle I, Rodney Hose D & Weese J (2014) Comparison of CFD-Based and Bernoulli-Based Pressure Drop Estimates across the Aortic Valve Enabled by Shape-Constrained Deformable Segmentation of Cardiac CT Images (pp 211-219) RIS download Bibtex download
  • Lungu A, Wild J, Swift A, Capener D, Kiely D & Hose DR (2014) Automatic, Simultaneous, Non-invasive Measurements of Flow and Area in the Human Pulmonary Arteries from MRI Images (pp 259-264) RIS download Bibtex download
  • Morris PD, Ryan DR, Lycett R, Morton AC, Lawford PV, Hose DR & Gunn J (2012) COMPUTER MODELLED CORONARY PHYSIOLOGY AND "VIRTUAL" FRACTIONAL FLOW RESERVE FROM ROTATIONAL ANGIOGRAPHY. HEART, Vol. 98 (pp A14-A14) RIS download Bibtex download
  • Benkner S, Bisbal J, Engelbrecht G, Hose RD, Kaniovskyi Y, Koehler M, Pedrinaci C & Wood S (2012) Towards Collaborative Data Management in the VPH-Share Project (pp 54-63) RIS download Bibtex download
  • Cardenes R, Novikov A, Gunn J, Hose R & Frangi AF (2012) 3D reconstruction of coronary arteries from rotational X-ray angiography. Proceedings - International Symposium on Biomedical Imaging (pp 618-621) RIS download Bibtex download
  • Morris PD, Ryan DM, Lycett R, Morton AC, Lawford PV, Hose DR & Gunn JP (2011) Virtual Coronary Physiology and Anatomy Derived From Rotational Angiography: The First Step. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol. 58(20) (pp B189-B189) RIS download Bibtex download
  • Nallamothu RK, Li Y, Rafiroiu DR, Díaz-Zuccarini V, Narracott AJ, Lawford PV & Hose DR (2011) Multi-physics and Multi-scale Computational Evaluation of the Thrombogenic and Cavitational Potential of a Bileaflet Mechanical Heart Valve (pp 298-305) RIS download Bibtex download
  • Li Y, Nallamothu RK, Rafiroiu D, Iancu A, Díaz-Zuccarini V, Narracott AJ, Hose DR & Lawford PV (2011) CFD Analysis Study on the Impact of the Coronary Anatomy on the Efficiency of the Coronary Thrombectomy: The Effect of Bend Angles (pp 306-309) RIS download Bibtex download
  • Amatruda CM, Hose DR, Lawford PV & Narracott AJ (2011) Modelling the Development of In-Stent Restenosis: Preliminary Results of a Structural Model. INTERNATIONAL CONFERENCE ON ADVANCEMENTS OF MEDICINE AND HEALTH CARE THROUGH TECHNOLOGY, Vol. 36 (pp 276-279) RIS download Bibtex download
  • Hunter P, Coveney PV, de Bono B, Diaz V, Fenner J, Frangi AF, Harris P, Hose R, Kohl P, Lawford P , McCormack K et al (2010) A vision and strategy for the virtual physiological human in 2010 and beyond. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES, Vol. 368(1920) (pp 2595-2614) RIS download Bibtex download
  • Larrabide I, Cruz Villa-Urio M, Cardenes R, Pozo JM, Hose D & Frangi AF (2010) Automated intracranial aneurysm isolation and quantification.. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, Vol. 2010 (pp 2841-2844) RIS download Bibtex download
  • Larrabide I, Villa-Urio MC, Cardenes R, Pozo JM, Hose DR & Frangi AF (2010) Automated intracranial aneurysm isolation and quantification. 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 (pp 2841-2844) RIS download Bibtex download
  • Rafiroiu D, Munteanu M, Ciupa R, Munteanu R, Diaz V, Narracott AJ, Lawford PV & Hose DR (2009) EXPERIMENTAL STUDIES AND NUMERICAL SIMULATIONS OF SOME MECHANICAL HEART VALVES' BIOMECHANICS. MANAGEMENT OF TECHNOLOGICAL CHANGES, VOL 1 (pp 445-448) RIS download Bibtex download
  • Evans DJW, Caiazzo A, Falcone JL, Hegewald J, Lorenz E, Stahl B, Wang D, Bernsdorf J, Chopard B, Gunn J , Walker D et al (2009) COAST: Modelling Restenosis and Stent Based Therapies. INTERNATIONAL CONFERENCE ON ADVANCEMENTS OF MEDICINE AND HEALTH CARE THROUGH TECHNOLOGY, Vol. 26 (pp 319-322) RIS download Bibtex download
  • Barber DC, Hartwell J, Naylor S, Marzo A & Hose DR (2009) Determination of Wall Strain in Model Cerebral Aneurysms by Image Registration. INTERNATIONAL CONFERENCE ON ADVANCEMENTS OF MEDICINE AND HEALTH CARE THROUGH TECHNOLOGY, Vol. 26 (pp 283-286) RIS download Bibtex download
  • Turcu A, Lungu A, Vlad S, Rafiroiu D, Ciupa RV, Diaz VA, Narracott AJ, Lawford PV & Hose DR (2009) Closure Mechanics of Mechanical Heart Valve Prostheses - Experimental and Computational Analysis. INTERNATIONAL CONFERENCE ON ADVANCEMENTS OF MEDICINE AND HEALTH CARE THROUGH TECHNOLOGY, Vol. 26 (pp 363-368) RIS download Bibtex download
  • Caiazzo A, Evans D, Falcone J-L, Hegewald J, Lorenz E, Stahl B, Wang D, Bernsdorf J, Chopard B, Gunn J , Hose DR et al (2009) Towards a Complex Automata Multiscale Model of In-Stent Restenosis.. ICCS (1), Vol. 5544 (pp 705-714) RIS download Bibtex download
  • Bernsdorf J, Harrison SE, Smith SM, Lawford PV & Hose DR (2008) Applying the lattice Boltzmann technique to biofluids: A novel approach to simulate blood coagulation. COMPUTERS & MATHEMATICS WITH APPLICATIONS, Vol. 55(7) (pp 1408-1414) RIS download Bibtex download
  • Rajasekaran H, Lo Iacono L, Hasselmeyer P, Fingberg J, Summers P, Benkner S, Engelbrecht G, Arbona A, Chiarini A, Friedrich CM , Hofmann-Apitius M et al (2008) @neurIST - Towards a system architecture for advanced disease management through integration of heterogeneous data, computing, and complex processing services. Proceedings - IEEE Symposium on Computer-Based Medical Systems (pp 361-366) RIS download Bibtex download
  • Fenner J, Sucharov T, Hose DR, Jones I, Griffiths P & Wilkinson I (2008) The Karman Vortex in a Medical Imaging Context: A Validated Computational Model of Laminar Shedding.. MSV (pp 185-190) RIS download Bibtex download
  • Turcu AE, Rafiroiu DV, Diaz-Zuccarini V, Narracott AJ, Hose DR & Lawford PV (2008) Investigations of the thrombogenic and cavitational potentials of a bileaflet mechanical heart valve, using ANSYS-CFX. 2008 IEEE INTERNATIONAL CONFERENCE ON AUTOMATION, QUALITY AND TESTING, ROBOTICS (AQTR 2008), THETA 16TH EDITION, VOL III, PROCEEDINGS (pp 106-111) RIS download Bibtex download
  • Harrison SE, Bernsdorf J, Hose DR & Lawford PV (2007) Development of a lattice Boltzmann framework for numerical simulation of thrombosis. INTERNATIONAL JOURNAL OF MODERN PHYSICS C, Vol. 18(4) (pp 483-491) RIS download Bibtex download
  • Rafiroiu D, Díaz-Zuccarini V, Hose DR, Lawford PV, Narracott AJ & Ciupa RV (2007) The cavitational potential of a single-leaflet virtual MHV: A multi-physics and multiscale modelling approach. IFMBE Proceedings, Vol. 16(1) (pp 895-898) RIS download Bibtex download
  • Hammer SJ, Jeays A, Lee WT, Barber D, Hose R, Easson WJ & Hoskins PR (2007) A 3D ultrasound system for image guided modeling of patient-specific artery geometries. 2007 IEEE ULTRASONICS SYMPOSIUM PROCEEDINGS, VOLS 1-6 (pp 2469-2472) RIS download Bibtex download
  • Rafiroiu D, Diaz-Zuccarini V, Hose DR, Lawford PV, Narracott AJ & Ciupa RV (2007) The Cavitational Potential of a Single-leaflet Virtual MHV: A Multi-Physics and Multiscale Modelling Approach. 11TH MEDITERRANEAN CONFERENCE ON MEDICAL AND BIOLOGICAL ENGINEERING AND COMPUTING 2007, VOLS 1 AND 2, Vol. 16(1-2) (pp 895-898) RIS download Bibtex download
  • Diaz-Zuccanni V, Rafirou D, Hose DR, Lawford PV & Narracott AJ (2007) Multi-physics and multi-scale modelling in cardiovascular physiology: Advanced user methods for simulation of biological systems with ANSYS/CFX. Computational Science - ICCS 2007, Pt 1, Proceedings, Vol. 4487 (pp 794-801) RIS download Bibtex download
  • Clapworthy GJ, Kohl P, Gregerson H, Thomas SR, Viceconti M, Hose DR, Pinney D, Fenner J, McCormack K, Lawford P , Jan SVS et al (2007) Digital human modelling: A global vision and a European perspective. Digital Human Modeling, Vol. 4561 (pp 549-558) RIS download Bibtex download
  • Bernsdorf J, Harrison SE, Smith SM, Lawford PV & Hose DR (2006) Numerical simulation of clotting processes: A lattice Boltzmann application in medical physics. MATHEMATICS AND COMPUTERS IN SIMULATION, Vol. 72(2-6) (pp 89-92) RIS download Bibtex download
  • Jeays AD, Gillott R, Hose R, Lawford P, Jacob S, Spencer P & Bardham KD (2006) MRI studies of blood flow in the superior mesenteric artery (SMA). GASTROENTEROLOGY, Vol. 130(4) (pp A196-A196) RIS download Bibtex download
  • Gillott R, Jeays AD, Lawford PV, Jacob S, Bardhan KD, Hose DR & Spencer PA (2006) MRI studies of blood flow through the superior mesenteric artery. GUT, Vol. 55 (pp A114-A114) RIS download Bibtex download
  • Jeays A, Gillott R, Lawford P, Jacob S, Bardhan KD, Spencer PA & Hose R (2005) Gut blood flow: Modelling the dynamic anatomy of the superior mesenteric artery (SMA). GASTROENTEROLOGY, Vol. 128(4) (pp A656-A656) RIS download Bibtex download
  • Cirovic S, Bhola RM, Hose DR, Howard IC, Lawford PW & Parsons MA (2005) A computational study of the optic nerve evulsion. IUTAM Symposium on Impact Biomechanics: From Fundamental Insights to Applications, Vol. 124 (pp 469-476) RIS download Bibtex download
  • Bhola RM, Cirovic S, Parson MA, Hose DR, Lawford PV & Howard IC (2005) Modeling of the eye and orbit to simulate Shaken Baby syndrome. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Vol. 46 RIS download Bibtex download
  • Bernsdorf J, Harrison SE, Smith SM, Lawford PV & Hose DR (2005) Concurrent numerical simulation of flow and blood clotting using the lattice Boltzmann technique. 11th International Conference on Parallel and Distributed Systems Workshops, Vol II, Proceedings, (pp 336-340) RIS download Bibtex download
  • Castellano-Smith AD, Hartkens T, Schnabel JA, Hose R, Liu HY, Hall W, Truwit C, Hawkes DJ & Hill DLG (2002) A registration based mesh construction technique for finite element models of brains. MEDICAL IMAGING 2002: IMAGE PROCESSING, VOL 1-3, Vol. 4684 (pp 538-549) RIS download Bibtex download
  • Schnabel JA, Tanner C, Castellano-Smith AD, Degenhard A, Hayes C, Leach MO, Hose DR, Hill DLG & Hawkes DJ (2002) Validation of Nonrigid Registration of Contrast-Enhanced MR Mammography Using Finite Element Methods.. Bildverarbeitung für die Medizin, Vol. 56 (pp 143-146) RIS download Bibtex download
  • Schnabel JA, Tanner C, Castellano-Smith AD, Degenhard A, Hayes C, Leach MO, Hose DR, Hill DLG & Hawkes DJ (2002) Finite element based validation of non-rigid registration using single- and multi-level free-form deformations: Application to contrast-enhanced MR mammography. MEDICAL IMAGING 2002: IMAGE PROCESSING, VOL 1-3, Vol. 4684 (pp 550-561) RIS download Bibtex download
  • Tanner C, Degenhard A, Schnabel JA, Castellano-Smith AD, Hayes C, Sonoda LI, Leach MO, Hose DR, Hill DLG & Hawkes DJ (2002) Comparison of biomechanical breast models: a case study. MEDICAL IMAGING 2002: IMAGE PROCESSING, VOL 1-3, Vol. 4684 (pp 1807-1818) RIS download Bibtex download
  • Tanner C, Schnabel JA, Degenhard A, Castellano-Smith AD, Hayes C, Leach MO, Hose DR, Hill DLG & Hawkes DJ (2002) Validation of volume-preserving non-rigid registration: Application to contrast-enhanced MR-mammography. MEDICAL IMAGE COMPUTING AND COMPUTER-ASSISTED INTERVENTION-MICCAI 2002, PT 1, Vol. 2488 (pp 307-314) RIS download Bibtex download
  • Schnabel JA, Tanner C, Castellano-Smith AD, Leach MO, Hayes C, Degenhard A, Hose DR, Hill DLG & Hawkes DJ (2001) Validation of Non-rigid Registration Using Finite Element Methods.. IPMI, Vol. 2082 (pp 344-357) RIS download Bibtex download
  • Castellano-Smith AD, Hartkens T, Schnabel JA, Hose DR, Liu H, Hall WA, Truwit CL, Hawkes DJ & Hill DLG (2001) Constructing Patient Specific Models for Correcting Intraoperative Brain Deformation.. MICCAI, Vol. 2208 (pp 1091-1098) RIS download Bibtex download
  • Tanner C, Degenhard A, Schnabel JA, Smith AC, Hayes C, Sonoda LI, Leach MO, Hose DR, Hill DLG & Hawkes DJ (2001) A method for the comparison of biomechanical breast models. IEEE WORKSHOP ON MATHEMATICAL METHODS IN BIOMEDICAL IMAGE ANALYSIS, PROCEEDINGS (pp 11-18) RIS download Bibtex download
  • Noguchi Y, Marzouqa I, Hose DR, Paley MNJ, Wilkinson ID, Fenner JW & Griffiths PD (1999) Vortex shedding observations using magnetic resonance imaging, flow visualisation and computational fluid dynamics. COMPUTATIONAL METHODS AND EXPERIMENTAL MEASUREMENTS IX (pp 223-230) RIS download Bibtex download
  • Penrose JMT, Williams NW, Hose DR & Trowbridge EA (1998) Kinematic and stress analysis of metacarpophalangeal joint implants. COMPUTER METHODS IN BIOMECHANICS & BIOMEDICAL ENGINEERING - 2 (pp 439-446) RIS download Bibtex download
  • Penrose JMT, Hose DR & Trowbridge EA (1996) Cricket ball swing: A preliminary analysis using computational fluid dynamics. ENGINEERING OF SPORT (pp 11-19) RIS download Bibtex download

Reports

  • Carusi A (2015) In silico Clinical Trials: How Computer Simulations Will Transform the Biomedical Industry. An International Roadmap for an Industry-Driven Initiative. RIS download Bibtex download

Website content

  • Hose DR Home Page. RIS download Bibtex download