Professor Alireza Fazeli

PhD

Department of Oncology and Metabolism

Professor in Reproductive Medicine

a.fazeli@sheffield.ac.uk
+44 114 226 8345

Full contact details

Professor Alireza Fazeli
Department of Oncology and Metabolism
Level 4, JW408
Jessop Wing
Tree Root Walk
Sheffield
S10 2SF
Profile

I started my career as a Research Scientist at the Institute of Zoology, Zoological Society of London between 1996 and 2002. In 2002 I joined the Academic Unit of Reproductive and Developmental Medicine where I am a Professor of Reproductive and Developmental Medicine.

Research interests

I am interested in the cross-talk between gametes and embryos, and the maternal tract. Since the innate immune system plays a major role in this communication I am keen to understand how the innate immunity is involved in this maternal communication.

The Fazeli Research Group

Current projects:

  • Clinical significance of Toll-like receptors expression in the diagnosis of female infertility in Saudi-Arabia, 2013-2014,  Kingdom of Saudi Arabia National Guard Health Affairs, 84,706 EUR
  • Broodfish epigenetic models, 2013-2014, European Union Seventh Framework Programme (FP7): Infrastructures: Aquaculture infrastructures for excellence in European fish research, (AQUAEXCEL), 40,000 EUR
  • Epigenetics and periconception environment, 2012-2016, European Cooperation in Science and Technology (COST), 1,000,000 EUR
Publications

Books

  • Izquierdo M, Otero-Ferrer F, Fair T, Gutierrez-Adan A, Fazeli A & Van Soom A (2014) Proceedings of the Epiconcept Workshop 2014, 07-09 May 2014. Las Palmas, Spain: Epiconcept COST Action FA1201. RIS download Bibtex download
  • Fazeli A & Gomez E (2011) Proceedings of the 4th General Meeting of GEMINI, 29 September - 2 October 2011. Gijon, Spain: GEMINI COST Action FA0702. RIS download Bibtex download
  • Fazeli A & Van Soom A (2010) Theriogenology: Proceedings of the GEMINI Research Workshop, Lansk, Poland, 7-9 May 2009. Elsevier. RIS download Bibtex download
  • Fazeli A, Gandolfi F & Ledda S (2009) Proceedings of the 2nd General Meeting of GEMINI, 1-3 October 2009. Sardini, Italy: GEMINI. RIS download Bibtex download
  • Fazeli A (1996) Clinical and physiological aspects of sperm zona pellucida interaction. Utrecht: Addix Wijk bij Duurstede. RIS download Bibtex download

Edited books

  • Soom A, Fazeli A & Engrola S (Eds.) (2014) Proceedings of the Epiconcept Conference 2014, 01-03 October 2014. Vilamoura, Portugal: Epiconcept COST Action FA1201. RIS download Bibtex download
  • Van Soom A, Fazeli A, Tandler A & Piferrer F (Eds.) (2013) Proceedings of the Epiconcept Workshop 2013, 13-16 October 2013. Sant Feliu de Guixols, Spain: Epiconcept COST Action FA1201. RIS download Bibtex download
  • Van Soom A, Fazeli A & Kuran M (Eds.) (2013) Proceedings of the Epiconcept Conference 2013, 24-25 April 2013. Antalya, Turkey: Epiconcept COST Action FA1201. RIS download Bibtex download

Journal articles

Chapters

Conference proceedings papers

  • Lättekivi F, Reimann E, Keermann M, Abram K, Kõks S, Kingo K & Fazeli A (2017) Multicomponent biomarkers : a novel method for accurate diagnosis of psoriasis. British Journal of Dermatology, Vol. 177(5) (pp E294-E295). London, UK, 30 November 2017 - 2 December 2017. View this article in WRRO RIS download Bibtex download
  • Soom AV & Fazeli A (2017) COST-Action GEMINI and EPICONCEPT: what we learned after 8 years?. Animal Reproduction, Vol. 14(3) (pp 630-634) RIS download Bibtex download
  • Amjadi F, Salehi E, Mehdizadeh M, Ashrafi M, Aflatoonian A, Fazeli A & Aflatoonian R (2016) Localization of toll like receptors (TLRs) in human fallopian tube epithelial cells. HUMAN REPRODUCTION, Vol. 31 (pp 317-317) RIS download Bibtex download
  • Fazeli A (2015) Enhancement of Animal Production by Foetal Imprintings/Epigenetics. REPRODUCTION IN DOMESTIC ANIMALS, Vol. 50 (pp 27-28) RIS download Bibtex download
  • Nafee T, Sanchez-Lopez JA, Heath PR, Ola B & Fazeli A (2015) The role of microRNAs in mediating a state of enhanced endometrial receptivity in response to trophoblast cells: an integrative analysis. HUMAN REPRODUCTION, Vol. 30 (pp 106-106) RIS download Bibtex download
  • Otero-Ferrer F, Negrin D, Zamorano MJ, Izquierdo M, Molina L, Fazeli A & Holt WV (2014) Can periconception diet affect seahorse male reproductive success?. Aquaculture Europe 14. San Sebastian, Spain, 14-17 October 2014 RIS download Bibtex download
  • Sanchez-Lopez JA, Carmel I, Nafee T, Heifetz Y & Fazeli A (2014) Designing molecular beacons for microRNA detection in the periconceptional environment. Epigenetics and Periconception Environment, 01-03 October 2014. Vilamoura, Portugal RIS download Bibtex download
  • Fazeli A (2014) Our changing view of the periconceptional environment: its importance and regulation. 26th Congress of the Polish Physiological Society, Vol. 65 (pp 64-64). Szczecin, Poland RIS download Bibtex download
  • Basatvat S & Fazeli A (2013) Characterisation of Tribbles-2 modulation of TLR5 signalling pathway. 3rd Symposium of the Academic Unit of Reproductive and Developmental Medicine, University of Sheffie (pp 15-15). Sheffield, United Kingdom RIS download Bibtex download
  • Montazeri M & Fazeli A (2013) Understanding the potential mechanisms involved in TLR3 induced implantation failure using an in vitro human implantation model. 3rd Symposium of the Academic Unit of Reproductive and Developmental Medicine, University of Sheffie (pp 16-16). Sheffield, United Kingdom RIS download Bibtex download
  • Nafee T & Fazeli A (2013) The developing pig embryo modulates the microRNA expression profile of the endometrium. 3rd Symposium of the Academic Unit of Reproductive and Developmental Medicine, University of Sheffie (pp 17-17). Sheffield, United Kingdom RIS download Bibtex download
  • Alminana C, Vazquez JM, Roca J, Martinez E & Fazeli A (2013) The dynamic uterine environment: meeting the immune and metabolic demands of the early pig embryo. Epiconcept Conference 2013, 24-25 April 2013 (pp 69-69). Antalya, Turkey RIS download Bibtex download
  • Otero F, Izquierdo M, Segade A, Fazeli A & Holt A (2013) Seahorses: A new and unique epigenetic model. Epiconcept Workshop 2013, 13-16 October 2013 (pp 59-59). Sant Feliu de Guixols, Spain RIS download Bibtex download
  • Nafee T, Sanchez-Lopez J, Heath P, Alminana C, Roca J, Martinez E, Skull J, Li TC & Fazeli A (2013) The developing pig embryo modulates the microRNA expression profile of the endometrium. Epiconcept Workshop 2013, 13-16 October 2013 (pp 46-46). Sant Feliu de Guixols, Spain RIS download Bibtex download
  • Caballero I, Basatvat B, Sanchez-Lopez J, Montazeri M, Maslehat N, Elliott S & Fazeli A (2013) Estradiol modulates Toll-like receptor 5-mediated AP-1 transcriptional activity. Epiconcept Conference 2013, 24-25 April 2013 (pp 61-61). Antalya, Turkey RIS download Bibtex download
  • Alminana C, Caballero IC, Cuello C, Parrilla I, Gil MA, Gomis J, Angel MA, Sanchez-Osorio J, Del Olmo D, Vazquez JM , Vazquez JL et al (2013) The pig uterus distinguishes between vitrified and fresh embryos. 17th Conference of the European Society for Domestic Animal Reproduction, ESDAR, 12-14 September 201. Bologna, Italy RIS download Bibtex download
  • Sanchez-Lopez J & Fazeli A (2013) Activation of uterine innate immune system affects embryo implantation and endometrial receptivity. 3rd Symposium of the Academic Unit of Reproductive and Developmental Medicine, University of Sheffie (pp 7-7). Sheffield, United Kingdom RIS download Bibtex download
  • Montazeri M, Sanchez-Lopez J, Maslehat N, Caballero I, Elliott S & Fazeli A (2013) Understanding the potential mechanisms involved in implantation failure induced by TLR3 activation in vitro. Epiconcept Conference 2013, 24-25 April 2013 (pp 121-121). Antalya, Turkey RIS download Bibtex download
  • Basatvat B, Caballero I, Elliott S & Fazeli A (2013) Estradiol decreases NF-kappa B activation through GPR30 and ER alpha. Epiconcept Conference 2013, 24-25 April 2013 (pp 120-120). Antalya, Turkey RIS download Bibtex download
  • Basatvat S, Elliott S & Fazeli A (2012) Estradiol decrease NF-ĸB activation through GPR30 and ER alpha. 2nd Symposium of the Academic Unit of Reproductive and Developmental Medicine, University of Sheffie. Sheffield, United Kingdom RIS download Bibtex download
  • Montazeri M, Sanchez-Lopez J, Maslehat N, Caballero-Posadas I, Elliott S & Fazeli A (2012) Understanding the potential mechanisms involved in implantation failure induced by TLR3 activation in vitro. 2nd Symposium of the Academic Unit of Reproductive and Developmental Medicine, University of Sheffie. Sheffield, United Kingdom RIS download Bibtex download
  • Sanchez-Lopez J, Montazeri M, Maslehat N, Caballero-Posadas I, Elliott S, Hobbs J & Fazeli A (2012) Nano-scale membrane alterations are induced by the activation of TLR 2 and 2/6 in endometrial epithelial cells. 2nd Symposium of the Academic Unit of Reproductive and Developmental Medicine, University of Sheffie. Sheffield, United Kingdom RIS download Bibtex download
  • Dell Valle I, Fazeli A & Holt W (2012) Effect of Heat Shock Protein HSPA8 on bull sperm cryopreservation. 2nd Symposium of the Academic Unit of Reproductive and Developmental Medicine, University of Sheffie. Sheffield, United Kingdom RIS download Bibtex download
  • Maslehat N, Sanchez-Lopez J, Montazeri M, Caballero-Posadas I, Elliott S & Fazeli A (2012) Understanding the TLR9 intracellular signalling pathway involved in mediating the reduction of trophoblast cells binding to epithelial cells in vitro. 2nd Symposium of the Academic Unit of Reproductive and Developmental Medicine, University of Sheffie. Sheffield, United Kingdom RIS download Bibtex download
  • Fazeli A (2012) Embryo-maternal communication. 28th Scientific Meeting of the European Embryo Transfer Association, 07-08 September 2012. Saint Malo, France RIS download Bibtex download
  • Moein-Vaziri N, Holt WV, Pockley AG & Fazeli A (2012) Exogenous HSPA8 increases sperm viability via a cholesterol-dependent membrane interactions mechanism. Annual Meeting of the British Andrology Society: Testicular dysfunction and the infertile patient, 1. University of Bradford, Bradford, United Kingdom RIS download Bibtex download
  • Maslehat N, Sanchez-Lopez J, Montazeri M, Caballero-Posadas I, Elliott S & Fazeli A (2012) Toll-like receptor 9 activation reduces trophoblast cells binding to endometrial cells in vitro. Medical School Annual Research Meeting 2012, 11-12 June 2012 (pp 54-54). University of Sheffield, Sheffield, United Kingdom RIS download Bibtex download
  • Montazeri M, Sanchez-Lopez J, Maslehat N, Elliott S, Caballero-Posadas I & Fazeli A (2012) Toll-like receptor 3 activation reduces trophoblast cells binding to endometrial cells in human. Medical School Annual Research Meeting 2012, 11-12 June 2012 (pp 49-49). University of Sheffield, Sheffield, United Kingdom RIS download Bibtex download
  • Burkitt M, Walker D, Romano DM & Fazeli A (2011) Modelling sperm behaviour in a 3D environment. Proceedings of the 9th International Conference on Computational Methods in Systems Biology, CMSB'11 (pp 141-149). Paris, France, 21 September 2011 - 23 September 2011. RIS download Bibtex download
  • Burkitt M, Romano DM, Walker DC & Fazeli A (2010) 3D Modelling of Complex Biological Structures: The Oviduct.. TPCG (pp 255-262) RIS download Bibtex download
  • Burkitt M, Romano DM, Walker D & Fazeli A (2010) Using computational systems biology to investigate sperm navigation and transport in the female reproductive tract. Systems Biology in Maternal Communication with Gametes and Embryo. Opatija, Croatia, 9 May 2010 - 13 May 2010. RIS download Bibtex download
  • Aboussahoud W, Bruce C, Elliott S & Fazeli A (2010) Activation of Toll-like receptor 5 decreases attachment of human trophoblast cells to endometrial cells. University of Sheffield Medical School Research Meeting 5-6 July 2010. Sheffield, United Kingdom RIS download Bibtex download
  • Burkitt M, Walker D, Romano DM & Fazeli A (2010) Using the GPU and multi-core CPU to generate a 3D oviduct through feature extraction from histology slides. Proceedings of the 9th Int. Workshop on Parallel and Distributed Methods in Verification, PDMC 2010 - Joint with the 2nd Int. Workshop on High Performance Computational Systems Biology, HiBi 2010 (pp 78-87) RIS download Bibtex download
  • Aflatoonian B, Aflatoonian R, Ruban L, Fazeli A & Moore HD (2009) Embryoid bodies from human embryonic stem cells form a niche for male germ cell development in vitro. PAPERS CONTRIBUTED TO THE 9TH INTERNATIONAL CONGRESS OF ANDROLOGY. (pp 169-174). Barcelona, Spain, 7 March 2009 - 10 March 2009. RIS download Bibtex download
  • Fazeli A, Burkitt M, Walker D & Romano DM (2009) The Virtual Oviduct: An Essential Tool for the Application of Computational Biology Approaches to Investigation of Maternal Interaction with Gametes and Embryo. BIOLOGY OF REPRODUCTION (pp 115-115) RIS download Bibtex download
  • Aflatoonian R, Lee KF, Yeung WSB, Tsao SW & Fazeli A (2008) Innate immunity is influence by sex hormones in fallopian tube. REPRODUCTION IN DOMESTIC ANIMALS, Vol. 43 (pp 66-66) RIS download Bibtex download
  • Aflatoonian R, Ward J, Lee K-F, Yeung W, Tsao SW, Elliott S & Fazeli A (2008) Sex hormones enhance TLR3 response to its specific ligand in human Fallopian tube epithelial cells. BIOLOGY OF REPRODUCTION (pp 197-197) RIS download Bibtex download
  • Aflatoonian R, Tuckerman E, Elliott SL, Bruce C, Aflatoonian A, Li TC & Fazeli A (2006) Expression of toll-like receptors in endometrium during the menstrual cycle. JOURNAL OF REPRODUCTIVE IMMUNOLOGY, Vol. 71(2) (pp 152-152) RIS download Bibtex download
  • Holt WV, Elliott RM, Fazeli A, Sostaric E, Georgiou AS, Satake N, Prathalingam N & Watson PF (2006) Harnessing the biology of the oviduct for the benefit of artificial insemination.. Society of Reproduction and Fertility supplement, Vol. 62 (pp 247-259) RIS download Bibtex download
  • Sostaric E, Georgiou AS, Aflatoonian R, Pewsey E, Wong CH, Moore HDM, Watson PF, Holt WV & Fazeli A (2005) Profiling porcine oviductal epithelial cell surface membrane proteins.. BIOLOGY OF REPRODUCTION (pp 202-202). Lodi, Italy, 20 February 2006 - 21 February 2006. RIS download Bibtex download
  • Georgiou AS, Wong CH, Moore HD & Fazeli A (2004) Boar spermatozoa alter the oviductal secretory proteome.. BIOLOGY OF REPRODUCTION (pp 221-222) RIS download Bibtex download
  • Elliott RMA, Duncan A, Watson PF, Holt WV & Fazeli A (2001) Peripheral bound membrane proteins are involved in the maintenance of boar sperm viability by oviductal apical plasma membrane preparations in vitro. MOL BIOL CELL, Vol. 12 (pp 117A-117A) RIS download Bibtex download
  • Fazeli A, Watson PF & Holt WV (2000) Isthmic apical plasma membrane preparations maintain boar sperm viability in vitro in a dose dependent manner.. BIOL REPROD, Vol. 62 (pp 259-259) RIS download Bibtex download
  • Fazeli A, Moore A & Holt WV (2000) British Andrology Society Workshop: Sperm interactions with epithelia and their products. Human Fertility, Vol. 3(3) (pp 166-171) RIS download Bibtex download
  • Aboussahoud W, Aflatoonian R, Bruce C, Elliot S & Fazeli A () The influence of steroidal sex hormones on the expression of TLR5 in different human endometrial cell lines. Infection, Inflammation and Immunity Research Day, University of Sheffield. Sheffield, United Kingdom, 11 January 2008. RIS download Bibtex download
  • Elliott RMA, Satake N, Watson PF, Fazeli A & Holt WV () Porcine sperm-head receptor interaction with proteins peripherally bound to the oviductal lumen. Reproduction Fertility and Development. Copenhagen, Denmark, 8 January 2005 - 12 January 2005. RIS download Bibtex download
  • Sostaric E, Georgiou AS, Wong CH, Moore HDM, Watson PF, Holt WV & Fazeli A () Profiling porcine oviductal epithelial cell surface membrane proteins. 38th Annual Meeting of the Society for the Study of Reproduction. Quebec City, Canada, 24 July 2005 - 27 July 2005. RIS download Bibtex download
  • Staves J, Pewsey E, Bruce C, Georgiou AS, Elliott S, Seytanoglu A & Fazeli A () Intracellular proteomic analysis of embryonic carcinoma cells. Infection, Inflammation and Immunity Research Day, University of Sheffield. Sheffield, United Kingdom, 11 January 2008. RIS download Bibtex download
  • Fazeli A, Underwood CM, Narracott AJ, Walker D, Burkitt M, Romano DM & Lawford PV () Analysis of oviduct flow based on histological data. 17th Congress of the European Society of Biomechanics. University of Edinburgh, Edinburgh, United Kingdom, 5 July 2010 - 8 July 2010. RIS download Bibtex download
  • Sostaric E, Georgiou A, Wong CH, Aflatoonian R, Pewsey E, Moore HDM, Watson PF, Holt WV & Fazeli A () Identification and characterization of the oviductal epithelial cell surface proteome. Expanding Proteomics: New Directions in Biology, Chemistry, Pharmaceutical Sciences and Medicine, An. Zurich, Switzerland, 5 December 2005 - 7 December 2005. RIS download Bibtex download
  • Sostaric E, Georgiou AS, Elliott RMA, Moore HDM, Watson PF, Holt WV & Fazeli A () Global profiling of the oviductal epithelial cells plasma membrane surface proteins. Human Fertility. Warwick, United Kingdom, 2 April 2005 - 6 April 2005. RIS download Bibtex download
  • Shadan S, Fazeli A, Duncan A, Watson PF & Holt WV () The effect of apical plasma membrane fractions of porcine oviduct on boar sperm capacitation. Journal of Reproduction and Fertility Abstract Series. Warwick, United Kingdom, December 1999. RIS download Bibtex download
  • Sharifi M, Akmali V, Fazeli A & Holt W () Postnatal growth in four Pipistrllus kuhli reared in a flight cage. 13th International Bat Research Conference. Mikołajki, Poland, 23 August 2004 - 27 August 2004. RIS download Bibtex download
  • Bruce C, Georgiou AS, Pewsey E, Jones M, Baker D, Ow SY, Wright PC, Freberg C, Collas P & Fazeli A () The proteomic profile of cells reprogrammed using human embryonic carcinoma cell extracts. 6th Annual Meeting of the International Society for Stem Cell Research. Philadelphia, United States, 11 June 2008 - 14 June 2008. RIS download Bibtex download
  • Pewsey E, Bruce C, Georgiou AS, Jones M, Baker D, Ow SY, Wright PC, Freberg CK, Collas P & Fazeli A () The proteomic profile of cells reprogrammed using human embryonic carcinoma cell extracts. Medical School Research Day, University of Sheffield. Sheffield, United Kingdom, 9 June 2008 - 10 June 2008. RIS download Bibtex download
  • Sanchez-Lopez J, Montazeri M, Maslehat N, Elliott S, Caballero-Posadas I & Fazeli A () The activation of the endometrial TLR-2 affect human trophoblast cells binding to endometrial cells in vitro. Periconceptional Developmental Programming, GEMINI COST Action FA0702. Jerusalem, Israel, 31 May 2011 - 3 June 2011. RIS download Bibtex download
  • Pewsey E, Bruce C, Georgiou AS, Baker D, Ow SY, Wright PC, Freberg CK, Collas P & Fazeli A () Nuclear reprogramming: exploring the proteome. 3rd United Kingdom Stem Cell Meeting: Epigenetics and Differentiation. Regents College, London, United Kingdom, 11 March 2008. RIS download Bibtex download
  • Fazeli A, Pewsey E, Bruce C, Georgiou AS, Jones M, Baker D, Collas P & Andrews PW () The characterisation of cell surface markers in cells reprogrammed using cellular extracts. Medical School Research Day, University of Sheffield. Sheffield, United Kingdom, 19 June 2007. RIS download Bibtex download
  • Pewsey E, Bruce C, Georgiou AS, Baker D, Ow SY, Wright PC, Freberg C, Collas P, Andrews PW & Fazeli A () Characterisation of the proteomic profile of cells reprogrammed using embryonic carcinoma cell extracts. Integrative Proteomics: Structure, Function, and Interaction. 3rd Joint Meeting of the British Socie. Cambridge, United Kingdom, 12 July 2006 - 14 July 2006. RIS download Bibtex download
  • Parlevliet JM, De Loos F, Fazeli A, Bevers MM, Vos PLAM, Pieterse M, Taverne M & Colenbrander B () Transvaginal ultrasound guided ovum pick-up in the horse, recovery rate and oocyte quality. Journal of Reproduction and Fertility Abstract Series. Aachen, Germany, December 1993. RIS download Bibtex download
  • Fazeli A, Parlevliet JM, Steenweg W, Bevers MM & Colenbrander B () The effect of storage methods on the sperm zona binding in the horse. Society for the Study of Reproduction. Caxambu, Brazil, 7 August 1994 - 13 August 1994. RIS download Bibtex download
  • Pewsey E, Bruce C, Georgiou AS, Aflatoonian R, Andrews PW & Fazeli A () Somatic cell nuclear reprogramming using Xenopus laevis oocyte extract. Medical School Research Day, University of Sheffield. Sheffield, United Kingdom, 12 June 2006 - 13 June 2006. RIS download Bibtex download
  • Montazeri M, Sanchez-Lopez J, Maslehat N, Elliott S, Caballero-Posadas I & Fazeli A () Toll-like receptor 3 activation reduces trophoblast cells binding to endometrial cells in human. 4th General Meeting of Maternal Interaction with Gametes and Embryos, GEMINI Cost Action FA0702. Gijon, Spain, 29 September 2011 - 2 October 2011. RIS download Bibtex download
  • O'Brien NL, Fazeli A, Duncan A, Watson PF & Holt WV () Porcine oviductal epithelial cells obtained from prepubertal gilt oviducts can induce boar sperm capacitation in vitro. Journal of Reproduction and Fertility Abstract Series. University of Birmingham, Birmingham, United Kingdom, 13 November 1998 - 14 November 1998. RIS download Bibtex download
  • Monkkonen KS, Aflatoonian R, Laitinen JT, Tuckerman E, Li TC & Fazeli A () Hormonal regulation of Gαi2 and mPRa in a human Fallopian tube epithelial cell line. Medical School Research Day, University of Sheffield. Sheffield, United Kingdom, 19 June 2007. RIS download Bibtex download
  • Monkkonen KS, Aflatoonian R, Lee KF, Yeung WSB, Tsao SW, Laitinen JT, Tuckerman E, Li TC & Fazeli A () Localization and variable expression of Gai2 in human endometrium and Fallopian tubes. 2nd International Student Award and Congress in Reproductive Medicine. Yazd, Iran, 11 May 2007 - 13 May 2007. RIS download Bibtex download
  • Moein-Vaziri N, Elliott S, Pockley AG & Fazeli A () Effect of HSPA8 on boar sperm viability. 31st Annual Meeting of the British Andrology Society. Belfast, United Kingdom, 19 January 2009 - 20 January 2009. RIS download Bibtex download
  • Monkkonen KS, Aflatoonian R, Laitinen JT, Tuckerman E, Li TC & Fazeli A () Localization and variable expression of Gαi2 in human reproductive tissues. Human Embryonic Stem Cells - Progress Towards Cell Medicine, International Symposium, University of . Sheffield, United Kingdom, 14 July 2006. RIS download Bibtex download
  • Moein-Vaziri N, Alminana C, Jones R, Aghamohammadzadeh S, Pockley AG & Fazeli A () Effect of extracellular HSPA8 on boar sperm membrane fluidity. Meeting of Maternal Interaction with Gametes and Embryos, GEMINI Cost Action FA0702. Soustons, France, 1 October 2010 - 2 October 2010. RIS download Bibtex download
  • Moein-Vaziri N, Alminana C, Jones R, Aghamohammadzadeh S, Pockley G & Fazeli A () The effect of extracellular HSPA8 on boar sperm membrane fluidity and its relation to capacitation. 32nd Annual Meeting of the British Andrology Society. Alderley Park, United Kingdom, 9 November 2010 - 10 November 2010. RIS download Bibtex download
  • Ibrahim W, Alminana C & Fazeli A () Toll-like receptors and pregnancy: embryo(s) as modulators of innate immune response. 4th General Meeting of Maternal Interaction with Gametes and Embryos, GEMINI Cost Action FA0702. Gijon, Spain, 29 September 2011 - 2 October 2011. RIS download Bibtex download
  • Martinez C, Caroline E, Martinez C, Gil MA, Parrilla I, Cuello C, Sanchez-Osorio J, Vazquez JL, Vazquez JM, Roca J , Martinez E et al () Embryo alters uterine proteomic profile. 4th General Meeting of Maternal Interaction with Gametes and Embryos, GEMINI Cost Action FA0702. Gijon, Spain, 29 September 2011 - 2 October 2011. RIS download Bibtex download
  • Maslehat N, Sanchez-Lopez J, Montazeri M, Caballero-Posadas I & Fazeli A () Toll-like receptor 9 activation inhibits trophoblast cells binding to endometrial cells in vitro. 4th General Meeting of Maternal Interaction with Gametes and Embryos, GEMINI Cost Action FA0702. Gijon, Spain, 29 September 2011 - 2 October 2011. RIS download Bibtex download
  • Moein-Vaziri N, Alminana C, Jones R, Aghamohammadzadeh S, Pockley AG & Fazeli A () Influence of extracellular HSPA8 (HSC70) on boar sperm viability and membrane fluidity. Heat Shock Proteins in Cancer and Immunology. Woods Hole, MA, United States, 7 November 2010 - 11 November 2010. RIS download Bibtex download
  • Green CE, Holt WV, Watson PF & Fazeli A () Lactose specifically inhibits sperm binding to porcine isthmic oviductal epithelial cells in vitro. Journal of Reproduction and Fertility Abstract Series. Edinburgh, United Kingdom, 31 July 2000 - 2 August 2000. RIS download Bibtex download
  • Holt C, Fazeli A, Moore HDM, Bevers MM, Holt WV & Colenbrander B () Acrosomal status of boar semen bound to homologous hemi-zona determined by fluorescent staining. Journal of Reproduction and Fertility Abstract Series. Aachen, Germany, December 1993. RIS download Bibtex download
  • Georgiou AS, Sostaric E, Wong CH, Snijders APL, Wright PC, Vazquez JM, Roca J, Martinez EA, Moore HD & Fazeli A () Gametes alter the oviductal secretory proteome in vivo. 36th Annual Conference of the Society for Reproductive Biology. Perth, Australia, 4 September 2005 - 7 September 2005. RIS download Bibtex download
  • Georgiou AS, Wong CH, Snijders B, Wright PC, Moore HD, Fazeli A & Aflatoonian B () Spermatozoa alter oviductal secretory proteome. Human Fertility. Warwick, United Kingdom, 2 April 2005 - 6 April 2005. RIS download Bibtex download
  • Moeinvaziri N, Gil MA, Maside C, Parrilla I, Alminana C, Roca J, Vazques JM, Martinez E, Pockley AG & Fazeli A () Brief exposure of spermatozoa to HSPA8 enhances fertilisation and monospermy in a porcine in vitro fertilisation system. 4th General Meeting of Maternal Interaction with Gametes and Embryos, GEMINI Cost Action FA0702. Gijon, Spain, 29 September 2011 - 2 October 2011. RIS download Bibtex download
  • Georgiou AS, Sostaric E, Snijders APL, Wright PC & Fazeli A () Cell surface protein trafficking in oviductal cells in response to spermatozoa. 7th Siena Meeting from Genome to Proteome: Back to the Future. Siena, Italy, 3 September 2006 - 7 September 2006. RIS download Bibtex download
  • Georgiou AS, Sostaric E, Snijders APL, Wright PC & Fazeli A () A global quantitative profiling technology to investigate cell surface protein trafficking. Integrative Proteomics: Structure, Function, and Interaction. 3rd Joint Meeting of the British Socie. Cambridge, United Kingdom, 12 July 2006 - 14 July 2006. RIS download Bibtex download
  • Fazeli A, Steenweg W, Bevers MM, De Loos FAM & Colenbrander B () The development of a hemi-zona assay for porcine sperm. 12th International Congress on Animal Reproduction. The Hague, The Netherlands, 23 August 1992 - 27 August 1992. RIS download Bibtex download
  • Fazeli A, Watson PF & Holt WV () Assessment of a porcine sperm-oviduct culture system using frozen-thawed oviductal cells. Journal of Reproduction and Fertility Abstract Series. York, United Kingdom, July 1997. RIS download Bibtex download
  • Gan CS, Burja AM, Fazeli A, Reardon KF & Wright PC () Transcriptome and proteome dynamics of Synecocystis sp. PCC 6803 during light-dark cycling. Integrative Proteomics: Structure, Function, and Interaction. 3rd Joint Meeting of the British Socie. Cambridge, United Kingdom, 12 July 2006 - 14 July 2006. RIS download Bibtex download
  • Fazeli A, Steenweg W, Bevers MM & Colenbrander B () Sperm-zona binding in the bovine is not influenced by the day to day variations in ejaculates. Journal of Reproduction and Fertility Abstract Series. Aachen, Germany, 16 December 1992 - 16 December 1992. RIS download Bibtex download
  • Fazeli A, Steenweg W, Bevers MM, De Loos FAM & Colenbrander B () Sperm-zona binding; an additional parameter to assess quality of bull semen. Journal of Reproduction and Fertility Abstract Series. Paris, France, 13 December 1991 - 14 December 1991. RIS download Bibtex download
  • Fazeli A, Georgiou AS, Sostaric E, Wong C, Watson PF & Holt WV () Female reproductive tract has a sperm recognition system. Human Fertility. Warwick, United Kingdom, 2 April 2005 - 6 April 2005. RIS download Bibtex download
  • Fazeli A () Fertility-related proteins in oviduct: HSPA8, a brief history. 23rd annual Meeting of the AI-Vets. Prague, Czech Rebuplic, 19 October 2011 - 21 October 2011. RIS download Bibtex download
  • Fazeli A () Maternal communication with gametes and embryo; from in vivo to in silico. 7th International Conference on Boar Semen Preservation. Bonn, Germany, 14 August 2011 - 17 August 2011. RIS download Bibtex download
  • Fazeli A, Duncan A, Watson PF & Holt WV () Preferential binding of uncapacitated boar spermatozoa to porcine oviductal epithelial cells in vitro. 8th International Symposium on Spermatology. Montreal, Canada, 17 August 1998 - 22 August 1998. RIS download Bibtex download
  • Fazeli A () The sperm zona pellucida binding assays: capacitation, the acrosome reaction and sperm function assessment methods. British Andrology Society Workshop, 1993. RIS download Bibtex download
  • Fazeli A () Transcriptome alteration in mouse oviduct 6 hours after mating. Gordon Research Conferences: Reproductive Tract Biology. New London, Connecticut, United States, 30 June 2002 - 5 July 2002. RIS download Bibtex download
  • Chong SPK, Burja AM, Radianingtyas H, Fazeli A & Wright PC () Alcohol and ketone metabolisms of Sulfolobus solfataricus. Integrative Proteomics: Structure, Function, and Interaction. 3rd Joint Meeting of the British Socie. Cambridge, United Kingdom, 12 July 2006 - 14 July 2006. RIS download Bibtex download
  • Elliott RMA, Watson PF, Holt WV, Hudson-Davies R & Fazeli A () Non-glycosylated peripheral proteins of the sow oviduct are involved in the maintenance of boar sperm viability in vitro. Journal of Reproduction and Fertility Abstract Series. Aberdeen, United Kingdom, 13 July 2003 - 17 July 2003. RIS download Bibtex download
  • Burkitt M, Walker D, Romano DM & Fazeli A () Using computational modelling to understand sperm transport and navigation in the female reproductive tract. 32nd Annual Meeting British Andrology Society. AstraZeneca Pharmaceuticals, Alderley Park, United Kingdom, 9 November 2010 - 10 November 2010. RIS download Bibtex download
  • Cheng FP, Tremoleda JL, Fazeli A, Pycock JF, Bevers MM & Colenbrander B () Induction of true acrosome reaction in stallion spermatozoa by preovulatory follicle fluid aspirated from oestrus mares. 2nd International Symposium on Stallion Semen. Amersfoort, The Netherlands, 7 March 1996 - 8 March 1996. RIS download Bibtex download
  • Burkitt M, Romano DM, Walker D & Fazeli A () Computational modelling of sperm movements within the oviduct. 4th General Meeting of Maternal Interaction with Gametes and Embryos, GEMINI Cost Action FA0702. Gijon, Spain, 29 September 2011 - 2 October 2011. RIS download Bibtex download
  • Borg K, Malmgren L, Colenbrander B, Fazeli A & Parlevliet J () Influence of thawing method on motility, plasma membrane integrity and morphology of frozen-thawed stallion spermatozoa. 2nd International Symposium on Stallion Semen. Amersfoort, The Netherlands, 7 March 1996 - 8 March 1996. RIS download Bibtex download
  • Bracher V, Ousey JC, Fazeli A, Murgatroyd P & Rossdale PD () Hydrogen breath test in foals. 6th International Symposium on Equine Reproduction. Caxambu, Brazil, 7 August 1994 - 13 August 1994. RIS download Bibtex download
  • Burkitt M, Romano DM, Walker D & Fazeli A () Procedural reconstruction of a three dimensional graphical model of an oviduct. 1st General Meeting of Maternal Interaction with Gametes and Embryos, GEMINI Cost Action FA0702. Volos, Greece, 9 October 2008 - 11 October 2008. RIS download Bibtex download
  • Basatvat S, Elliot S, Caballero-Posadas I, Sanchez-Lopez J, Maslehat N, Montazeri M & Fazeli A () Sex-hormones influence TLR5 responses to flagellin. 4th General Meeting of Maternal Interaction with Gametes and Embryos, GEMINI Cost Action FA0702. Gijon, Spain, 29 September 2011 - 2 October 2011. RIS download Bibtex download
  • Blase N, Dostalova Z, Kochel C, Fazeli A & Töpfer-Petersen E () Isolation and characterization of tryptic peptides of fetuin and porcine zona pellucida and investigation of their possible physiological function in sperm-egg interaction. Annual Conference of Physiology and Pathology of Reproduction. Leipzig, Germany, 1995. RIS download Bibtex download
  • Alminana C, Heath P, Aldarmahi A, Vazquez JM, Roca J, Martinez EA & Fazeli A () Embryos elicit a local response in the maternal tract. Medical School Research Meeting, University of Sheffield. Sheffield, United Kingdom, 5 July 2010 - 6 July 2010. RIS download Bibtex download
  • Alminana C, Heath P, Aldarmahi A, Vazquez JM, Roca J, Martinez EA & Fazeli A () A systems biology approach for understanding maternal communication with embryo. Research Training School GEMINI COST Action FA0702, Systems Biology in Maternal Interactions with Ga. Opatija, Croatia, 9 May 2010 - 13 May 2010. RIS download Bibtex download
  • Alminana C, Heath P, Maleki-Dizaji S, Burkitt M, Gil MA, Parrilla I, Cuello C, Sanchez-Osorio J, Vazquez JL, Vazques JM , Roca J et al () A maternal-embryo dialogue exits at very early stages of pregnancy. 4th General Meeting of Maternal Interaction with Gametes and Embryos, GEMINI Cost Action FA0702. Gijon, Spain, 29 September 2011 - 2 October 2011. RIS download Bibtex download
  • Fazeli A () Proceedings of the GEMINI Research Training School, 9-13 May 2010. Opatija, Croatia RIS download Bibtex download
  • Fazeli A () Proceedings of the 3rd General Meeting of GEMINI, 1-3 October 2010. Soustons, France RIS download Bibtex download
  • Fazeli A () Proceedings of the 2nd General Meeting of GEMINI, 1-3 October 2009. Sardini, Italy RIS download Bibtex download
  • Al-Ghareeb S, Caballero-Posadas I, Elliot JA, Sanchez-Lopez J, Maslehat N, Montazeri M & Fazeli A () Understanding innate immunity in maternal-embryo interaction. 4th General Meeting of Maternal Interaction with Gametes and Embryos, GEMINI Cost Action FA0702. Gijon, Spain, 29 September 2011 - 2 October 2011. RIS download Bibtex download
  • Alminana C, Cuelo C, Sanchez-Osorio J, Parrilla I, Gil MA, Lucas X, Vazques JL, Vazquez JM, Roca J, Martinez EA & Fazeli A () Pig embryo at blastocyst stage elicits a local response in sow endometrium. 2nd General Meeting of Maternal Interaction with Gametes and Embryos, GEMINI Cost Action FA0702. Alghero, Italy, 1 October 2009 - 3 October 2009. RIS download Bibtex download
  • Aldarmahi A, Elliott S, Russell J & Fazeli A () Determination of different factors influencing the outcomes of an in vitro model of sperm-oviductal cell interaction. 3rd General Meeting of Maternal Interaction with Gametes and Embryos, GEMINI Cost Action FA0702. Soustons, France, 1 October 2010 - 2 October 2010. RIS download Bibtex download
  • Aldarmahi A, Elliott S, Russell J & Fazeli A () A systemic approach to characterise and define an in vitro model to study the female reproductive tract interaction with spermatozoa. A case study.. Research Training School GEMINI COST Action FA0702, Systems Biology in Maternal Interactions with Ga. Opatija, Croatia, 9 May 2010 - 13 May 2010. RIS download Bibtex download
  • Aldarmahi A, Elliot S & Fazeli A () Establishment of a defined in vitro model for investigation of maternal interactions with gametes and embryo. 5th International Gulf Conference of Saudi Society of Obstetric and Gynaecology. Jeddah, Saudi Arabia, 21 March 2010 - 25 March 2010. RIS download Bibtex download
  • Aldarmahi A, Elliot S, Russell J & Fazeli A () Characterisation of an in vitro system to study the female reproductive tract interaction with spermatozoa. University of Sheffield Medical School Research Meeting. Sheffield, United Kingdom, 5 July 2010 - 6 July 2010. RIS download Bibtex download
  • Aflatoonian R, Tuckerman E, Elliott S, Bruce C, Aflatoonian A, Li TC & Fazeli A () The expression of TLRs during the menstrual cycle and the potential effect of sex hormones on their expression and function. 2nd International Student Award and Congress in Reproductive Medicine. Yazd, Iran, 11 May 2007 - 13 May 2007. RIS download Bibtex download
  • Aldarmahi A, Elliott S & Fazeli A () Establishment of a defined in vitro model for investigation of maternal interactions with gametes and embryo. 31st Annual British Andrology Society Meeting. Belfast, United Kingdom, 19 November 2009 - 20 November 2009. RIS download Bibtex download
  • Aflatoonian R, Tuckerman E, Elliot S, Bruce C, Aflatoonian A, Li TC & Fazeli A () The expression of TLRs during the menstrual cycle. Human Embryonic Stem Cells - Progress Towards Cell Medicine, International Symposium, University of . Sheffield, United Kingdom, 14 July 2006. RIS download Bibtex download
  • Aflatoonian R, Tuckerman E, Elliot S, Bruce C, Aflatoonian A, Li TC & Fazeli A () The expression of TLRs during the menstrual cycle and the potential effect of sex hormones on their expression. Medical School Research Day, University of Sheffield. Sheffield, United Kingdom, 12 June 2006 - 13 June 2006. RIS download Bibtex download
  • Aflatoonian R, Tuckerman E, Elliot S, Bruce C, Aflatoonian A, Li TC & Fazeli A () The expression of TLRs during the menstrual cycle and the potential effect of sex hormones on their expression. 1st International Student Congress on Medical Research. Shiraz, Iran, 23 May 2007 - 25 May 2007. RIS download Bibtex download
  • Aflatoonian R, Monkkonen KS, Elliott S, Bruce C, Georgiou AS & Fazeli A () Regulation of innate immunity in Fallopian tubes by Toll-like receptors and their role in female infertility. Medical School Research Day, University of Sheffield. Sheffield, United Kingdom, 19 June 2007. RIS download Bibtex download
  • Fazeli A, Aflatoonian R, Monkkonen KS, Elliott S, Bruce C & Georgiou AS () Expression of TLRs in Fallopian tube and the effect of sex hormone on their expression. Infection, Inflammation and Immunity Research Day, University of Sheffield. Sheffield, United Kingdom, 11 January 2008. RIS download Bibtex download
  • Aflatoonian R & Fazeli A () Infertility, Innate immunity in the female infertility with emphesize on TLRs. 10th Congress on Reproductive Biomedicine. Tehran, Iran, 23 September 2009 - 25 September 2009. RIS download Bibtex download
  • Aflatoonian R, Monkkonen KS, Elliott S, Bruce C, Georgiou AS & Fazeli A () Expression of TLRs in Fallopian tube and the effect of sex hormone on their expression. Medical School Research Day, University of Sheffield. Sheffield, United Kingdom, 19 June 2007. RIS download Bibtex download
  • Aflatoonian R, Aboussahoud W, Lee KF, Yeung WSB, Tsao SW & Fazeli A () Synergistic effects of sex hormone on the expression and function of TLRs in an immortalized Fallopian tube cell line. Toll2008 - Recent Advances in pattern Recognition. Lisbon, Portugal, 24 September 2008 - 27 September 2008. RIS download Bibtex download
  • Aflatoonian R & Fazeli A () Infertility, innate immunity and female reproductive tract. 3rd International Student Award and Congress in Reproductive Medicine. Yazd, Iran, 17 April 2009 - 19 April 2009. RIS download Bibtex download
  • Aflatoonian B, Fazeli A, Ruban L, Andrews P & Moore H () Differentiation of human ES cells to primordial germ cells in vitro. Fertility 2005, 4th Joint meeting of the British Fertility Society, British Andrology Society and th. Warwick, United Kingdom, 2 April 2005 - 6 April 2005. RIS download Bibtex download
  • Aflatoonian R, Aboussahoud W, Elliott S, Aflatoonian A & Fazeli A () Synergistic effects of sex hormone on the expression and function of TLRs in an immortalized fallopian tube cell line. Medical School Research Day, University of Sheffield. Sheffield, United Kingdom, 9 June 2008 - 10 June 2008. RIS download Bibtex download
  • Aflatoonian R, Aboussahoud W & Fazeli A () Expression of TLRs in Fallopian tube, the combination and separate effect of sex hormones on their expression. Iranian Journal of Reproductive Medicine. Shiraz, Iran, 3 March 2010 - 5 March 2010. RIS download Bibtex download
  • Aflatoonian B, Aflatoonian R, Ruban L, Jones M, Fazeli A & Moore H () Potential of human embryonic stem cells to differentiate to primordial germ cells in vitro. International Congress and Student Award in Reproductive Medicine. Yazd, Iran, 28 December 2005 - 29 December 2005. RIS download Bibtex download
  • Aboussahoud W, Aflatoonian R, Bruce C & Fazeli A () The expression of Toll-like receptor TLR2, TLR3 and TLR4 by human endometrial adenocarcinoma cell lines Ishikawa and Hec-1B. Medical School Research Day, University of Sheffield. Sheffield, United Kingdom, 19 June 2007. RIS download Bibtex download

Reports

  • Colenbrander B, Beekman SPA & Fazeli A (1994) Assisted reproductive technology RIS download Bibtex download
  • Parlevliet J, Bracher V, Pieterse MC, Vos PLAM & Fazeli A (1992) Transvaginal ultrasound-guided follicle aspiration in the mare RIS download Bibtex download
  • Fazeli A & Steenweg W (1991) Sperm-oocyte interaction: sperm-zona pellucida binding RIS download Bibtex download
Research group

Postgraduate Students

  • Shagayegh Basatvat
  • Nurul Jamaludin
  • Nasim Maslehat
  • Mehrnaz Montazeri
  • Tamer Nafee
  • Javier Sanchez-Lopez

Research Support Staff

  • Sarah Elliott
  • Laszlo Tecsi
Teaching interests
  • Train postgraduate research students through MSc and PhD programs in different aspects of maternal communication with gametes and embryo and innate immunity.
  • Contribute to the education of postgraduate students on the MSc in Reproductive and Developmental Medicine course.
  • Coordinate the Reproduction module of Phase 1B in the MBChB Medicine undergraduate course and contribute to the Student Selected Components.
  • Mentor undergraduate and postgraduate students.
Professional activities
  • Trustee of the Infertility Research Trust.
  • Vice-chairman and grant holder of the `Epigenetics and Periconception Environment´ collaborational research project funded by the European Cooperation in Science and Technology (COST Action FA1201) (2012-2016).
  • Member of the Postgraduate Research Committee for the Department of Human Metabolism.
  • Graduate selector for the Academic Unit of Reproductive and Developmental Medicine.
  • Panel member in the Research Grant Review Committee of Royal Society, the Biotechnology and Biological Sciences Research Council (BBSRC) and Irish Research and Technology Council.
  • Member of the Editorial Board for the journal `Reproduction´.
  • Invited presenter on 50 international meetings.
  • Organiser of 17 scientific conferences.
  • Regular external examiner in PhD student thesis and promotion panels.