Dr Jackie Elliott
Department of Oncology and Metabolism
Full contact details
Department of Oncology and Metabolism
The Medical School
Beech Hill Road
I was appointed as a Lecturer in Diabetes at the University of Sheffield in November 2009, and I’m now a Senior Clinical Lecturer. Originally I studied Medicinal Chemistry and was awarded a PhD in 1994. I then became a qualified teacher, before studying Medicine as a mature student at the University of Sheffield (graduated 2002). My role as Senior Clinical Lecturer means that I am able to combine my past experience by dedicating half my time to clinical work, and the remainder to research and teaching.
- Research interests
My research interest in Diabetes started whilst I was a medical student and has continued ever since. My current research interests include complex interventions for patients with diabetes. I’m involved in interventions to examine the best way in which to deliver education to different patient groups, for example those with hypoglycaemia unawareness, or young people, and how best to integrate technology, e.g., the use of insulin pumps, physical activity monitors etc.
• Investigating ways of how best to deliver structured education in diabetes
• Exploring the role of technological advances in the treatment of diabetes
• Examining the effects of low blood glucose on the electrical activity of the heart.
- Assessment of the psychometric properties and refinement of the health and self-management in diabetes questionnaire (HASMID). Health and Quality of Life Outcomes, 18(1). View this article in WRRO
- What are the characteristics of the best type 1 diabetes patient education programmes (from diagnosis to long‐term care), do they improve outcomes and what is required to make them more effective?. Diabetic Medicine, 37(4), 545-554.
- A deep neural network application for improved prediction of HbA1c in type 1 diabetes. IEEE Journal of Biomedical and Health Informatics. View this article in WRRO
- Working with insulin, carbohydrates, ketones and exercise to manage diabetes (WICKED) : evaluation of a self‐management course for young people with Type 1 diabetes. Diabetic Medicine. View this article in WRRO
- PROM validation using paper-based or online surveys : data collection methods affect the sociodemographic and health profile of the sample. Value in Health, 22(8), 845-850. View this article in WRRO
- Painful and Painless Diabetic Neuropathies: What Is the Difference?. Current Diabetes Reports, 19. View this article in WRRO
- Disruptive illness contexts and liminality in the accounts of young people with type 1 diabetes. Sociology of Health & Illness, 41(7), 1289-1304.
- A multicentre, UK, retrospective, observational study to assess the effectiveness of insulin glargine 300 units/ml in treating people with Type 1 diabetes mellitus in routine clinical practice (SPARTA). Diabetic Medicine, 36(1), 110-119.
- Follow-Up Support for Effective type 1 Diabetes self-management (The FUSED Model): A systematic review and meta-ethnography of the barriers, facilitators and recommendations for sustaining self-management skills after attending a structured education programme. BMC Health Services Research, 18. View this article in WRRO
- Estimating a preference-based single index measuring the quality of life impact of self-management for diabetes. Medical Decision Making, 38(6), 699-707. View this article in WRRO
- Experiences of self-management among young adults with type 1 diabetes in the context of a structured education programme: a qualitative study. Diabetic Medicine. View this article in WRRO
- Cost-effectiveness of insulin pumps compared with multiple daily injections both provided with structured education for adults with type 1 diabetes: a health economic analysis of the Relative Effectiveness of Pumps over Structured Education (REPOSE) randomised controlled trial. BMJ Open, 8(4). View this article in WRRO
- Using a Discrete Choice Experiment Involving Cost to Value a Classification System Measuring the Quality-of-Life Impact of Self-Management for Diabetes. Value in Health, 21(1), 69-77. View this article in WRRO
- Developing preference-based measures for diabetes: DHP-3D and DHP-5D. Diabetic Medicine, 34(9), 1264-1275. View this article in WRRO
- Developing a questionnaire to determine the impact of self-management in diabetes: giving people with diabetes a voice. Health and Quality of Life Outcomes, 15. View this article in WRRO
- A cluster randomised trial, cost-effectiveness analysis and psychosocial evaluation of insulin pump therapy compared with multiple injections during flexible intensive insulin therapy for type 1 diabetes: the REPOSE Trial. Health Technology Assessment, 21(20), 1-278. View this article in WRRO
- Relative effectiveness of insulin pump treatment over multiple daily injections and structured education during flexible intensive insulin treatment for type 1 diabetes: cluster randomised trial (REPOSE). BMJ, 356. View this article in WRRO
- Staff experiences of closing out a clinical trial involving withdrawal of treatment: qualitative study. Trials, 18. View this article in WRRO
- Feasibility study of portable technology for weight loss and HbA1c control in type 2 diabetes. BMC Medical Informatics and Decision Making, 16(1), 92-92. View this article in WRRO
- The Impact of Diabetes-Related Complications on Preference-Based Measures of Health-Related Quality of Life in Adults with Type I Diabetes. Medical Decision Making, 36(8), 1020-1033. View this article in WRRO
- Who gains clinical benefit from using insulin pump therapy? A qualitative study of the perceptions and views of health professionals involved in the Relative Effectiveness of Pumps over MDI and Structured Education (REPOSE) trial. Diabetic Medicine, 33(2), 243-251.
- Clinical use and efficacy of biphasic insulin lispro 50/50 in people with insulin treated diabetes – a nationwide evaluation of clinical practice. Current Medical Research and Opinion, 31(3), 493-501. View this article in WRRO
- A cluster randomized controlled non-inferiority trial of 5-day Dose Adjustment for Normal Eating (DAFNE) training delivered over 1 week versus 5-day DAFNE training delivered over 5 weeks: the DAFNE 5 × 1-day trial. Diabetic Medicine, 32(3), 391-398. View this article in WRRO
- Perceptions and experiences of using automated bolus advisors amongst people with type 1 diabetes: A longitudinal qualitative investigation. Diabetes Research and Clinical Practice, 106(3), 443-450. View this article in WRRO
- The Relative Effectiveness of Pumps Over MDI and Structured Education (REPOSE): study protocol for a cluster randomised controlled trial. BMJ Open, 4(9), e006204-e006204. View this article in WRRO
- Substantial reductions in the number of diabetic ketoacidosis and severe hypoglycaemia episodes requiring emergency treatment lead to reduced costs after structured education in adults with Type 1 diabetes.. Diabet Med, 31(7), 847-853. View this article in WRRO
- Assessing the cost-effectiveness of type 1 diabetes interventions: the Sheffield type 1 diabetes policy model.. Diabet Med, 31(4), 477-486.
- Diabetes patients requiring ambulance assistance for severe hypoglycaemia have twice the mortality rate of the general diabetes clinic: identification of possible risk factors. DIABETIC MEDICINE, 31, 26-26.
- A psychoeducational program to restore hypoglycemia awareness: The DAFNE-HART pilot study. Diabetes Care, 37(3), 863-866.
- WICKED: The development and evaluation of a psycho-education programme for young people with type 1 diabetes. Journal of Diabetes Nursing, 18(6), 233-237.
- Experiences, Views, and Support Needs of Family Members of People With Hypoglycemia Unawareness: Interview Study. DIABETES CARE, 37(1), 109-115.
- Type 1 diabetes patients' experiences of, and need for, social support after attending a structured education programme: a qualitative longitudinal investigation. Journal of Clinical Nursing, 23(19-20), 2919-2927.
- Experiences of hypoglycaemia unawareness amongst people with Type 1 diabetes: A qualitative investigation. Chronic Illness, 10(3), 180-191.
- Medical and psychological outcomes for young adults with Type 1 diabetes: no improvement despite recent advances in diabetes care.. Diabet Med, 31(2), 227-231.
- Is consulting patients about their health service preferences a useful exercise?. Qualitative Health Research, 23(7), 876-886.
- Type1 diabetes structured education: what are the core self-management behaviours?. DIABETIC MEDICINE, 30(6), 724-730.
- Using the Medical Research Council framework to develop a complex intervention to improve delivery of care for young people with Type 1 diabetes. DIABETIC MEDICINE, 30, 191-191.
- Using the Medical Research Council framework to develop a complex intervention to improve delivery of care for young people with type 1 diabetes.. Diabet Med, 30(6), e223-e228.
- The cost-effectiveness of Dose Adjustment for Normal Eating (DAFNE) structured education in Type 1 diabetes: an update using the Sheffield Type 1 diabetes policy model. DIABETIC MEDICINE, 30, 133-134.
- The cost-effectiveness of the Dose Adjustment for Normal Eating (DAFNE) structured education programme: an update using the Sheffield Type 1 Diabetes Policy Model. DIABETIC MEDICINE, 30(10), 1236-1244.
- Self-treating hypoglycaemia: a longitudinal qualitative investigation of the experiences and views of people with Type 1 diabetes.. Diabet Med, 30(2), 209-215.
- Eating problems in adolescents with Type 1 diabetes: a systematic review with meta-analysis.. Diabet Med, 30(2), 189-198.
- Eating Disorders in Adolescents with Type 1 Diabetes: A systematic review with meta-analysis. PSYCHOLOGY & HEALTH, 27, 142-142.
- Supporting self-management after attending a structured education programme: a qualitative longitudinal investigation of type 1 diabetes patients’ experiences and views. BMC Public Health, 12. View this article in WRRO
- Experiences of using blood glucose targets when following an intensive insulin regimen: a qualitative longitudinal investigation involving patients with Type 1 diabetes.. Diabet Med, 29(8), 1079-1084.
- Patients' experiences of adjusting insulin doses when implementing flexible intensive insulin therapy: A longitudinal, qualitative investigation. Diabetes Research and Clinical Practice.
- Safety, efficacy and tolerability of exenatide in combination with insulin in the Association of British Clinical Diabetologists nationwide exenatide audit*. Diabetes, Obesity and Metabolism, 13(8), 703-710.
- How and why do patients with Type 1 diabetes sustain their use of flexible intensive insulin therapy? A qualitative longitudinal investigation of patients' self-management practices following attendance at a Dose Adjustment for Normal Eating (DAFNE) course.. Diabet Med, 28(5), 532-538.
- Dose Adjustment for Normal Eating: A qualitative longitudinal exploration of the food and eating practices of type 1 diabetes patients converted to flexible intensive insulin therapy in the UK. Diabetes Research and Clinical Practice, 91(1), 87-93.
- Oral quinine-induced hypoglycaemic seizures. Practical Diabetes International, 27(1), 32-33.
- Large-fiber dysfunction in diabetic peripheral neuropathy is predicted by cardiovascular risk factors.. Diabetes Care, 32(10), 1896-1900. View this article in WRRO
- Risk factors for diabetic peripheral neuropathy in subjects with good glycaemic control: the role of ankle brachial pressure index. DIABETIC MED, 24, 14-14.
- The value of outpatient hysteroscopy in diagnosing endometrial pathology in postmenopausal women with and without hormone replacement therapy.. Acta Obstet Gynecol Scand, 82(12), 1112-1119.
- Agonist-stimulated GTPgamma[35S] binding to 5-HT(1A) receptors in human post-mortem brain.. Eur J Pharmacol, 386(2-3), 313-315.
- Human brain 5-HT1a receptors and antipsychotic action: Effects of quetiapine. SCHIZOPHR RES, 36(1-3), 313-313.
- Tolerance to mu-opioid agonists in human neuroblastoma SH-SY5Y cells as determined by changes in guanosine-5'-O-(3-[35S]-thio)triphosphate binding.. Br J Pharmacol, 121(7), 1422-1428.
- Synthesis and biological evaluation of 14-alkoxymorphinans. 14.1 14-ethoxy-5-methyl substituted indolomorphinans with δ opioid receptor selectivity. Bioorganic & Medicinal Chemistry Letters, 7(2), 151-156.
- Binding of the selectiveδ-ligand [3H]-TIPP in guinea-pig brain and NG 108-15 cells. Regulatory Peptides, 54(1), 221-222.
- [35S]GTPγS binding in SH-SY5Y human neuroblastoma cells as a model for the study of opioid tolerance. Regulatory Peptides, 54(1), 91-92.
- Lack of modulation of μ-opioid agonists by δ-opioid agonists in isolated tissue bioassay preparations. Regulatory Peptides, 53, S41-S42.
- Improving management of type 1 diabetes in the UK: the Dose Adjustment For Normal Eating (DAFNE) programme as a research test-bed. A mixed-method analysis of the barriers to and facilitators of successful diabetes self-management, a health economic analysis, a cluster randomised controlled trial of different models of delivery of an educational intervention and the potential of insulin pumps and additional educator input to improve outcomes. Programme Grants for Applied Research, 2(5), 1-188. View this article in WRRO
- The 5x1 DAFNE Study Protocol: A cluster randomised trial comparing a standard 5 day DAFNE course delivered over 1 week against DAFNE training delivered over 1 day a week for 5 consecutive weeks.. BMC Endocrine Disorders. View this article in WRRO
- Characterisation of mu-opioid receptors on SH-SY5Y cells using naloxonazine and beta-funaltrexamine. European Journal of Pharmacology, 16, 447-450.
- -Opioid receptor subtypes and cross-talk with -receptors.. Trends in Pharmacological Sciences, 14, 84-86.
- Intelligent Data-Driven Model for Diabetes Diurnal Patterns Analysis. IEEE Journal of Biomedical and Health Informatics. View this article in WRRO
- Antinociceptive and toxic effects of (+)epibatidine oxalate attributable to nicotinic agonist activity. British Journal of Pharmacology, 113, 1487-1493.
- Evidence for a lack of modulation of -opioid agonist action by -opioid agonists in the mouse vas deferens and guinea-pig ileum. British Journal of Pharmacology, 114, 1064-1068.
- Does duration of type 1 diabetes affect the outcomes of structured education?. Diabetologia.
Conference proceedings papers
- Modifiable parameters that are associated with improved glycaemic outcomes in patients with Type 1 diabetes using insulin pump therapy. DIABETIC MEDICINE, Vol. 36 (pp 167-167)
- High prevalence of diabetic peripheral neuropathy unmasked by a one-stop microvascular screening service in a hard-to-reach group of young persons with Type 1 diabetes. Diabetic Medicine, Vol. 36 (pp 145-145) View this article in WRRO
- Proceedings of Patient Reported Outcome Measure’s (PROMs) Conference Oxford 2017: Advances in Patient Reported Outcomes Research. Health and Quality of Life Outcomes, Vol. 15(S1) View this article in WRRO
- Staff experiences of closing out a clinical trial involving withdrawal of treatment : qualitative study. Trials, Vol. 18(Suppl 1) (pp 91-91). Liverpool, UK, 7 May 2017 - 10 May 2017. View this article in WRRO
- Proceedings of Patient Reported Outcome Measure’s (PROMs) Conference Sheffield 2016: advances in patient reported outcomes research. Health and Quality of Life Outcomes, Vol. 14(Suppl 1), 9 June 2016 - 9 June 2016. View this article in WRRO
- Is the new Type 1 NICE guidance right? Does basal bolus therapy using analogue insulins from diagnosis in adults with Type 1 diabetes improve outcomes?. DIABETIC MEDICINE, Vol. 33 (pp 188-188)
- The Potential Value of Ongoing Support In Type-1 Diabetes Mellitus With Dafneplus: Exploratory Pre-Trial Cost-Effectiveness Analysis On Proposed Trial End-Point Target For 12-Month Hba1c Improvement. Value in Health, Vol. 17(7) (pp A350-A350)
- DAFNE-HART, a psycho-educational programme to reverse hypoglycaemia unawareness in Type 1 diabetes: report on sustained biomedical benefit at 1 year, and the user experience. DIABETIC MEDICINE, Vol. 31 (pp 8-9)
- Improvements in both glycaemic control and quality of life following structured education in patients with Type 1 diabetes of Black and minority ethnic origin. DIABETIC MEDICINE, Vol. 30 (pp 7-7)
- A psychological intervention for tackling intractable hypoglycaemia in patients with Type 1 diabetes: the pilot study Dose Adjustment for Normal Eating Hypoglycaemia Awareness Restoration Trial (DAFNE-HART). DIABETIC MEDICINE, Vol. 30 (pp 148-148)
- Substantial savings in emergency treatment costs following structured education in patients with Type 1 diabetes. DIABETIC MEDICINE, Vol. 30 (pp 6-7)
- The cost-effectiveness of five week vs one week DAFNE structured education in Type 1 diabetes: a preliminary evaluation using the Sheffield Type 1 diabetes policy model. DIABETIC MEDICINE, Vol. 30 (pp 131-131)
- Podiatry-led neuropathy ulcer clinics allow effective management of limited time and resources. DIABETOLOGIA, Vol. 45 (pp A3-A4)
- Characterization of the μ-Opioid Receptors on SH-SY5Y Cells using β-Funaltrexamine (β-FNA) and Naloxonazine. Biochemical Society Transactions, Vol. 21(4) (pp 469S-469S)
- The Cost-Effectiveness of 5-week versus 1-week DAFNE Structured Education in Type 1 Diabetes: A Preliminary Evaluation Using the Sheffield Type 1 Diabetes Policy Model (Diabetes UK Professional Conference 13-15 March 2013).
- Hypoglycaemia unawareness. Practical Diabetes International, 28(5), 227-232.
- Research group
- Simon Heller
- Solomon Tesfaye
- Julia Lawton
- Teaching interests
My teaching responsibilities include lecturing to Phase 1b of the MBChB course, organising whole year small group teaching for Phase 2 and helping devise revision material for Phase 4. In addition, I am involved in teaching dental students and health care professionals studying for a Masters degree in chronic diseases. As a physician I´m routinely involved in the supervision of junior trainee doctors.
- Professional activities
In striving to improve care for patients with diabetes, I have set up a new multidisciplinary (MDT) hypoglycaemia unawareness clinic, which includes a continuous glucose monitoring facility. I’m clinical lead for the pump service in Sheffield and help run clinics for young people. In addition, I set up co-ordinated departmental diabetes MDT meetings. Recent service audits include: examination of the length of stay and the effect of diabetes, on all inpatients in Sheffield Teaching Hospitals in 2008; the use of antibody testing in confirming the diagnosis of Type 1 or Type 2 diabetes; HbA1c at conception for all diabetes pregnancies in 2010.