Dr Nasreen Akhtar

All publications

Journal articles

• Xanthis I, Souilhol C, Serbanovic-Canic J, Roddie H, Kalli AC, Fragiadaki M, Wong R, Shah DR, Askari JA, Canham L , Akhtar N et al (2019) β1 integrin is a sensor of blood flow direction. Journal of Cell Science. View this article in WRRO
• Akhtar N (2018) Hijacking a Morphogenesis Proteinase for Cancer Cell Invasion. Developmental Cell, 47(2), 135-137. View this article in WRRO
• Akhtar N, Li W, Mironov A & Streuli CH (2016) Rac1 Controls Both the Secretory Function of the Mammary Gland and Its Remodeling for Successive Gestations.. Developmental Cell, 38(5), 522-535. View this article in WRRO
• Akhtar N & Streuli CH (2013) An integrin-ILK-microtubule dependent network orients polarity and lumen formation in glandular epithelium. Nature Cell Biology.
• Jeanes AI, Wang P, Moreno-Layseca P, Paul N, Cheung J, Tsang R, Akhtar N, Foster FM, Brennan K & Streuli CH (2013) Specific β-containing integrins exert differential control on proliferation and two-dimensional collective cell migration in mammary epithelial cells.
• Akhtar N, Hudson KR & Hotchin NA (2009) Co-localization of Rac1 and E-Cadherin in human epidermal keratinocytes. Cell Communication and Adhesion.
• Streuli CH & Akhtar N (2009) Signal co-operation between integrins and other receptor systems. Biochemical Journal, 418, 491.
• Akhtar N, Marlow R, Lambert E, Schatzmann F, Lowe ET, Cheung J, Katz E, Li W, Wu C, Dedhar S , Naylor MJ et al (2009) Molecular dissection of integrin signalling proteins in the control of mammary epithelial development and differentiation. Development, 136(6), 1019-1027.
• Akhtar N & Streuli CH (2006) Rac1 links integrin-mediated adhesion to the control of lactational differentiation in mammary epithelia. Journal of Cell Biology, 173(5), 781-793.
• Zoubiane GS, Valentijn A, Lowe ET, Akhtar N, Bagley S, Gilmore AP & Streuli CH (2004) A role for the cytoskeleton in prolactin-dependent mammary epithelial cell differentiation. Journal of Cell Science, 117(2), 271-280.
• Akhtar N, Woodfield RH, Hodgkin MN, Morse MA, Fuller KJ, Saqib K, Thompson NT & Wakelam MJ (2001) The p85 subunit of phosphoinositide 3-kinase is associated with beta-catenin in the cadherin-based adhesion complex. Biochemical Journal.
• WOODFIELD RJ, HODGKIN MN, AKHTAR N, MORSE MA, FULLER KJ, SAQIB K, THOMPSON NT & WAKELAM MJO (2001) The p85 subunit of phosphoinositide 3-kinase is associated with β-catenin in the cadherin-based adhesion complex. Biochemical Journal, 360(2), 335-344.
• Akhtar N & Hotchin NA (2001) RAC1 Regulates Adherens Junctions through Endocytosis of E-Cadherin. Molecular Biology of the Cell, 12(4), 847-862.
• Hotchin NA, Cover TL & Akhtar N (2000) Cell Vacuolation Induced by the VacA Cytotoxin of Helicobacter pylori Is Regulated by the Rac1 GTPase. Journal of Biological Chemistry, 275(19), 14009-14012.
• Knight B, Laukaitis C, Akhtar N, Hotchin NA, Edlund M & Horwitz AR (2000) Visualizing muscle cell migration in situ. Current Biology, 10(10), 576-585.
• AKHTAR N, LINSTEAD D & WAKELAM MJO (1996) Epidermal growth factor-regulated signal tranduction in hormone dependent and independent breast cancer. Biochemical Society Transactions, 24(3), 373S-373S.
• Mironov A, Fisher M, Narayanan P, Elsayed R, Karabulutoglu M & Akhtar N () Rac1 controls cell turnover and reversibility of the involution process in postpartum mammary glands. PLOS Biology, 21(1), e3001583-e3001583.
• Xanthis I, Souilhol C, Serbanovic-Canic J, Roddie H, Kalli AC, Fragiadaki M, Wong R, Shah DR, Askari JA, Canham L , Akhtar N et al () β1 integrin is a sensor of blood flow direction.

Preprints

• Mironov A, Fisher M, Elsayed R, Karabulutoglu M & Akhtar N () Rac1 controls cell turnover and mammary gland reversibility in post-partum involution, Cold Spring Harbor Laboratory.