Module Overview

Students will have the opportunity to study eight taught 15 credit core modules, and a 60 credit research project. If studying part-time, students also have the option of a Literature Review (30 credits) and professional skills development (15 credit).

Autumn Core Taught Modules:

Fundamentals of Genomics and Human Genetics

An introduction to the key areas of genomics and human genetics, from the structure of a gene through to how genetic variation effects phenotype, giving you an understanding of disease genetics and how genomic medicine can be utilised to elucidate disease mechanisms and biology.

Omics Techniques & Application to Genomic Medicine

Covering areas of ‘omics’ technologies, their interpretation and application in key areas of healthcare such as cancer, rare inherited diseases and infectious diseases, as well as research. A specific focus will be on the approaches supporting the 100,000 Genomes Project.

Genomics of Common & Rare Inherited Diseases

An introduction to the clinical presentation and manifestations of rare inherited and common diseases, and comprehensive overview of the traditional and current strategies and techniques used to identify genes responsible for both common multifactorial and rare inherited diseases.

Molecular Pathology of Cancer

An overview of the molecular mechanisms in cancer development, growth and metastasis, the differences between cancers,  the molecular & cellular actions of anti-cancer treatments, the genomic factors affecting response & resistance to treatment, & the research approaches to anti-cancer drug design & development.

Spring Core Taught Modules:

Pharmacogenomics & Stratified Healthcare

An exploration of the analytical strategies/techniques used in pharmacogenomics and of potential challenges and limitations in this field to ensure the right treatment is offered to the right person at the right time based on the genetics of the individual.

Application of Genomics in Infectious Disease

An overview of how genomics can be used to provide a more accurate diagnosis, predict which drugs are likely to be more effective and monitor treatment and control of infectious disease in individuals and populations.

Intro to Bioinformatics & Interpretation in Genomics

Critical interpretation of genomic research and an introduction to genomic and genetic data resources to align sequence data to the reference genome, critically assess, annotate and interpret findings from genetic and genomic analyses.

Counselling Skills for Genomics

To provide an understanding of legal, social and ethical issues within medical genomics and an awareness of the current national and international legal framework for the governance of processing and sharing genetic information for research purposes.

Advanced Bioinformatics and Health Data Analytics

This module follows from the Intro to Bioinformatics module and aims at providing the theoretical and practical knowledge that health professionals need in order to quantitatively analyse health data and develop personalized treatments for patients. 


Summer Optional Modules

Research Project (60 credits)

Students will complete their masters with a research project, either within the NHS or within the Faculties of Medicine, Dentistry & Health or Science at the University of Sheffield.  Students will be able to tailor their project to their clinical and research interests

Literature Review (30 credits)

This module is to allow students to carry out an in depth literature based project on specific subjects relevant to their area of interest, within genomic medicine, which is suitable for publication.

Professional and Research Skills

Focus on the practicalities involved in performing audits and research with human data, both within and outside of the NHS, in terms of the ethics and research governance procedures that are required prior to collecting samples and data, thereby complementing the ethical and legal knowledge covered in the counselling module.

Advanced Bioinformatics and Health Data Analytics

This is the same module as in Spring term, but repeated to provide flexibility for students.