NEST

Publications in non-epileptic seizures

This is a selection of the recent relevant publications of the group.


General review articles and book chapters

A Carson, RJ Brown, A David, R Duncan, M Edwards, LH Goldstein, R Grunewald, S Howlett, R Kanaan, J Mellers, T Nicholson, M Reuber, A Schrag, J Stone, V Voone on behalf of UK-FNS (2012) Functional neurological symptoms – research since the millennium. JNNP; 83:842-850.

M Reuber, R Mayor (2012) Recent progress in the understanding and treatment of nonepileptic seizures. Current Opinion in  Psychiatry; 25:244-250.

RJ Brown, TU Syed, S Benbadis, WC LaFrance Jr, M Reuber, M. (2011). Psychogenic non-epileptic seizures. Epilepsy & Behavior; 22:85-93.

G Lawton, R Martin, M Reuber (2010) Health related quality of life: Utility and limitations in patients with non-epileptic seizures. In S Schachter and Curt LaFrance (Eds.): Gates and Rowan´s non-epileptic seizures. Cambridge University Press, 149-156.

M Reuber (2010) Psychogenic non-epileptic seizures – quo vadis. Royal College of Psychiatrists Section of Neuropsychiatry News; 1:16-18.

M Reuber (2009) The Etiology of Non-epileptic Seizures: Toward a Biopsychosocial Model. Neurology Clinics; 27:909-924.

M Reuber (2008) Psychogenic Non-epileptic seizures: answers and questions. Epilepsy & Behavior; 12:622-635.

M Reuber, CE Elger (2007) Psychogenic Non-epileptic seizures – an overview. In: Steven Schachter (Ed.) Behavioral Aspects of Epileptology. Demos, 411-419.

M Reuber (2005) Psychogenic nonepileptic seizures: Diagnosis, aetiology, treatment and prognosis. Swiss Archive for Neurology and Psychiatry; 156:47-57.

M Reuber (2003) Psychogenic nonepileptic seizures – a comprehensive review. Advances in Neurosciences; 13:175-204.

M Reuber, CE Elger (2003) Psychogenic nonepileptic seizures – review and update. Epilepsy & Behavior; 4:205-216.

RJ Brown (2002) Epilepsy, dissociation and nonepileptic seizures. In MR Trimble & B Schmitz (Eds.) The Neuropsychiatry of Epilepsy. Cambridge University Press, UK, 189-209.


Presentation and differential diagnosis

K Malmgren, M Reuber, R Appleton. Differential diagnosis of epilepsy. In: S Shorvon, M Cook, R Guerrini, S Lhatoo (Eds.): Epilepsy (Oxford Textbook of Clinical Neurology Series). Oxford University Press; in press

K Whitehead, M Reuber (2012) llness perceptions of neurologists and psychiatrists in relation to epilepsy and nonepileptic attack disorder. Seizure; 21:104-109.

C Monzoni, R Duncan, R Grunewald, M Reuber (2011) Why is it so hard to tell patients they have a medically unexplained problem: a conversation analytic study in neurology outpatients. Patient Education and Counselling; 85:189-200.

C Monzoni, R Duncan, R Grunewald, M Reuber (2011) How do neurologists talk about medically unexplained symptoms: a conversation analytic study. Journal of Psychosomatic Research; 71:377-383.

L Plug, B Sharrack, M Reuber (2011) Metaphors in the description of seizure experiences: common conceptualisations and differential diagnosis. Language and Cognition; 3:209–233.

C Worsley, K Whitehead, R Kandler, M Reuber (2011) Illness perceptions of healthcare workers in relation to epileptic and psychogenic nonepileptic seizures. Epilepsy & Behavior; 20:668-673.

L Plug, B Sharrack, M Reuber (2011) Metaphors in the description of seizure experiences: common conceptualisations and differential diagnosis. Language and Cognition; 3:209-234.

J Barry, M Reuber (2010) The use of hypnosis and linguistic analysis to discriminate between patients with psychogenic non-epileptic seizures and patients with epilepsy. In S Schachter and C LaFrance (Eds.): Gates and Rowan´s non-epileptic seizures. Cambridge University Press, 82-90.

L Plug, B Sharrack, M Reuber (2010) Seizure, fit or attack? The use of diagnostic labels by patients with epileptic and non-epileptic seizures. Applied Linguistics; 31:94-114.

L Plug, B Sharrack, M Reuber (2009) Seizure metaphors differ in patients´ accounts of epileptic and non-epileptic seizures. Epilepsia; 50:994-1000.

M Reuber, C Monzoni, B Sharrack, L Plug (2009) Using Conversation Analysis to distinguish between epileptic and psychogenic non-epileptic seizures: a prospective blinded multi-rater study. Epilepsy & Behavior; 16:139-144.

L Plug, B Sharrack, M Reuber (2009) Seizure metaphors differ in patients´ accounts of epileptic and non-epileptic seizures. Epilepsia; 50:994-1000.

R Thompson, C Isaac, G Rowse, C Tooth, M Reuber (2009) What is it like to receive a diagnosis of nonepileptic seizures? Epilepsy & Behavior; 48:505-515

L Plug, M Reuber (2009) Making the diagnosis in patients with blackouts: it's all in the history. Practical Neurology; 9:4-15

M Schwabe, M Reuber, M Schöndienst , E Gülich (2008) Listening to people with seizures: How can Conversation Analysis help in the differential diagnosis of seizure disorders. Communication & Medicine; 5:59-72.

L Plug, B Sharrack, M Reuber (2008) Conversation analysis can help to distinguish between epilepsy and non-epileptic seizure disorders: A case comparison. Seizure; 18:43-50

M Schwabe, S Howell, M Reuber (2007) Differential diagnosis of seizure disorders: a conversation analytic approach. Social Science and Medicine; 65: 712-724.

M Reuber, L Plug (2007) Listening better to people with seizures – Conversation Analysis can help in the differential diagnosis of seizure disorders. Epilepsy Professional; 5:10-14.

M Reuber, G Fernández, J Bauer, C Helmstaedter, CE Elger (2002) Diagnostic delay in patients with psychogenic non-epileptic seizures. Neurology; 58:493-495.

M Reuber, S Enright, PJ Goulding (2000), Postoperative Pseudostatus: Not everything that shakes is epilepsy. Anaesthesia; 55:74-79.


Aetiology and Epidemiology

A Ponnusamy, J B Marquez, M Reuber (2012) Comparison of heart rate variability parameters during complex partial seizures and psychogenic nonepileptic seizures. Epilepsia; 53:1314-1321.

M Reuber, J Jamnadas-Khoda, M Broadhurst, R Grunewald, S Howell, M Koepp, S Sisodiya, M Walker (2011) Psychogenic nonepileptic seizure manifestations reported by patients and witnesses. Epilepsia; 11:2028-2035.

A Ponnusamy, J B Marquez, M Reuber (2011) Are heart rate variability measures a meaningful biomarker in patients with psychogenic nonepileptic seizures? – a pilot study. Epilepsy & Behavior; 22:685-691.

M Reuber, M Kurthen (2011) Consciousness in Non-Epileptic Attack Disorder. Behavioural Neurology; 24:95-106

G Lawton, R Mayor, M Reuber (2009) Psychogenic non-epileptic seizures and health-related quality of life: The relationship with psychological distress and other physical symptoms. Epilepsy & Behavior; 14:167-171.

M Reuber (2008) Are psychogenic nonepileptic seizures an expression of "neurologic" pathology? In: A Kanner, S Schachter (Eds.): Controversies in Psychiatric Aspects of Epilepsy. Elsevier: 153-178.

N Holman, A Kirkby, S Duncan, RJ Brown (2008) Adult attachment style and childhood interpersonal trauma in non-epileptic attack disorder. Epilepsy Research; 79:84-89.

G Lawton, GA Baker and RJ Brown (2008) Comparison of two types of dissociation in people with epileptic and non-epileptic seizures. Epilepsy & Behavior; 13:333-336.

M Reuber, S Howlett, A Khan, RA Grünewald (2007) Nonepileptic seizures and other functional neurological symptoms: predisposing, precipitating and perpetuating factors. Psychosomatics; 48:230-238

M Reuber, G Baker, DF Smith, DW Chadwick (2004) Failure to recognise psychogenic nonepileptic seizures can cause death. Neurology; 62:834-835.

M Reuber, R Pukrop, J Bauer, R Derfuss, CE Elger (2004) Multidimensional assessment of personality pathology in patients with psychogenic nonepileptic seizures. Journal of Neurology, Neurosurgery and Psychiatry; 75:743-748.

M Reuber, R Pukrop, A Mitchell, J Bauer, CE Elger (2003) Clinical relevance of recurrent psychogenic nonepileptic seizure status. Journal of Neurology; 250:1355-1362.

M Reuber, A O House, R Pukrop, J Bauer, CE Elger (2003) Somatization, dissociation and psychopathology in patients with psychogenic nonepileptic seizures. Epilepsy Research; 57:159-167.

AO House (2003) Epidemiology of somatization and somatoform disorders. Psychiatry; 2:13-15.

M Reuber, C Helmstaedter, J Bauer, G Fernández, A Qurishi, G Widman, CE Elger (2003) Are there physical risk factors for psychogenic nonepileptic seizures in patients with epilepsy? Seizure; 12:561-567.

M Reuber, G Fernández, J Bauer, DD Singh, CE Elger (2002) Interictal EEG abnormalities in patients with psychogenic nonepileptic seizures. Epilepsia; 43:1013-1020.

M Reuber, G Fernández, J Bauer, DD Singh, CE Elger (2002) Interictal EEG abnormalities in patients with psychogenic nonepileptic seizures. Epilepsia; 43:1013-1020.

M Reuber, M Kurthen, T Kral, CE Elger (2002) New-onset psychogenic seizures after intracranial neurosurgery. Acta Neurochirurgica; 144:901-908.

RJ Brown (2002) Epilepsy, dissociation and nonepileptic seizures. In: M Trimble (Ed) & B Schmitz(Ed): The neuropsychiatry of epilepsy: NY, US. Cambridge University Press, 189-209

M Reuber, M Kurthen, T Kral, CE Elger (2002) New-onset psychogenic seizures after intracranial neurosurgery. Acta Neurochirurgica; 144:901-908.

M Reuber, G Fernández, C Helmstaedter, A Qurishi, CE Elger (2002) Evidence of brain abnormality in patients with psychogenic nonepileptic seizures. Epilepsy & Behavior; 3:246-248.

ES Krishnamoorthy, RJ Brown, MR Trimble (2001) Personality and psychopathology in non-epileptic attack disorder (NEAD): A prospective study. Epilepsy & Behavior; 2:418-422.

RJ Brown and MR Trimble (2000) Dissociative psychopathology, non-epileptic seizures, and neurology. Journal of Neurology, Neurosurgery and Psychiatry; 69:285-289.


Treatment

R Mayor, RJ Brown, H Cock, A House, S Howlett, S Singhal, P Smith, M Reuber (2012) Short-term outcome of psychogenic nonepileptic seizures following communication of the diagnosis. Epilepsy & Behavior; in press.

S Baxter, R Mayor, W Baird, R Brown, H Cock, S Howlett, A House, J Messina, P Smith, M Reuber (2012)Understanding patient perceptions following a psycho-educational intervention for psychogenic nonepileptic seizures. Epilepsy & Behavior; 23:487-493.

R Mayor, P Smith, M Reuber (2011) Management of patients with Nonepileptic Attack Disorder in the United Kingdom: a survey of healthcare professionals. Epilepsy & Behavior; 21:402-406.

L Hall-Patch, R Brown, A House, S Howlett, S Kemp, G Lawton, R Mayor, P Smith, M Reuber. (2010) Acceptability and effectiveness of a strategy for the communication of the diagnois of psychogenic non-epileptic seizures. Epilepsia; 51:71-78.

S Howlett, M Reuber (2009) An augmented model of psychodynamic interpersonal therapy for patients with nonepileptic seizures. Psychotherapy Theory, Research, Practise, Training; 46:125-138.

M Reuber, C Burness, S Howlett, J Brazier and R Grunewald (2007) Tailored psychotherapy for patients with functional neurological symptoms: A pilot study. Journal of Psychosomatic Research; 63:625-632.

S Howlett, R Grünewald, A Khan and M Reuber (2007) Engagement in psychological treatment for functional neurologcal symptoms – barriers and solutions. Psychotherapy Theory, Research, Practice, Training; 44:354-360.

M Reuber, S Howlett and S Kemp (2005) Psychological treatment of patients with psychogenic nonepileptic seizures. Expert Review in Neurotherapeutics; 5:737-752.

RA Ruddy and AO House (2005) Psychosocial interventions for conversion disorder. Cochrane Database of Systematic Reviews, CD005331.

M Reuber, M Kurthen, G Fernández, J Schramm and CE Elger (2002) Epilepsy surgery in patients with additional psychogenic seizures. Archives of Neurology; 59:82-86.

M Reuber and AO House (2002) Treating patients with psychogenic non-epileptic seizures. Current Opinion in Neurology; 15:207-211.


Outcome

R Mayor, RJ Brown, H Cock, A House, S Howlett, S Singhal, P Smith, M Reuber. Short-term outcome of psychogenic nonepileptic seizures after communication of the diagnosis. Epilepsy & Behavior; submitted.

R Mayor, S Howlett, R Grunewald, M Reuber (2010) Long-term outcome of brief augmented psychodynamic interpersonal therapy for psychogenic nonepileptic seizures: Seizure control and health care utilization. Epilepsia; 51:1169-1176.

M Reuber, A Mitchell and CE Elger (2005) Measuring outcome in patients with psychogenic nonepileptic seizures: the relevance of seizure remission. Epilepsia; 46:1788-1795.

M Reuber, R Pukrop, J Bauer, C Helmstaedter, N Tessendorf and CE Elger. (2003) Psychogenic nonepileptic seizures: 1 to 10 year follow-up in 164 patients. Annals of Neurology; 53:305-311.


Other Relevant Publications


Other functional disorders and medically unexplained symptoms

RJ Brown, D Skehan, A Chapman, EP Perry, KJ McKenzie, DM Lloyd, C Babbs, P Paine, E Poliakoff (2012) Physical symptom reporting is associated with a tendency to experience somatosensory distortion. Psychosomatic Medicine; 74:648-655.

E Miles, E Poliakoff, RJ Brown (2011). Medically unexplained symptom reports are associated with a decreased response to the rubber hand illusion. Journal of Psychosomatic Research; 71:240-244.

NM Ibrahim, D Martino, BPC van de Warrenburg, NP Quinn, KP Bhatia, RJ Brown, M Trimble, A Schrag (2009). The prognosis of fixed dystonia: A follow-up study. Parkinsonism & Related Disorders; 15:592-597.

DM Lloyd, L Mason, RJ Brown, E Poliakoff (2008) Development of a paradigm for measuring somatic disturbance in clinical populations with medically unexplained symptoms. Journal of Psychosomatic Research; 64:21-24.

RJ Brown (2007). Introduction to the special issue on medically unexplained symptoms: Background information and future directions. Clinical Psychology Review; 27:769-780.

S Howlett, RA Grünewald, A Khan, M Reuber (2007) Engagement in psychological treatment for functional neurological symptoms. Psychotherapy Theory, Research, Practice, Training; 44:354-60.

Brown, R. J. (2006). Medically unexplained symptoms: A new model. Psychiatry; 5:43-47.

RJ Brown (2006). Medically unexplained symptoms. In N Tarrier (Eds.): Case Formulation in Cognitive Behaviour Therapy: The treatment of challenging and complex cases. Brunner-Routledge, 263-292.

M Reuber, AJ Mitchell, SJ Howlett, HL Crimlisk, RA Grünewald (2005) Functional symptoms in neurology: questions and answers. Journal of Neurology, Neurosurgery and Psychiatry; 76:307-314.

RJ Brown (2004). Psychological mechanisms of medically unexplained symptoms: An integrative conceptual model. Psychological Bulletin; 130:793-812.

S Howlett (2004) Writing the link between body and mind – the use of writing with clients suffering from chronic stress-related medical disorders. In G Bolton, S Howlett, C Lago, JK Wright  (Eds.) Writing Cures: an introductory handbook of writing in counselling and therapy. Brunner-Routledge.

S Hatcher, A House (2003) Life events, difficulties and dilemmas in the onset of chronic fatigue syndrome: a case control study Psychological Medicine; 33:1185-1192

M Reuber, Zeidler M, Chataway J, Sadler M (2000) Epileptic Munchausen syndrome by phone. The Lancet; 356:1358.


Dissociation, conversion disorder and somatisation

RJ Brown (In press). Dissociation and somatoform disorders. In F. Kennedy, H. Kennerley & D. Pearson (Eds.), Dissociation and Cognitive Therapy. London: Routledge.

D Spiegel, RJ Loewenstein, R Lewis-Fernández, V Sar, D Simeon, E Vermetten, E Cardeña, RJ Brown, PF Dell (2011). Dissociative disorders in DSM-5. Depression and Anxiety; 28:824-852.

J Stone, WC LaFrance, RJ Brown, D Spiegel, JL Levenson, M Sharpe (2011). Conversion Disorder: current problems and potential solutions for DSM-5. Journal of Psychosomatic Research; 71:369-376.

RJ Brown, R Lewis-Fernández (2011). Culture and conversion disorder: Implications for DSM-5. Psychiatry; 74:187-207.

RJ Brown, AN Danquah, E Miles, E Holmes, E Poliakoff (2010). Attention to the body in non-clinical somatoform dissociation depends on emotional state. Journal of Psychosomatic Research; 69:249-257.

RJ Brown, N Brunt, E Poliakoff, DM Lloyd (2010). Illusory touch and tactile perception in somatoform dissociators. Journal of Psychosomatic Research; 69:241-248.

RJ Brown, A Schrag, ES Krishnamoorthy, MR Trimble (2008) Are patients with somatization disorder highly suggestible? Acta Psychiatrica Scandinavica; 117:232-235.

RJ Brown, MR Trimble, (2007) Dissociative disorders. In J Engel Jr. & TA Pedley: Epilepsy: A Comprehensive Textbook. Lippincott–Raven, Philadelphia, 2819-2827.

RJ Brown, E Cardeña, E Nijenhuis, V Sar, O van der Hart (2007) Should conversion disorder be re-classified as a dissociative disorder in DSM-V? Psychosomatics; 48:369-378.

RJ Brown (2006) Different types of "dissociation" have different psychological mechanisms. Journal of Trauma and Dissociation; 7:7-28.

RJ Brown, A Schrag, MR Trimble (2005) Dissociation, childhood interpersonal trauma, and family functioning in patients with somatization disorder. American Journal of Psychiatry; 162:899-905.

RJ Brown (2005). Dissociation and conversion in psychogenic illness. In M Hallett et al (Eds.): Psychogenic Movement Disorders: Psychobiology and Treatment of a Functional Disorder. Lippincott, Williams & Wilkins, 131-143.

RJ Brown, A Schrag, MR Trimble (2005) Dissociation, childhood interpersonal trauma and family functioning in somatization disorder. American Journal of Psychiatry; 162:899-905.

Schrag, A., Brown, R. J. & Trimble, M. R. (2004). The reliability of self-reported diagnoses in patients with somatoform disorder. Journal of Neurology, Neurosurgery and Psychiatry, 75, 608-611.

A House (2003) Epidemiology of somatization and somatoform disorders. Psychiatry; 2:13-16

RJ Brown, MA Ron (2002) Conversion and Somatoform Disorders. In SV Ramachandran: Encyclopedia of the Human Brain. San Diego, Academic Press 37-49.

C Bass, R Peveler, A House (2001) Somatoform disorders: severe psychiatric illnesses neglected by psychiatrists. British Journal of Psychiatry; 179:11-14.

RJ Brown (2002) The cognitive psychology of dissociative states. Cognitive Neuropsychiatry; 7:221-235.


Psychotherapy

G Paley, J Cahill, M Barkham, DA Shapiro, J Jones, S Patrick, E Reid (2008) The effectiveness of psychodynamic-interpersonal psychotherapy in routine clinical practice: A benchmarking comparison. Psychology and Psychotherapy: Theory, Research and Practice; 85:157-175.

M Barkham, WB Stiles, J Connell, E Twigg, C Leach, M Lucock, et al. (2008) Effects of psychological therapies in randomized trials and practice-based studies. British Journal Clinical Psychology; 47:397-415.

WB Stiles, M Barkham, J Mellor-Clark, J Connell (2008) Effectivesss of cognitive-behavioural, person-centered, and psychodynamic therapies in UK primary care routine practice: Replication with a larger sample. Psychological Medicine; 38:677-688.

A Rudkin, S Llewelyn, G Hardy, WB Stiles, M Barkham (2007) Therapist and client processes affecting assimilation and outcome in brief psychotherapy. Psychotherapy Research; 17:613-621.

N Stulz, W Lutz, C Leach, M Lucock, M Barkham (2007) Shapes of early change in psychotherapy under routine outpatient conditions. Journal of Consulting and Clinical Psychology; 75:864-874.

G Bolton, S Howlett, C Lago, JK Wright (eds)(2004) Writing Cures: Introductory Handbook of Writing in Counselling and Psychotherapy. Hove and New York, Brunner-Routledge.

S Howlett, E Guthrie (2001) The Use of Farewell Letters in the Context of Brief Psychodynamic Interpersonal Therapy with IBS Patients. British Journal of Psychotherapy; 18:52-67.

M Barkham, A Rees, DA Shapiro, WB Stiles, RM Agnew, J Halstead, A Culverwell, VMG Harrington (1996) Outcomes of time-limited psychotherapy in applied settings: Replicating the Second Sheffield Psychotherapy Project. Journal of Consulting and Clinical Psychology; 64:1079-1085.

GE Hardy, M Barkham, DA Shapiro, S Reynolds, A Rees, WB Stiles (1995) Client beliefs, expectancy and outcome in cognitive-behavioural and psychodynamic-interpersonal therapy. British Journal of Clinical Psychology; 34:555-569.

DA Shapiro, A Rees, M Barkham, GE Hardy, S Reynolds, M Startup (1995) Effects of treatment duration and severity of depression on the maintenance of gains following cognitive-behavioral and psychodynamic-interpersonal psychotherapy. Journal of Consulting and Clinical Psychology; 63:378-387.

DA Shapiro, M Barkham, A Rees, GE Hardy, S Reynolds, M Startup (1994) Effects of treatment duration and severity of depression on the effectiveness of cognitive-behavioral and psychodynamic-interpersonal psychotherapy. Journal of Consulting and Clinical Psychology; 62:522-534.

M Barkham (1989) Exploratory therapy in two-plus-one sessions: I - Rationale for a brief psychotherapy model. British Journal of Psychotherapy; 6:81-88.

M Barkham, RF Hobson (1989) Exploratory therapy in two-plus-one sessions: II - A single case study. British Journal of Psychotherapy; 6:89-100.