Dr Saba Balasubramanian [MS, FRCSEd (Gen Surg), DMI, PhD]

Dr Saba Balasubramanian

Department of Oncology & Metabolism
The Medical School
Beech Hill Road
S10 2RX

Office: EU35

+44 (0) 114 226 1379
Email: s.p.balasubramanian@sheffield.ac.uk


I joined the University of Sheffield in 2001 as a lecturer in Surgical Oncology and was involved in the ‘Sheffield Breast Cancer Study’ evaluating low penetrance genes predisposing to susceptibility and severity of breast cancer. I completed my PhD and continued as lecturer and specialist registrar in General Surgery untill I completed training in General and Endocrine Surgery in 2009. I then did a fellowship in Endocrine Surgery in King’s College Hospital, London. I returned to work in Sheffield as a NIHR funded Academic Clinical Senior Lecturer from January 2010 to 2015.
I now work as a Consultant Endocrine Surgeon and Honorary Senior Lecturer in Sheffield.

Research Interests

• Thyroid cancer – epidemiology, diagnosis and over-diagnosis and management
• Improvements in the management of primary hyperparathyroidism
• Novel technology to aid parathyroid identification and preservation in thyroid and parathyroid surgery
• Application of ‘evidence based medicine’ to surgical practice.

Teaching Interests

My teaching interests include teaching ‘Research Methodology and Critical Appraisal’ for surgical trainees in addition to undergraduate and postgraduate teaching in General and Endocrine Surgery.

I run a module on ‘Cancer epidemiology’ as part of the department’s MSc in Translational Oncology master’s program.

Professional activities

  • PI in several clinical and translational studies
  • Module lead in MSc in Translational Oncology
  • Chair of the regional Thyroid Cancer network specific subgroup
  • Consultant Endocrine Surgeon, STH

Current Projects

• PI in several clinical and translational studies
• Module lead in MSc in Translational Oncology
• Lead clinician for thyroid cancer in Sheffield Teaching Hospitals
• Clinical lead for endocrine and general surgery and consultant endocrine surgeon, STH

Key Publications in 2014

• Parker WA, Edafe O, Balasubramanian SP. Long-term treatment-related morbidity in differentiated thyroid cancer: a systematic review of the literature. Pragmat Obs Res. 2017 May 16; 8: 57-67. PMID:28553154
• Kheder S, Sisley K, Hadad S, Balasubramanian SP. Effects of prolonged exposure to low dose metformin in thyroid cancer cell lines. J Cancer. 2017 Apr 9;8(6):1053-1061. PMID: 28529619
• Hussain YS, Hookham JC, Allahabadia A, Balasubramanian SP. Epidemiology, management and outcomes of Graves' disease-real life data. Endocrine. 2017 Jun;56(3):568-578. PMID: 28478488
• Mathiesen JS, Habra MA, Bassett JH, Choudhury SM, Balasubramanian SP, Howlett TA, Robinson BG, Gimenez-Roqueplo AP, Castinetti F, Vestergaard P, Frank-Raue K. Risk profile of the RET A883F germline mutation: an international collaborative study. J Clin Endocrinol Metab. 2017 Mar 17. PMID: 28323957
• Akram R, Wiltshire JJ, Wadsley J, Balasubramanian SP. Adult thyroglossal duct carcinoma of thyroid epithelial origin: a retrospective observational study. Indian J Otolaryngol Head Neck Surg. 2016 Dec;68(4):522-527. PMID: 27833882
• Wiltshire JJ, Drake TM, Uttley L, Balasubramanian SP. Systematic Review of Trends in the Incidence Rates of Thyroid Cancer. Thyroid. 2016 Nov;26(11):1541-1552. PMID: 27571228
• Hookham J, Truran P, Allahabadia A, Balasubramanian SP. Patients' perceptions and views of surgery and radioiodine ablation in the definitive management of Graves' disease. Postgrad Med J. 2016 Sep 20. pii: postgradmedj-2015-133756. doi: 10.1136/postgradmedj-2015-133756. [Epub ahead of print]. PMID: 27651496
• Hookham J, Collins EE, Allahabadia A, Balasubramanian SP. Variation in the use of definitive treatment options in the management of Graves' disease: a UK clinician survey. Postgrad Med J. 2016 Aug 16. pii: postgradmedj-2016-134187. doi: 10.1136/postgradmedj-2016-134187. [Epub ahead of print]. PMID: 27531964
• Hillary SL, Hemead H, Berthoud M, Balasubramanian SP. A case report on acute severe hyponatraemia following parathyroid surgery for primary hyperparathyroidism-A rare but life threatening complication. Int J Surg Case Rep. 2016;21:136-8. doi: 10.1016/j.ijscr.2016.03.001. Epub 2016 Mar 9. PMID: 26994458
• Shariff U, Seretis C, Lee D, Balasubramanian SP. The role of multimedia in surgical skills training and assessment. Surgeon. 2016 Jun;14(3):150-63. doi: 10.1016/j.surge.2015.10.003. Epub 2015 Nov 11. Review. PMID: 26577145

Book Chapters

Balasubramanian SP. Section Editor. Endocrine. Surgical Oncology: Theory and Multidisciplinary Practice. Second Edition. Edited by Graeme Poston, Lynda Wyld and Riccardo Audisio. ISBN 928148701990
• Bagul A, Balasubramanian SP. Adrenal Tumours. Chapter 43. Endocrine Section. Surgical Oncology: Theory and Multidisciplinary Practice. Second Edition. Edited by Graeme Poston, Lynda Wyld and Riccardo Audisio. ISBN 928148701990
Balasubramanian SP, Smith D. Disorders of the thyroid gland. In part 2: Specialist General Surgery. A chapter in ‘Essential Surgical Practice: Higher Surgical Training in General Surgery’, Fifth Edition, 2015. Edited by Alfred Cuschieri and George Hanna. ISBN 9781444137606
Balasubramanian SP. (2013). The thyroid, parathyroid and adrenal glands. In M. Schein, P. N. Rogers, A. Leppäniemi, & D. Rosin (Eds.), Schein's Common Sense Prevention and Management of Surgical Complications (pp. 413-430). tfm Publishing Limited.
Balasubramanian SP. (2011). Oxford Textbook of Endocrinology and Diabetes. In J. Wass, & P. Stewart (Eds.), Oxford Textbook of Endocrinology and Diabetes. Oxford University Press, USA.
Balasubramanian SP, & Thomas WEG. (2010). The Neck and the Salivary Glands. In J. Black, N. Browse, K. Burnand, W. Thomas, & S. Corbett (Eds.), Browse's Introduction to the Investigation and Management of Surgical Disease (pp. 277-294). Hodder Arnold.
Balasubramanian SP, & Harrison B. (2007). Adrenal Tumors. In G. J. Poston, R. D. Beauchamp, & T. Ruers (Eds.), Textbook of Surgical Oncology (pp. 327-338). Informa HealthCare.


For a full list, please see link to the right.